ONLINE DATABASE SEARCH - OI-LS-343-MEMO
1. 48565 OI-LS-343; PUBMED-OI-3/6/2006
Pyranocoumarin, a novel anti-TB pharmacophore: Synthesis and biological evaluation against Mycobacterium tuberculosis
Xu, ZQ, Pupek, K, Suling, WJ, Enache, L, and Flavin, MT
Bioorg Med Chem 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16513358&dopt=abstract
2. 48566 OI-LS-343; PUBMED-OI-3/6/2006
Telbivudine: A Novel Nucleoside Analog for Chronic Hepatitis B (March)
Kim, JW, Park, SH, and Louie, SG
Ann Pharmacother 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16507625&dopt=abstract
3. 48567 OI-LS-343; SCIFINDER-OI-2/27/2006
Effects of albendazole, fumagillin, and TNP-470 on microsporidial replication in vitro
Didier, Elizabeth S
Antimicrobial Agents and Chemotherapy 1997. 41(7): 1541-1546
4. 48568 OI-LS-343; PUBMED-OI-3/6/2006
The crystal structure of Rv0793, a hypothetical monooxygenase from M. tuberculosis
Lemieux, MJ, Ference, C, Cherney, MM, Wang, M, Garen, C, and James, MN
J Struct Funct Genomics 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16496224&dopt=abstract
5. 48569 OI-LS-343; SCIFINDER-OI-2/27/2006
Water-soluble amphotericin B-polyvinylpyrrolidone complexes with maintained antifungal activity against Candida spp. and Aspergillus spp. and reduced haemolytic and cytotoxic effects
Charvalos, Ekatherina, Tzatzarakis, Manolis N, Van Bambeke, Francoise, Tulkens, Paul M, Tsatsakis, Aristidis M, Tzanakakis, George N, and Mingeot-Leclercq, Marie-Paule
Journal of Antimicrobial Chemotherapy 2006. 57(2): 236-244
6. 48570 OI-LS-343; SCIFINDER-OI-2/27/2006
Preparation of arylamidine derivatives as antifungal agents
Hayashi, Kazuya, Kunitani, Kazuto, Uehara, Sayuri, and Morita, Teiichi
PATENT: WO 2006003881 ISSUE DATE: 20060112
APPLICATION: 2005 PP: 85 pp.
ASSIGNEE: (Toyama Chemical Co., Ltd. Japan
7. 48571 OI-LS-343; PUBMED-OI-3/6/2006
Potent Inhibition of Macrophage Responses to IFN-{gamma} by Live Virulent Mycobacterium tuberculosis Is Independent of Mature Mycobacterial Lipoproteins but Dependent on TLR2
Banaiee, N, Kincaid, EZ, Buchwald, U, Jacobs, WR Jr, and Ernst, JD
J Immunol 2006. 176(5): 3019-27
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16493060&dopt=abstract
8. 48572 OI-LS-343; PUBMED-OI-3/6/2006
Structure-based inhibitor design of AccD5, an essential acyl-CoA carboxylase carboxyltransferase domain of Mycobacterium tuberculosis
Lin, TW, Melgar, MM, Kurth, D, Swamidass, SJ, Purdon, J, Tseng, T, Gago, G, Baldi, P, Gramajo, H, and Tsai, SC
Proc Natl Acad Sci U S A 2006.
