ONLINE DATABASE SEARCH - DMID-LS-113-MEMO
1. 58219 DMID-LS-113; SCIFINDER-DMID-2/27/2006 ; DMID-LSLOAD
Tetrahydro-b-carboline derivatives useful for the treatment of human papillomavirus infection
Gudmundsson, Kristjan, Miller, John Franklin, Sherrill, Ronald George, and Turner, Elizabeth Madalena
PATENT: WO 2006015035 ISSUE DATE: 20060209
APPLICATION: 2005 PP: 51 pp.
ASSIGNEE: (Smithkline Beecham Corporation, USA
2. 58220 DMID-LS-113; SCIFINDER-DMID-2/27/2006 ; DMID-LSLOAD
Cidofovir peptide conjugates as prodrugs, their preparation, and therapeutic use thereof
McKenna, Charles E
PATENT: WO 2006014429 ISSUE DATE: 20060209
APPLICATION: 2005 PP: 30 pp.
ASSIGNEE: (University of Southern California (LA), USA
3. 58221 DMID-LS-113; WOS-DMID-2/27/2006 ; DMID-LSLOAD
Microwave-Assisted Synthesis and Anti-Yfv Activity of 2,3-Diaryl-1,3-Thiazolidin-4-Ones
Sriram, D., Yogeeswari, P., and Kumar, T.
Journal of Pharmacy and Pharmaceutical Sciences 2005. 8(3 ): 426-429
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235183400007
4. 58222 DMID-LS-113; PUBMED-DMID-2/27/2006 ; DMID-LSLOAD
In vitro characterization of the anti-hepatitis B virus activity and cross-resistance profile of 2',3'-dideoxy-3'-fluoroguanosine
Jacquard, AC, Brunelle, MN, Pichoud, C, Durantel, D, Carrouee-Durantel, S, Trepo, C, and Zoulim, F
Antimicrob Agents Chemother 2006. 50(3): 955-61
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16495257&dopt=abstract
5. 58223 DMID-LS-113; PUBMED-DMID-2/27/2006 ; DMID-LSLOAD
Preclinical Profile of VX-950, a Potent, Selective, and Orally Bioavailable Inhibitor of Hepatitis C Virus NS3-4A Serine Protease
Perni, RB, Almquist, SJ, Byrn, RA, Chandorkar, G, Chaturvedi, PR, Courtney, LF, Decker, CJ, Dinehart, K, Gates, CA, Harbeson, SL, Heiser, A, Kalkeri, G, Kolaczkowski, E, Lin, K, Luong, YP, Rao, BG, Taylor, WP, Thomson, JA, Tung, RD, Wei, Y, Kwong, AD, and Lin, C
Antimicrob Agents Chemother 2006. 50(3): 899-909
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16495249&dopt=abstract
6. 58224 DMID-LS-113; SCIFINDER-DMID-2/27/2006 ; DMID-LSLOAD
Agents with leukotriene B4-like antiviral (enveloped RNA) activities
Gosselin, Jean and Borgeat, Pierre
PATENT: US 2006025479 ISSUE DATE: 20060202
APPLICATION: 2004-11016 PP: 28 pp., Cont.-in-part of U.S. Ser. No. 683,882, abandoned.
ASSIGNEE: (Can.)
7. 58225 DMID-LS-113; PUBMED-DMID-2/27/2006 ; DMID-LSLOAD
Selective anti-cytomegalovirus compounds discovered by screening for inhibitors of subunit interactions of the viral polymerase
Loregian, A and Coen, DM
Chem Biol 2006. 13(2): 191-200
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16492567&dopt=abstract
8. 58226 DMID-LS-113; SCIFINDER-DMID-2/27/2006 ; DMID-LSLOAD
Pyridinylamines and their preparations, pharmaceutical compositions and use for prophylaxis or treatment of various diseases
Eickhoff, Jan Eike, Hafenbradl, Doris, Schwab, Wilfried, Cotton, Matthew, Klebl, Bert Matthias, Zech, Birgit, Mueller, Stefan, Harris, John, Savic, Vladimir, Macritchie, Jackie, Sherborne, Brad, and Le, Joelle
PATENT: WO 2006010637 ISSUE DATE: 20060202
APPLICATION: 2005 PP: 177 pp.
