ONLINE DATABASE SEARCH - DMID-LS-103-MEMO
1. 57888 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
Antiviral cyclic D, L-a-peptides: Targeting a general biochemical pathway in virus infections
Horne, WSeth, Wiethoff, Christopher M, Cui, Chunli, Wilcoxen, Keith M, Amorin, Manuel, Ghadiri, MReza, and Nemerow, Glen R
Bioorganic & Medicinal Chemistry 2005. 13(17): 5145-5153
2. 57889 DMID-LS-103; WOS-DMID-10/11/2005 ; DMID-LSLOAD
Development of a Homogeneous Screening Assay for Automated Detection of Antiviral Agents Active Against Severe Acute Respiratory Syndrome-Associated Coronavirus
Ivens, T. et al.
Journal of Virological Methods 2005. 129(1): 56-63
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000231936500007
3. 57890 DMID-LS-103; WOS-DMID-10/11/2005 ; DMID-LSLOAD
Antisense Phosphorothioate Oligonucleotide Inhibition of Hepatitis C Virus Genotype 4 Replication in Hepg2 Cells
El Awady, M.
Journal of Biotechnology 2005. 118: S79
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000231195200268
4. 57891 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Broad-spectrum inhibitor of viruses in the Flaviviridae family
Ojwang, JO, Ali, S, Smee, DF, Morrey, JD, Shimasaki, CD, and Sidwell, RW
Antiviral Res 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16199098&dopt=abstract
5. 57892 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern
Bright, RA, Medina, MJ, Xu, X, Perez-Oronoz, G, Wallis, TR, Davis, XM, Povinelli, L, Cox, NJ, and Klimov, AI
Lancet 2005. 366(9492): 1175-81
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16198766&dopt=abstract
6. 57893 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Avian influenza A (H5N1) infection in humans
Beigel, JH, Farrar, J, Han, AM, Hayden, FG, Hyer, R, de, Jong MD, Lochindarat, S, Nguyen, TK, Nguyen, TH, Tran, TH, Nicoll, A, Touch, S, and Yuen, KY
N Engl J Med 2005. 353(13): 1374-85
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16192482&dopt=abstract
7. 57894 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Neuraminidase inhibitors for influenza
Moscona, A
N Engl J Med 2005. 353(13): 1363-73
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16192481&dopt=abstract
8. 57895 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Synthesis and Structure-Activity Relationship of the First Nonpeptidergic Inverse Agonists for the Human Cytomegalovirus Encoded Chemokine Receptor US28
Hulshof, JW, Casarosa, P, Menge, WM, Kuusisto, LM, van, der Goot H, Smit, MJ, de, Esch IJ, and Leurs, R
J Med Chem 2005. 48(20): 6461-71
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16190772&dopt=abstract
9. 57896 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
Antiviral random sequence oligonucleotides targeting viral families
Vaillant, Andrew and Juteau, Jean-Marc
PATENT: US 2005196382 ISSUE DATE: 20050908
APPLICATION: 2004-52308 PP: 100 pp., Cont.-in-part of U.S. Ser. No. 661,402.
ASSIGNEE: (Replicor, Inc. Can.
10. 57897 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Synthesis and Structure-Activity Relationships of Novel Anti-hepatitis C Agents: N(3),5'-Cyclo-4-(beta-d-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one Derivatives
Wang, P, Du, J, Rachakonda, S, Chun, BK, Tharnish, PM, Stuyver, LJ, Otto, MJ, Schinazi, RF, and Watanabe, KA
J Med Chem 2005. 48(20): 6454-60
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16190771&dopt=abstract
11. 57898 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Simple but Highly Effective Three-Dimensional Chemical-Feature-Based Pharmacophore Model for Diketo Acid Derivatives as Hepatitis C Virus RNA-Dependent RNA Polymerase Inhibitors
Di Santo, R, Fermeglia, M, Ferrone, M, Paneni, MS, Costi, R, Artico, M, Roux, A, Gabriele, M, Tardif, KD, Siddiqui, A, and Pricl, S
J Med Chem 2005. 48(20): 6304-6314
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16190757&dopt=abstract
12. 57899 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Design, Synthesis, and Biological Activity of m-Tyrosine-Based 16- and 17-Membered Macrocyclic Inhibitors of Hepatitis C Virus NS3 Serine Protease
Chen, KX, Njoroge, FG, Pichardo, J, Prongay, A, Butkiewicz, N, Yao, N, Madison, V, and Girijavallabhan, V
J Med Chem 2005. 48(20): 6229-35
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16190750&dopt=abstract
13. 57900 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Clevudine inhibits hepatitis delta virus viremia: a pilot study of chronically infected woodchucks
Casey, J, Cote, PJ, Toshkov, IA, Chu, CK, Gerin, JL, Hornbuckle, WE, Tennant, BC, and Korba, BE
Antimicrob Agents Chemother 2005. 49(10): 4396-9
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16189132&dopt=abstract
14. 57901 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Inhibition of hepatitis C virus replication by antimonial compounds
Hwang, DR, Lin, RK, Leu, GZ, Lin, TY, Lien, TW, Yu, MC, Yeh, CT, and Hsu, JT
Antimicrob Agents Chemother 2005. 49(10): 4197-202
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16189098&dopt=abstract
15. 57902 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Neuraminidase inhibitor-resistant influenza viruses may differ substantially in fitness and transmissibility
Yen, HL, Herlocher, LM, Hoffmann, E, Matrosovich, MN, Monto, AS, Webster, RG, and Govorkova, EA
Antimicrob Agents Chemother 2005. 49(10): 4075-84
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16189083&dopt=abstract
16. 57903 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
Preparation of nucleosides as prodrugs and antiviral agents
Roberts, Christopher D, Keicher, Jesse D, and Dyatkina, Natalia B
PATENT: US 20050215511 ISSUE DATE: 20050929
APPLICATION: 2004-53973 PP: 58 pp., Cont.-in-part of U.S. Ser. No. 861,311.