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16492739&dopt=abstract
9. 48573 OI-LS-343; PUBMED-OI-3/6/2006
Selective anti-cytomegalovirus compounds discovered by screening for inhibitors of subunit interactions of the viral polymerase
Loregian, A and Coen, DM
Chem Biol 2006. 13(2): 191-200
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16492567&dopt=abstract
10. 48574 OI-LS-343; PUBMED-OI-3/6/2006
Synthesis and antimicrobial activity of some new 1-alkyl-2-alkylthio-1,2,4-triazolobenzimidazole derivatives
Mohamed, BG, Hussein, MA, Abdel-Alim, AA, and Hashem, M
Arch Pharm Res 2006. 29(1): 26-33
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16491839&dopt=abstract
11. 48575 OI-LS-343; SCIFINDER-OI-2/27/2006
Antibacterial and antifungal ferrocene incorporated dithiothione and dithioketone compounds
Chohan, Zahid H
Applied Organometallic Chemistry 2006. 20(2): 112-116
12. 48576 OI-LS-343; SCIFINDER-OI-2/27/2006
Hydroxylated analogues of the orally active broad spectrum antifungal, Sch 51048, and the discovery of posaconazole (Sch 56592)
Bennett, Frank, Saksena, Anil K, Lovey, Raymond G, Liu, Yi-Tsung, Patel, Naginbhai M, Pinto, Patrick, Pike, Russel, Jao, Edwin, Girijavallabhan, Viyyoor M, Ganguly, Ashit K, Loebenberg, David, Wang, Haiyan, Cacciapuoti, Anthony, Moss, Eugene, Menzel, Fred, Hare, Roberta S, and Nomeir, Amin
Bioorganic & Medicinal Chemistry Letters 2006. 16(1): 186-190
13. 48577 OI-LS-343; SCIFINDER-OI-2/27/2006
Aerosolised antibiotics: a critical appraisal of their use
Hagerman, Jennifer K, Hancock, Kim E, and Klepser, Michael E
Expert Opinion on Drug Delivery 2006. 3(1): 71-86
14. 48578 OI-LS-343; SCIFINDER-OI-2/27/2006
Oxazolidinone derivatives as antimicrobials
Das Biswajit, Ahmed, Shahadat, Yadav, Ajay Singh, Ghosh, Soma, and Rattan, Ashok
PATENT: WO 2006018682 ISSUE DATE: 20060223
APPLICATION: 2005
ASSIGNEE: (Ranbaxy Laboratories Limited, India
15. 48579 OI-LS-343; WOS-OI-2/26/2006
Genomic analysis of the Mycobacterium tuberculosis complex: applications to laboratory diagnosis and genotyping
Driscoll, JR, Parsons, LA, Salfinger, M, and Taber, HW
REVIEWS IN MEDICAL MICROBIOLOGY 2005. 16(2): 49-58, 10
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235223400003
16. 48580 OI-LS-343; SCIFINDER-OI-2/27/2006
Methods of screening for inhibitors of m. tuberculosis, assays for use therein, and methods and compositions for treating of preventing m. tuberculosis infection
Derbyshire, Keith M and Kowalski, Joseph C
PATENT: WO 2006020898 ISSUE DATE: 20060223
APPLICATION: 2005
ASSIGNEE: (Health Research, Inc. USA
17. 48581 OI-LS-343; SCIFINDER-OI-2/27/2006
Characterization of the putative operon containing arylamine N-acetyltransferase (nat) in Mycobacterium bovis BCG
Anderton, Matthew C, Bhakta, Sanjib, Besra, Gurdyal S, Jeavons, Peter, Eltis, Lindsay D, and Sim, Edith
Molecular Microbiology 2006. 59(1): 181-192
18. 48582 OI-LS-343; SCIFINDER-OI-2/27/2006
High Affinity InhA Inhibitors with Activity against Drug-Resistant Strains of Mycobacterium tuberculosis
Sullivan, Todd J, Truglio, James J, Boyne, Melissa E, Novichenok, Polina, Zhang, Xujie, Stratton, Christopher F, Li, Huei-Jiun, Kaur, Tejinder, Amin, Amol, Johnson, Francis, Slayden, Richard A, Kisker, Caroline, and Tonge, Peter J
ACS Chemical Biology 2006. 1(1): 43-53
19. 48583 OI-LS-343; SCIFINDER-OI-2/27/2006
Pyridinylamines and their preparations, pharmaceutical compositions and use for prophylaxis or treatment of various diseases
Eickhoff, Jan Eike, Hafenbradl, Doris, Schwab, Wilfried, Cotton, Matthew, Klebl, Bert Matthias, Zech, Birgit, Mueller, Stefan, Harris, John, Savic, Vladimir, Macritchie, Jackie, Sherborne, Brad, and Le, Joelle
PATENT: WO 2006010637 ISSUE DATE: 20060202
APPLICATION: 2005 PP: 177 pp.
ASSIGNEE: (Gpc Biotech AG, Germany
20. 48584 OI-LS-343; SCIFINDER-OI-2/27/2006
Concurrent antiviral and immunosuppressive activities of leflunomide in vivo
Chong, AS, Zeng, H, Knight, DA, Shen, J, Meister, GT, Williams, JW, and Waldman, WJ
American Journal of Transplantation 2006. 6(1): 69-75
21. 48585 OI-LS-343; SCIFINDER-OI-2/27/2006
Antiviral methods and compositions
Coen, Donald M and Loregian, Arianna
PATENT: WO 2006019955 ISSUE DATE: 20060223
APPLICATION: 2005
ASSIGNEE: (President and Fellows of Harvard College, USA
22. 48586 OI-LS-343; SCIFINDER-OI-2/27/2006
Synthesis and screening of bicyclic carbohydrate-based compounds: A novel type of antivirals
Van Hoof, Steven, Ruttens, Bart, Hubrecht, Idzi, Smans, Gert, Blom, Petra, Sas, Benedikt, Van Hemel, Johan, Vandenkerckhove, Jan, and Van der Eycken, Johan
Bioorganic & Medicinal Chemistry Letters 2006. 16(6): 1495-1498
23. 48587 OI-LS-343; SCIFINDER-OI-2/27/2006
Agents with leukotriene B4-like antiviral (enveloped RNA) activities
Gosselin, Jean and Borgeat, Pierre
PATENT: US 2006025479 ISSUE DATE: 20060202
APPLICATION: 2004-11016 PP: 28 pp., Cont.-in-part of U.S. Ser. No. 683,882, abandoned.