ASSIGNEE: (Gpc Biotech AG, Germany
9. 58227 DMID-LS-113; PUBMED-DMID-2/27/2006 ; DMID-LSLOAD
Identification of compounds that inhibit the interaction between core and surface protein of hepatitis B virus
Asif-Ullah, M, Choi, KJ, Choi, KI, Jeong, YJ, and Yu, YG
Antiviral Res 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16487605&dopt=abstract
10. 58228 DMID-LS-113; PUBMED-DMID-2/27/2006 ; DMID-LSLOAD
Inhibition of cell proliferation by SARS-CoV infection in Vero E6 cells
Mizutani, T, Fukushi, S, Iizuka, D, Inanami, O, Kuwabara, M, Takashima, H, Yanagawa, H, Saijo, M, Kurane, I, and Morikawa, S
FEMS Immunol Med Microbiol 2006. 46(2): 236-43
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16487305&dopt=abstract
11. 58229 DMID-LS-113; SCIFINDER-DMID-2/27/2006 ; DMID-LSLOAD
Preparation of 5-aza-7-deazadeazapurine and C-branched nucleosides as antiviral agents for treating Flaviviridae
Gosselin, Gilles, La Colla, Paolo, Seela, Frank, Storer, Richard, Dukhan, David, and Leroy, Frederic
PATENT: WO 2006000922 ISSUE DATE: 20060105
APPLICATION: 2005 PP: 115 pp.
ASSIGNEE: (Idenix (Cayman) Limited, Cayman I.
12. 58230 DMID-LS-113; PUBMED-DMID-2/27/2006 ; DMID-LSLOAD
Synthesis and biological evaluation of phosphonated dihydroisoxazole nucleosides
Romeo, G, Iannazzo, D, Piperno, A, Romeo, R, Saglimbeni, M, Chiacchio, MA, Balestrieri, E, Macchi, B, and Mastino, A
Bioorg Med Chem 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16480883&dopt=abstract
13. 58231 DMID-LS-113; PUBMED-DMID-2/27/2006 ; DMID-LSLOAD
Design and synthesis of 2,3,4,9-tetrahydro-1H-carbazole and 1,2,3,4-tetrahydro-cyclopenta[b]indole derivatives as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymerase
Gopalsamy, A, Shi, M, Ciszewski, G, Park, K, Ellingboe, JW, Orlowski, M, Feld, B, and Howe, AY
Bioorg Med Chem Lett 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16480869&dopt=abstract
14. 58232 DMID-LS-113; WOS-DMID-2/27/2006 ; DMID-LSLOAD
P1 and P1 ' Optimization of [3,4]-Bicycloproline P2 Incorporated Tetrapeptidyl Alpha-Ketoamide Based Hcv Protease Inhibitors
Chen, S. et al.
Letters in Drug Design & Discovery 2005. 2(2): 118-123
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235081400006
15. 58233 DMID-LS-113; WOS-DMID-2/27/2006 ; DMID-LSLOAD
Anti-Viral Therapies for Hepatitis C Virus Infection: Current Options and Evolving Candidate Drugs
Fanning, L.
Letters in Drug Design & Discovery 2005. 2(2): 150-161
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235081400012
16. 58234 DMID-LS-113; WOS-DMID-2/27/2006 ; DMID-LSLOAD
Phenyldihydroxypyrimidines as Hcvns5b Rna Dependent Rna Polymerase Inhibitors. Part 1: Amides and Ureas
Crescenzi, B. et al.
Letters in Drug Design & Discovery 2005. 2(6): 451-455
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235167900004
17. 58235 DMID-LS-113; PUBMED-DMID-2/27/2006 ; DMID-LSLOAD
Comparative Activities of Oseltamivir and A-322278 in Immunocompetent and Immunocompromised Murine Models of Influenza Virus Infection
Ison, MG, Mishin, VP, Braciale, TJ, Hayden, FG, and Gubareva, LV
J Infect Dis 2006. 193(6): 765-772
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16479509&dopt=abstract
18. 58236 DMID-LS-113; WOS-DMID-2/27/2006 ; DMID-LSLOAD
Phenyldihydroxypyrimidines as Hcvns5b Rna Dependent Rna Polymerase Inhibitors. Part Ii: Sulfonamides
Ponzi, S. et al.