ASSIGNEE: (Genelabs Technologies, Inc. USA
17. 57904 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
Methods for preparing 7-(2'-substituted-b-D-ribofuranosyl)-4-(NR2R3)-5-(substituted ethyn-1-yl)-pyrrolo[2,3-d]pyrimidine derivatives as antiviral agents
Roberts, Christopher D, Keicher, Jesse D, and Dyatkina, Natalia B
PATENT: US 20050215510 ISSUE DATE: 20050929
APPLICATION: 2004-53137 PP: 28 pp., Cont.-in-part of U.S. Ser. No. 861,311.
ASSIGNEE: (Genelabs Technologies, Inc. USA
18. 57905 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
An orally bioavailable antipoxvirus compound (ST-246) inhibits extracellular virus formation and protects mice from lethal orthopoxvirus Challenge
Yang, G, Pevear, DC, Davies, MH, Collett, MS, Bailey, T, Rippen, S, Barone, L, Burns, C, Rhodes, G, Tohan, S, Huggins, JW, Baker, RO, Buller, RL, Touchette, E, Waller, K, Schriewer, J, Neyts, J, DeClercq, E, Jones, K, Hruby, D, and Jordan, R
J Virol 2005. 79(20): 13139-49
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16189015&dopt=abstract
19. 57906 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
Use of heterogeneous nuclear ribonucleoprotein K to inhibit the replication of hepatitis viruses B and C by binding to cis-regulatory elements
Poh, Lisa Ng Fong and Ren, Ee Chee
PATENT: WO 2005059138 ISSUE DATE: 20050630
APPLICATION: 2004 PP: 82 pp.
ASSIGNEE: (Agency for Science, Technology and Research Singapore
20. 57907 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Binding-site characterization and resistance to a class of non-nucleoside inhibitors of the HCV NS5B polymerase
Kukolj, G, McGibbon, GA, McKercher, G, Marquis, M, Lefebvre, S, Thauvette, L, Gauthier, J, Goulet, S, Poupart, MA, and Beaulieu, PL
J Biol Chem 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16188890&dopt=abstract
21. 57908 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Human cytomegalovirus-inhibitory flavonoids: Studies on antiviral activity and mechanism of action
Evers, DL, Chao, CF, Wang, X, Zhang, Z, Huong, SM, and Huang, ES
Antiviral Res 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16188329&dopt=abstract
22. 57909 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Ectromelia virus: the causative agent of mousepox
Esteban, DJ and Buller, RM
J Gen Virol 2005. 86(Pt 10): 2645-59
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16186218&dopt=abstract
23. 57910 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
Preparation of phosphonated isoxazolidinyl nucleoside analogs with antiviral activity
Chiacchio, Ugo, Corsaro, Antonino, Iannazzo, Daniela, Macchi, Beatrice, Mastino, Antonio, Piperno, Anna, Rescifina, Antonio, Romeo, Giovanni, and Romeo, Roberto
PATENT: WO 2005082896 ISSUE DATE: 20050909
APPLICATION: 2005 PP: 29 pp.