ASSIGNEE: (Can.)
24. 48588 OI-LS-343; SCIFINDER-OI-2/27/2006
Synthesis and Antiviral Evaluation of Cyclic and Acyclic 2-Methyl-3-hydroxy-4-pyridinone Nucleoside Derivatives
Barral, Karine, Balzarini, Jan, Neyts, Johan, De Clercq, Erik, Hider, Robert C, and Camplo, Michel
Journal of Medicinal Chemistry 2006. 49(1): 43-50
25. 48589 OI-LS-343; SCIFINDER-OI-2/27/2006
N-Substituted-sulfamoylbenzoic acid derivatives, particularly 4-[N-[4-(4-morpholino)phenyl]sulfamoyl]benzoic acid derivatives, method for preparing them, and antiviral pharmaceutical compositions comprising them, for treatment of hepatitis C virus infection
Kim, Jong Woo, Lee, Sang Wook, Lee, Geun Hyung, Han, Jae Jin, Park, Sang Jin, Park, Eul Yong, and Shin, Joong Chul
PATENT: WO 2006011719 ISSUE DATE: 20060202
APPLICATION: 2005 PP: 20 pp.
ASSIGNEE: (B & C Biopharm Co., Ltd. S. Korea
26. 48590 OI-LS-343; SCIFINDER-OI-2/27/2006
2-(2-Thienyl)-5,6-dihydroxy-4-carboxypyrimidines as Inhibitors of the Hepatitis C Virus NS5B Polymerase: Discovery, SAR, Modeling, and Mutagenesis
Koch, Uwe, Attenni, Barbara, Malancona, Savina, Colarusso, Stefania, Conte, Immacolata, Di Filippo, Marcello, Harper, Steven, Pacini, Barbara, Giomini, Claudia, Thomas, Steven, Incitti, Ilario, Tomei, Licia, De Francesco, Raffaele, Altamura, Sergio, Matassa, Victor G, and Narjes, Frank
Journal of Medicinal Chemistry 2006. 49(5): 1693-1705
27. 48591 OI-LS-343; SCIFINDER-OI-2/27/2006
Preparation of peptide analogs as hepatitis C inhibitors
Bailey, Murray D, Bhardwaj, Punit, Ghiro, Elise, Goudreau, Nathalie, Halmos, Teddy, Llinas-Brunet, Montse, Poupart, Marc-Andre, and Rancourt, Jean
PATENT: WO 2006007708 ISSUE DATE: 20060126
APPLICATION: 2005 PP: 112 pp.
ASSIGNEE: (Boehringer Engelheim International GmbH, Germany and Boehringer Ingelheim Pharma Gmbh & Co KG)
28. 48592 OI-LS-343; SCIFINDER-OI-2/27/2006
Fused imidazole and thiazole derivatives as antiviral agents, their preparation, pharmaceutical compositions, and use for inhibiting hepatitis C virus polymerase
Conte, Immacolata, Hernando, Jose Ignacio Martin, Malancona, Savina, Ontoria Ontoria, Jesus Maria, and Stansfield, Ian
PATENT: WO 2006008556 ISSUE DATE: 20060126
APPLICATION: 2005 PP: 34 pp.
ASSIGNEE: (Istituto di Ricerche di Biologia Molecolare P. Angeletti SpA, Italy
29. 48593 OI-LS-343; SCIFINDER-OI-2/27/2006
Heterocyclic antiviral compounds
Blake, James F, Fell, Jay Bradford, Fischer, John P, Hendricks, Robert Than, Robinson, John E, Spencer, Stacey Renee, and Stengel, Peter J
PATENT: US 2006040927 ISSUE DATE: 20060223
APPLICATION: 2005-12354 PP: 50 pp., which
ASSIGNEE: (Roche Palo Alto LLC, USA
30. 48594 OI-LS-343; SCIFINDER-OI-2/27/2006
Anti-viral nucleosides
Martin, Joseph Armstrong, Sarma, Keshab, and Smith, David Bernard
PATENT: US 2006040890 ISSUE DATE: 20060223
APPLICATION: 2005-11902 PP: 22 pp.
