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ONLINE DATABASE SEARCH - OI-LS-354-MEMO

1. 49257 OI-LS-354; PUBMED-OI-8/7/2006

Bleomycin is a Potent Small-Molecule Inhibitor of Hepatitis C Virus Replication

Rakic, B, Brulotte, M, Rouleau, Y, Belanger, S, and Pezacki, JP

Chembiochem 2006.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16888741&dopt=abstract


2. 49258 OI-LS-354; EMBASE-OI-8/7/2006

Understanding the action of INH on a highly INH-resistant Mycobacterium tuberculosis strain using Genechips

Fu, Li M and Shinnick, Thomas M

Tuberculosis 2006. In Press, Corrected Proof


HYPERLINK:

http://www.sciencedirect.com/science/article/B6WXK-4KJDWYW-1/2/a7effe9ed0e2dcea2d1ca6b1eb0590db


3. 49259 OI-LS-354; PUBMED-OI-8/7/2006

Antimycobacterial Agents. Novel Diarylpyrrole Derivatives of BM212 Endowed with High Activity toward Mycobacterium tuberculosis and Low Cytotoxicity

Biava, M, Porretta, GC, Poce, G, Supino, S, Deidda, D, Pompei, R, Molicotti, P, Manetti, F, and Botta, M

J Med Chem 2006. 49(16): 4946-4952


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16884306&dopt=abstract


4. 49260 OI-LS-354; PUBMED-OI-8/7/2006

Brunsvicamides A-C: Sponge-Related Cyanobacterial Peptides with Mycobacteriumtuberculosis Protein Tyrosine Phosphatase Inhibitory Activity

Muller, D, Krick, A, Kehraus, S, Mehner, C, Hart, M, Kupper, FC, Saxena, K, Prinz, H, Schwalbe, H, Janning, P, Waldmann, H, and Konig, GM

J Med Chem 2006. 49(16): 4871-4878


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16884299&dopt=abstract


5. 49261 OI-LS-354; EMBASE-OI-8/7/2006

Intracellular growth and drug susceptibility of Mycobacterium tuberculosis in macrophages

Chanwong, Sakarin, Maneekarn, Niwat, Makonkawkeyoon, Luksana, and Makonkawkeyoon, Sanit

Tuberculosis 2006. In Press, Corrected Proof


HYPERLINK:

http://www.sciencedirect.com/science/article/B6WXK-4KFV3G2-1/2/614fc58c7859f21d4d88572f27ab7a95



6. 49262 OI-LS-354; PUBMED-OI-8/7/2006

Drug resistance in Mycobacterium tuberculosis

Johnson, R, Streicher, EM, Louw, GE, Warren, RM, van, Helden PD, and Victor, TC

Curr Issues Mol Biol 2006. 8(2): 97-111


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16878362&dopt=abstract


7. 49263 OI-LS-354; EMBASE-OI-8/7/2006

Entry and intracellular replication of Mycobacterium tuberculosis in cultured human microvascular endothelial cells

Mehta, Parmod K, Karls, Russell K, White, Elizabeth H, Ades, Edwin W, and Quinn, Frederick D

Microbial Pathogenesis 2006. In Press, Corrected Proof


HYPERLINK:

http://www.sciencedirect.com/science/article/B6WN6-4KGG1NV-1/2/f5946d360a8956e521b6c81ba5cad854


8. 49264 OI-LS-354; PUBMED-OI-8/7/2006

Recruitment of an interferon molecular signaling complex to the mitochondrial membrane: Disruption by hepatitis C virus NS3-4A protease

Hiscott, J, Lacoste, J, and Lin, R

Biochem Pharmacol 2006.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16876765&dopt=abstract


9. 49265 OI-LS-354; EMBASE-OI-8/7/2006

Serine palmitoyltransferase inhibitor suppresses HCV replication in a mouse model

Umehara, Takuya, Sudoh, Masayuki, Yasui, Fumihiko, Matsuda, Chiho, Hayashi, Yukiko, Chayama, Kazuaki, and Kohara, Michinori