ASSIGNEE: (Universita' Degli Studi di Catania, Italy and Universita' Degli Studi di Messina)
24. 57911 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
High-Throughput Cell-Based Screening for Hepatitis C Virus NS3/4A Protease Inhibitors
Lee, JC, Yu, MC, Lien, TW, Chang, CF, and Hsu, JT
Assay Drug Dev Technol 2005. 3(4): 385-392
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16180993&dopt=abstract
25. 57912 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
New approaches and therapeutic modalities for the treatment of patients with chronic hepatitis C
Cornberg, M and Manns, MP
Ann Hepatol 2005. 4(3): 144-50
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16177653&dopt=abstract
26. 57913 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
4-Oxo-4,7-dihydrothieno[2,3-b]pyridines as Non-Nucleoside Inhibitors of Human Cytomegalovirus and Related Herpesvirus Polymerases
Schnute, Mark E, Cudahy, Michele M, Brideau, Roger J, Homa, Fred L, Hopkins, Todd A, Knechtel, Mary L, Oien, Nancee L, Pitts, Thomas W, Poorman, Roger A, Wathen, Michael W, and Wieber, Janet L
Journal of Medicinal Chemistry 2005. 48(18): 5794-5804
27. 57914 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Both antigen optimization and lysosomal targeting are required for enhanced anti-tumour protective immunity in a human papillomavirus E7-expressing animal tumour model
Kim, MS and Sin, JI
Immunology 2005. 116(2): 255-66
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16162274&dopt=abstract
28. 57915 DMID-LS-103; PUBMED-DMID-10/11/2005 ; DMID-LSLOAD
Capsid-targeted viral inactivation can destroy dengue 2 virus from within in vitro
Qin, CF and Qin, ED
Arch Virol 2005.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16155726&dopt=abstract
29. 57916 DMID-LS-103; WOS-DMID-10/11/2005 ; DMID-LSLOAD
Potential Impact of Antiviral Drug Use During Influenza Pandemic
Gani, R. et al.
Emerging Infectious Diseases 2005. 11(9): 1355-1362
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000231591400004
30. 57917 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
Cytotoxicity and antiviral activity of a lignan extracted from Larrea divaricata
Konigheim, BS, Goleniowski, ME, and Contigiani, MS
Drug Design Reviews--Online 2005. 2(1): 81-83
31. 57918 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
Studies on the antiviral and cytotoxic activity of Schiff bases derived from 1,2-bis-(o- and p-aminophenoxy)ethane and salicylaldehyde
Bulut, Hakan, Karatepe, Mustafa, Temel, Hamdi, Sekerc, Memet, and Koparir, Metin
Asian Journal of Chemistry 2005. 17(4): 2793-2796
32. 57919 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
Screening of antiviral drugs, and pharmaceutical compositions containing 2-thioxothiazolidinone derivatives
Gregor, Paul, Harris, Nicholas, and Zhuk, Regina
PATENT: WO 2005089067 ISSUE DATE: 20050929
APPLICATION: 2005 PP: 52 pp.
ASSIGNEE: (Rimonyx Pharmaceuticals Ltd., Israel
33. 57920 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
CycloSal-pronucleotides of brivudine monophosphate - highly active antiviral agents
Meier, Chris, Meerbach, Astrid, and Wutzler, Peter
Current Medicinal Chemistry: Anti-Infective Agents 2005. 4(4): 317-335
34. 57921 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
Antiviral agents from traditional Chinese medicine against herpes simplex virus
Cheng, Chuen-Lung and Xu, Hong-Xi
Journal of Traditional Medicines 2005. 22(Suppl. 1): 133-137
35. 57922 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
Antiviral compositions comprising CCL5 (RANTES) fragments or mimetics, or CC chemokine receptor antagonists for inhibiting paramyxovirus infection
Hancock, Gerald Ervin and Tebbey, Paul William
PATENT: WO 2005066205 ISSUE DATE: 20050721
APPLICATION: 2004 PP: 82 pp.
ASSIGNEE: (Wyeth, John and Brother Ltd. USA
36. 57923 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
Synthesis of N4-substituted derivatives of (S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (HPMPC, cidofovir, vistide)
Chalupova, Sarka and Holy, Antonin
Collection Symposium Series 2005. 7(Chemistry of Nucleic Acid Components): 387-388
37. 57924 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
Phosphonates, monophosphonamidates, bisphosphonamidates for the treatment of viral diseases
Cheng, Xiaqin, Cook, Gary P, Desai, Manoj C, Doerffler, Edward, He, Gong-Xin, Kim, Choung U, Lee, William A, Rohloff, John C, Wang, Jianying, and Yang, Zheng-Yu
PATENT: WO 2005066189 ISSUE DATE: 20050721
APPLICATION: 2004 PP: 161 pp.
ASSIGNEE: (Gilead Sciences, Inc. USA
38. 57925 DMID-LS-103; SCIFINDER-DMID-10/11/2005 ; DMID-LSLOAD
Murine polyomavirus-VP1 virus-like particles immunize against some polyomavirus-induced tumors
Franzen, Andrea Vlastos, Tegersted, Karin, Hollaenderova, Dana, Forstova, Jitka, Ramqvist, Torbjoern, and Dalianis, Tina
In Vivo 2005. 19(2): 323-326