ASSIGNEE: (Roche Palo Alto LLC, USA
31. 48595 OI-LS-343; SCIFINDER-OI-2/27/2006
Cyanoacetic acid hydrazones of 3-(and 4-)acetylpyridine and some derived ring systems as potential antitumor and anti-HCV agents
El-Hawash, Soad AM, Abdel Wahab, Abeer E, and El-Demellawy, Maha A
Archiv der Pharmazie (Weinheim, Germany) 2006. 339(1): 14-23
32. 48596 OI-LS-343; SCIFINDER-OI-2/27/2006
Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidine and purine nucleoside analogs via condensation of the lactone to nucleosides as potential antiviral agents
Wang, Peiyuan, Stec, Wojciech, Clark, Jeremy, Chun, Byoung-Kwon, Shi, Junxing, and Du, Jinfa
PATENT: WO 2006012440 ISSUE DATE: 20060202
APPLICATION: 2005 PP: 34 pp.
ASSIGNEE: (Pharmasset, Inc. USA
33. 48597 OI-LS-343; SCIFINDER-OI-2/27/2006
Preparation of nucleoside aryl phosphoramidates for use as an inhibitor of hepatitis C virus NS5B polymerase, RNA-dependent RNA polymerase, RNA viral replication and treating RNA-dependent RNA viral infections
Maccoss, Malcolm and Olsen, David B
PATENT: WO 2006012078 ISSUE DATE: 20060202
APPLICATION: 2005 PP: 40 pp.
ASSIGNEE: (Merck & Co., Inc. USA
34. 48598 OI-LS-343; SCIFINDER-OI-2/27/2006
Exploration of acyl sulfonamides as carboxylic acid replacements in protease inhibitors of the hepatitis C virus full-length NS3
Roenn, Robert, Sabnis, Yogesh A, Gossas, Thomas, Aakerblom, Eva, Danielson, UHelena, Hallberg, Anders, and Johansson, Anja
Bioorganic & Medicinal Chemistry 2006. 14(2): 544-559
35. 48599 OI-LS-343; WOS-OI-2/26/2006
Fluoroquinolones: An important class of antibiotics against tuberculosis
De Souzaa, MVN, Vasconcelos, TRA, de Almeida, MV, and Cardoso, SH
CURRENT MEDICINAL CHEMISTRY 2006. 13(4): 455-463, 9
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235298200006
36. 48600 OI-LS-343; WOS-OI-2/26/2006
Novel yeast cell-based assay to screen for inhibitors of human cytomegalovirus protease in a high-throughput format
Cottier, V, Barberis, A, and Luthi, U
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 2006. 50(2): 565-571, 7
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235294200022
37. 48601 OI-LS-343; WOS-OI-3/5/2006
Structural characterization and antimicrobial activity of 2- 5-H/methyl-1H-benzimidazol-2-yl)-4-bromo/nitro-phenol ligands and their Fe(NO3)(3) complexes
Tavman, A, Agh-Atabay, NM, Neshat, A, Gucin, F, Dulger, B, and Haciu, D
TRANSITION METAL CHEMISTRY 2006. 31(2): 194-200, 7
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235447200009
38. 48602 OI-LS-343; WOS-OI-3/5/2006
Application and utilization of chemoinformatics tools in lead generation and optimization
Fotouhi, N, Gillespie, P, Goodnow, RA, So, SS, Han, Y, and Babiss, LE
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING 2006. 9(2): 95-102, 8
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235468800004
39. 48603 OI-LS-343; WOS-OI-3/5/2006
Synthesis and biological evaluation of (E)-3-(nitrophenyl)-1-(pyrazin-2-yl)prop-2-en-1-ones
Opletalova, V, Pour, M, Kunes, J, Buchta, V, Silva, L, Kralova, K, Chlupacava, M, Meltrova, D, Peterka, M, and Poslednikova, M
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS 2006. 71(1): 44-58, 15
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235347200004
40. 48604 OI-LS-343; WOS-OI-3/5/2006
Understanding the RNA-specificity of HCV RdRp: Implications for anti-HCV drug discovery
Kim, J and Chong, YH
BULLETIN OF THE KOREAN CHEMICAL SOCIETY 2006. 27(1): 59-64, 6
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000235405700011