Biochemical and Biophysical Research Communications 2006. 346(1): 67-73


HYPERLINK:

http://www.sciencedirect.com/science/article/B6WBK-4K1G451-5/2/717388dac90a0b82815d00acf5b891d2


10. 49266 OI-LS-354; PUBMED-OI-8/7/2006

Symmetrical and unsymmetrical analogues of isoxyl; active agents against Mycobacterium tuberculosis

Bhowruth, V, Brown, AK, Reynolds, RC, Coxon, GD, Mackay, SP, Minnikin, DE, and Besra, GS

Bioorg Med Chem Lett 2006.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16875817&dopt=abstract



11. 49267 OI-LS-354; PUBMED-OI-8/7/2006

Crystal Structure and Activity Studies of the Mycobacterium tuberculosis {beta}-Lactamase Reveal Its Critical Role in Resistance to {beta}-Lactam Antibiotics

Wang, F, Cassidy, C, and Sacchettini, JC

Antimicrob Agents Chemother 2006. 50(8): 2762-71


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16870770&dopt=abstract


12. 49268 OI-LS-354; EMBASE-OI-8/7/2006

Gatifloxacin derivatives: Synthesis, antimycobacterial activities, and inhibition of Mycobacterium tuberculosis DNA gyrase

Sriram, Dharmarajan, Aubry, Alexandra, Yogeeswari, Perumal, and Fisher, LM

Bioorganic & Medicinal Chemistry Letters 2006. 16(11): 2982-2985


HYPERLINK:

http://www.sciencedirect.com/science/article/B6TF9-4JJ2BJM-2/2/27d1f9018ac921fd3763b08fdf29ceb7


13. 49269 OI-LS-354; PUBMED-OI-8/7/2006

Combination Chemotherapy with the Nitroimidazopyran PA-824 and First-Line Drugs in a Murine Model of Tuberculosis

Nuermberger, E, Rosenthal, I, Tyagi, S, Williams, KN, Almeida, D, Peloquin, CA, Bishai, WR, and Grosset, JH

Antimicrob Agents Chemother 2006. 50(8): 2621-5


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16870750&dopt=abstract


14. 49270 OI-LS-354; EMBASE-OI-8/7/2006

Crystallographic and Pre-steady-state Kinetics Studies on Binding of NADH to Wild-type and Isoniazid-resistant Enoyl-ACP(CoA) Reductase Enzymes from Mycobacterium tuberculosis

Oliveira, Jaim S, Pereira, Jose H, Canduri, Fernanda, Rodrigues, Nathalia C, de Souza, Osmar N, de Azevedo, Jr Walter F, Basso, Luiz A, and Santos, Diogenes S

Journal of Molecular Biology 2006. 359(3): 646-666


HYPERLINK:

http://www.sciencedirect.com/science/article/B6WK7-4JSG6FC-1/2/1b662ac95819caeaf7d73a5fb4965c4f


15. 49271 OI-LS-354; EMBASE-OI-8/7/2006

Synthesis, in vitro and in vivo antimycobacterial activities of diclofenac acid hydrazones and amides

Sriram, Dharmarajan, Yogeeswari, Perumal, and Devakaram, Ruth Vandana

Bioorganic & Medicinal Chemistry 2006. 14(9): 3113-3118


HYPERLINK:

http://www.sciencedirect.com/science/article/B6TF8-4J2KT9Y-7/2/3eb87cefe86b1239c68810c8ce3f85b9



16. 49272 OI-LS-354; PUBMED-OI-8/7/2006

Functional characterization of a fatty acyl-CoA-binding protein (ACBP) from the apicomplexan Cryptosporidium parvum

Zeng, B, Cai, X, and Zhu, G

Microbiology 2006. 152(Pt 8): 2355-63


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16849800&dopt=abstract


17. 49273 OI-LS-354; EMBASE-OI-8/7/2006

Enhanced susceptibility of multidrug resistant strains of Mycobacterium tuberculosis to granulysin peptides correlates with a reduced fitness phenotype