Letters in Drug Design & Discovery 2005. 2(6): 456-461
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235167900005
19. 58237 DMID-LS-113; PUBMED-DMID-2/27/2006 ; DMID-LSLOAD
Novel Inhibitors of Hepatitis C Virus RNA-dependent RNA Polymerases
Lee, G, Piper, DE, Wang, Z, Anzola, J, Powers, J, Walker, N, and Li, Y
J Mol Biol 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16476448&dopt=abstract
20. 58238 DMID-LS-113; WOS-DMID-2/27/2006 ; DMID-LSLOAD
Inhibitors of Hepatitis C Virus Ns3 Center Dot 4a Protease: P-2 Proline Variants
Farmer, L. et al.
Letters in Drug Design & Discovery 2005. 2(7): 497-502
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235168000001
21. 58239 DMID-LS-113; WOS-DMID-2/27/2006 ; DMID-LSLOAD
Antiviral Activity of Transiently Expressed Ifn-Kappa Is Cell-Associated
Buontempo, P. et al.
Journal of Interferon and Cytokine Research 2006. 26(1): 40-52
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235063500006
22. 58240 DMID-LS-113; PUBMED-DMID-2/27/2006 ; DMID-LSLOAD
Characterization of the antiviral effects of interferon-alpha against a SARS-like coronoavirus infection in vitro
Zorzitto, J, Galligan, CL, Ueng, JJ, and Fish, EN
Cell Res 2006. 16(2): 220-229
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16474437&dopt=abstract
23. 58241 DMID-LS-113; WOS-DMID-2/27/2006 ; DMID-LSLOAD
Development of Antiviral Drugs Targeting the Flaviviruses Fusion Mechanism
Kampmann, T. et al.
Febs Journal 2005. 272: 553
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000234826102702
24. 58242 DMID-LS-113; PUBMED-DMID-2/27/2006 ; DMID-LSLOAD
Hammerhead ribozymes with cleavage site specificity for NUH and NCH display significant anti-hepatitis C viral effect in vitro and in recombinant HepG2 and CCL13 cells
Gonzalez-Carmona, MA, Schussler, S, Serwe, M, Alt, M, Ludwig, J, Sproat, BS, Steigerwald, R, Hoffmann, P, Quasdorff, M, Schildgen, O, and Caselmann, WH
J Hepatol 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16469406&dopt=abstract
25. 58243 DMID-LS-113; WOS-DMID-2/27/2006 ; DMID-LSLOAD
Peroxisome Proliferator-Activated Receptor Alpha Antagonism Inhibits Hepatitis C Virus Replication
Rakic, B. et al.
Chemistry & Biology 2006. 13(1): 23-30
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235090900006
26. 58244 DMID-LS-113; SCIFINDER-DMID-2/27/2006 ; DMID-LSLOAD
ent-epiafzelechin-(4a->8)-epiafzelechin extracted from Cassia javanica inhibits herpes simplex virus type 2 replication
Cheng, Hua-Yew, Yang, Chien-Min, Lin, Ta-Chen, Shieh, Den-En, and Lin, Chun-Ching
Journal of Medical Microbiology 2006. 55(2): 201-206
27. 58245 DMID-LS-113; SCIFINDER-DMID-2/27/2006 ; DMID-LSLOAD
2-Substituted Furans from the Roots of Polyalthia evecta
Kanokmedhakul, Somdej, Kanokmedhakul, Kwanjai, Kantikeaw, Itsara, and Phonkerd, Nutchanat
Journal of Natural Products 2006. 69(1): 68-72
28. 58246 DMID-LS-113; PUBMED-DMID-2/27/2006 ; DMID-LSLOAD
The protein phosphatase 2A represents a novel cellular target for hepatitis C virus NS5A protein
Georgopoulou, U, Tsitoura, P, Kalamvoki, M, and Mavromara, P
Biochimie 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16460864&dopt=abstract
29. 58247 DMID-LS-113; PUBMED-DMID-2/27/2006 ; DMID-LSLOAD
Smallpox
Moore, ZS, Seward, JF, and Lane, JM
Lancet 2006. 367(9508): 425-35
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16458769&dopt=abstract
30. 58248 DMID-LS-113; SCIFINDER-DMID-2/27/2006 ; DMID-LSLOAD
Owl monkey polynucleotide encoding a TRIM5-cyclophilin A fusion protein, and its use in treating HIV-1 and other viral infections
Luban, Jeremy and Sayah, David
PATENT: WO 2006014422 ISSUE DATE: 20060209
APPLICATION: 2005 PP: 62 pp.