Toro, Juan Carlos, Hoffner, Sven, Linde, Charlotte, Andersson, Mats, Andersson, Jan, and Grundstrom, Susanna

Microbes and Infection 2006. In Press, Corrected Proof


HYPERLINK:

http://www.sciencedirect.com/science/article/B6VPN-4K3CXST-1/2/c024fd5a6120d48a8109b81bfea7f6b0


18. 49274 OI-LS-354; EMBASE-OI-8/7/2006

Synthesis of pyrazinamide Mannich bases and its antitubercular properties

Sriram, Dharmarajan, Yogeeswari, Perumal, and Reddy, Sushma Pobba

Bioorganic & Medicinal Chemistry Letters 2006. 16(8): 2113-2116


HYPERLINK:

http://www.sciencedirect.com/science/article/B6TF9-4J6X3N2-7/2/b1717482dd482fe09bd8dfa6c1620723


19. 49275 OI-LS-354; EMBASE-OI-8/7/2006

l-Nucleoside enantiomers as antivirals drugs: A mini-review

Mathe, Christophe and Gosselin, Gilles

Antiviral Research 2006. In Press, Corrected Proof


HYPERLINK:

http://www.sciencedirect.com/science/article/B6T2H-4K18TKC-1/2/7c9e5bd48ebba0d36b3d74cfefe3a1b1


20. 49276 OI-LS-354; EMBASE-OI-8/7/2006

Ileabethoxazole: a novel benzoxazole alkaloid with antimycobacterial activity

Rodriguez, Ileana I, Rodriguez, Abimael D, Wang, Yuehong, and Franzblau, Scott G

Tetrahedron Letters 2006. 47(19): 3229-3232


HYPERLINK:

http://www.sciencedirect.com/science/article/B6THS-4JJGB0S-B/2/736d60a19fe2382b77e00eafa6c30c04


21. 49277 OI-LS-354; PUBMED-OI-8/7/2006

Toxoplasma gondii purine nucleoside phosphorylase: Biochemical characterization, inhibitor profiles and comparison with the plasmodium falciparum ortholog

Chaudhary, K, Ting, LM, Kim, K, and Roos, DS

J Biol Chem 2006.


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16829527&dopt=abstract


22. 49278 OI-LS-354; PUBMED-OI-8/7/2006

Avian influenza (H5N1)--the next pandemic?

Rivera, SJ

Imprint 2006. 53(3): 56, 58, 62


HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16821532&dopt=abstract


23. 49279 OI-LS-354; WOS-OI-7/30/2006

Synthesis of the antimycobacterial naphthoquinone, 7-methyljuglone and its dimer, neodiospyrin

van der Kooy, F and Meyer, JJM

SOUTH AFRICAN JOURNAL OF CHEMISTRY-SUID-AFRIKAANSE TYDSKRIF VIR CHEMIE 2006. 59: 60-61, 2


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000239036100006


24. 49280 OI-LS-354; WOS-OI-7/30/2006

Nonstructural protein 5B of hepatitis C virus

Lee, JH, Nam, IY, and Myung, H

MOLECULES AND CELLS 2006. 21(3): 330-336, 7


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000238843800002


25. 49281 OI-LS-354; WOS-OI-7/30/2006

Substituted pyrazinecarboxamides: Synthesis and biological evaluation

Dolezal, M, Palek, L, Vinsova, J, Buchta, V, Jampilek, J, and Kralova, K

MOLECULES 2006. 11(4): 242-256, 15


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000238940100003


26. 49282 OI-LS-354; EMBASE-OI-8/7/2006

Beyond interferon and ribavirin: Antiviral therapies for hepatitis C virus

Kwong, Ann D, Cowherd, Sarah, and Mueller, Peter

Drug Discovery Today: Therapeutic Strategies 2006. In Press, Corrected Proof


HYPERLINK:

http://www.sciencedirect.com/science/article/B75D9-4KDBM66-1/2/fb3ffcdd0bbbbd02b81f49fe622a6504