ASSIGNEE: (The Trustees of Columbia University In the City of New York, USA
31. 58249 DMID-LS-113; WOS-DMID-2/27/2006 ; DMID-LSLOAD
Inhibition of the Hepatitis B Virus Replication in Vitro by an Oligodeoxynucleotide Containing Cytidine-Guano Sine Motifs
Ning, L. et al.
Immunology Letters 2006. 102(1): 60-66
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000234768400008
32. 58250 DMID-LS-113; SCIFINDER-DMID-2/27/2006 ; DMID-LSLOAD
Synthesis and antiviral activities of 1,2,3-triazole functionalized thymidines: 1,3-dipolar cycloaddition for efficient regioselective diversity generation
Zhou, Longhu, Amer, Adel, Korn, Michael, Burda, Robert, Balzarini, Jan, De Clercq, Erik, Kern, Earl R, and Torrence, Paul F
Antiviral Chemistry & Chemotherapy 2005. 16(6): 375-383
33. 58251 DMID-LS-113; WOS-DMID-2/27/2006 ; DMID-LSLOAD
Aromatic Polycationic Molecules With Restricted Conformations: an Alternative Approach to Antiherpes Agents
Tsotinis, A. et al.
Letters in Drug Design & Discovery 2005. 2(5): 424-427
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235167800009
34. 58252 DMID-LS-113; SCIFINDER-DMID-2/27/2006 ; DMID-LSLOAD
RNA-dependent RNA polymerase from SARS CoV and its homologs from other coronaviruses and their use in molecular biology and drug screening
Imbert, Isabelle, Guillemot, Jean-Claude, Canard, Bruno, and Ferron, Francois-Patrice
PATENT: EP 1619246 ISSUE DATE: 20060125
APPLICATION: 2004-29735 PP: 27 pp.
ASSIGNEE: (Universite de la Mediterranee, Aix-Marseille II Fr.
35. 58253 DMID-LS-113; LR-14709-LWC; SCIFINDER-DMID-2/27/2006 ; DMID-LSLOAD
Pyridine N-oxide derivatives are inhibitory to the human SARS and feline infectious peritonitis coronavirus in cell culture
Balzarini, Jan, Keyaerts, Els, Vijgen, Leen, Vandermeer, Frank, Stevens, Miguel, De Clercq, Erik, Egberink, Herman, and Van Ranst, Marc
Journal of Antimicrobial Chemotherapy 2006. 57(3): 472-481
36. 58254 DMID-LS-113; SCIFINDER-DMID-2/27/2006 ; DMID-LSLOAD
Therapeutic agents for human papilloma virus disease and anti human immunodeficiency virus medicine
Sakagami, Hiroshi, Kawazoe, Yutaka, Otsuki, Mamitarou, Inaba, Youichi, Sai, Bun, Horiuchi, Akira, Nakajima, Hideki, and Aratsu, Chiaki
PATENT: WO 2006001364 ISSUE DATE: 20060105
APPLICATION: 2005 PP: 28 pp.
ASSIGNEE: (Nihonsyouyaku Laboratory Corporation, Japan
37. 58255 DMID-LS-113; WOS-DMID-2/27/2006 ; DMID-LSLOAD
Avian Influenza Virus Infections in Humans
Wong, S. and Yuen, K.
Chest 2006. 129(1): 156-168
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000234944900026