27. 49283 OI-LS-354; EMBASE-OI-8/7/2006

Hepatotoxicity of antiretrovirals: Incidence, mechanisms and management: Proceedings of the 1st European Consensus Conference on the Treatment of Chronic Hepatitis B and C in HIV Co-infected Patients

Nunez, Marina

Journal of Hepatology 2006. 44(Supplement 1): S132-S139


HYPERLINK:

http://www.sciencedirect.com/science/article/B6W7C-4HNSR78-4/2/022d47488fc89c044da925b95bf8eef0



28. 49284 OI-LS-354; WOS-OI-7/30/2006

Model-based drug development: The road to quantitative pharmacology

Zhang, LP, Sinha, V, Forgue, ST, Callies, S, Ni, L, Peck, R, and Allerheiligen, SRB

JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS 2006. 33(3): 369-393, 25


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000238862600006


29. 49285 OI-LS-354; EMBASE-OI-8/7/2006

78 The HCV NS3 protease inhibitor SCH 503034 in combination with PEG-IFN[alpha]-2b in the treatment of HCV-1 PEG-IFN[alpha]-2b non-responders: Antiviral activity and HCV variant analysis

Zeuzem, S, Sarrazin, C, Wagner, F, Rouzier, R, Forestier, N, Gupta, S, Hussain, M, Shah, A, Cutler, D, and Zhang, J

Journal of Hepatology 2006. 44(Supplement 2): S35


HYPERLINK:

http://www.sciencedirect.com/science/article/B6W7C-4KCHKWH-2T/2/2f9b986834323c0fa308d59c6d83c51a


30. 49286 OI-LS-354; EMBASE-OI-8/7/2006

Search for antibacterial and antifungal agents from selected Indian medicinal plants

Kumar, VPrashanth, Chauhan, Neelam S, Padh, Harish, and Rajani, M

Journal of Ethnopharmacology 2006. In Press, Corrected Proof


HYPERLINK:

http://www.sciencedirect.com/science/article/B6T8D-4JK4DBM-1/2/be6e3a8abfc0d9dc30fc89af604399fb


31. 49287 OI-LS-354; EMBASE-OI-8/7/2006

Microwave-assisted synthesis of antimicrobial dihydropyridines and tetrahydropyrimidin-2-ones: Novel compounds against aspergillosis

Chhillar, Anil K, Arya, Pragya, Mukherjee, Chandrani, Kumar, Pankaj, Yadav, Yogesh, Sharma, Ajendra K, Yadav, Vibha, Gupta, Jyotsana, Dabur, Rajesh, and Jha, Hirday N

Bioorganic & Medicinal Chemistry 2006. 14(4): 973-981


HYPERLINK:

http://www.sciencedirect.com/science/article/B6TF8-4H8MNSK-D/2/116a4c3eedde1edf0b37f23a70923f6a


32. 49288 OI-LS-354; WOS-OI-7/30/2006

Crystal structure of Mycobacterium tuberculosis shikimate kinase in complex with shikimic acid and an ATP analogue

Gan, JH, Gu, YJ, Li, Y, Yan, HG, and Ji, XH

BIOCHEMISTRY 2006. 45(28): 8539-8545, 7


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000238924600009


33. 49289 OI-LS-354; WOS-OI-8/6/2006

Development of a synthetic process towards a hepatitis C polymerase inhibitor

Camp, D, Matthews, CF, Neville, ST, Rouns, M, Scott, RW, and Truong, Y

ORGANIC PROCESS RESEARCH & DEVELOPMENT 2006. 10(4): 814-821, 8


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000239167500018



34. 49290 OI-LS-354; WOS-OI-8/6/2006

Designing better drugs: predicting cytochrome P450 metabolism

de Groot, MJ

DRUG DISCOVERY TODAY 2006. 11(13-14): 601-606, 6


HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000239081100005


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