ONLINE DATABASE SEARCH - OI-LS-337-MEMO
1. 48243 OI-LS-337; PUBMED-OI-12/12/2005
1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (IspC) from Mycobacterium tuberculosis: towards Understanding Mycobacterial Resistance to Fosmidomycin
Dhiman, RK, Schaeffer, ML, Bailey, AM, Testa, CA, Scherman, H, and Crick, DC
J Bacteriol 2005. 187(24): 8395-402
HYPERLINK:
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16321944&dopt=abstract
2. 48244 OI-LS-337; SCIFINDER-OI-12/5/2005
Cloning and expression of isocitrate lyase, a key enzyme of the glyoxylate cycle, of Candida albicans for development of antifungal drugs
Shin, Dong-Sun, Kim, Sanghee, Yang, Hyeong-Cheol, and Oh, Ki-Bong
Journal of Microbiology and Biotechnology 2005. 15(3): 652-655
3. 48245 OI-LS-337; SCIFINDER-OI-12/5/2005
An update on antifungal targets and mechanisms of resistance in Candida albicans
Akins, Robert
Medical Mycology 2005. 43(4): 285-318
4. 48246 OI-LS-337; WOS-OI-12/1/2005
Recent advances in discovery and development of promising therapeutics against hepatitis C virus NS5B RNA-dependent RNA polymerase
Wu, JZ, Yao, NH, Walker, M, and Hong, Z
MINI-REVIEWS IN MEDICINAL CHEMISTRY 2005. 5(12): 1103-1112, 10
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233099600006
5. 48247 OI-LS-337; SCIFINDER-OI-12/5/2005
Synthesis and antimicrobial activity of phthalimido(2-aryl-3-isonicotinamido-4-oxo-1,3-thiazolidine-5-yl) ethanoates
Sharma, Ranjana, Ahmed, M, Sharma, Kanika, and Talesara, GL
Indian Journal of Pharmaceutical Sciences 2005. 67(4): 462-466
6. 48248 OI-LS-337; SCIFINDER-OI-12/5/2005
Tin(IV) complexes of pyrrolidinedithiocarbamate: synthesis, characterisation and antifungal activity
Menezes, DC, Vieira, FT, de Lima, GM, Porto, AO, Cortes, ME, Ardisson, JD, and Albrecht-Schmitt, TE
European Journal of Medicinal Chemistry 2005. 40(12): 1277-1282
7. 48249 OI-LS-337; SCIFINDER-OI-12/5/2005
Metal complexes of 2-benzoylpyridine-derived thiosemicarbazones: structural, electrochemical and biological studies
Costa, Ricardo FF, Rebolledo, Anayive P, Matencio, Tulio, Calado, Hallen DR, Ardisson, Jose D, Cortes, Maria E, Rodrigues, Bernardo L, and Beraldo, Heloisa
Journal of Coordination Chemistry 2005. 58(15): 1307-1319
8. 48250 OI-LS-337; WOS-OI-12/1/2005
Facile synthesis of active antitubercular, cytotoxic and antibacterial agents: a Michael addition approach
Chande, MS, Verma, RS, Barve, PA, Khanwelkar, RR, Vaidya, RB, and Ajaikumar, KB
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2005. 40(11): 1143-1148, 6
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233184600010
9. 48251 OI-LS-337; SCIFINDER-OI-12/5/2005
Compound IKD-8344, a selective growth inhibitor against the mycelial form of Candida albicans, isolated from Streptomyces sp. A6792
Hwang, Eui Il, Yun, Bong Sik, Yeo, Woon Hyung, Lee, Sang Han, Moon, Jae Sun, Kim, Young Kook, Lim, Se Jin, and Kim, Sung Uk
Journal of Microbiology and Biotechnology 2005. 15(4): 909-912
10. 48252 OI-LS-337; WOS-OI-12/1/2005
Organophosphorus chemistry: Therapeutic intervention in mechanisms of viral and cellular replication
Wardle, NJ, Bligh, SWA, and Hudson, HR
CURRENT ORGANIC CHEMISTRY 2005. 9(18): 1803-1828, 26
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233104300002
11. 48253 OI-LS-337; SCIFINDER-OI-12/5/2005
Pharmaceuticals and antifungal agents containing water-soluble triazoles
Uchida, Takuya, Mikojima, Yoshiko, Konoso, Toshiyuki, and Shibayama, Takahiro
PATENT: JP 2005263636 ISSUE DATE: 20050929
APPLICATION: 2004-8458 PP: 270 pp.
ASSIGNEE: (Sankyo Co., Ltd. Japan
12. 48254 OI-LS-337; WOS-OI-12/1/2005
Treatment of tuberculosis: present status and future prospects
Onyebujoh, P, Zumla, A, Ribeiro, I, Rustomjee, R, Mwaba, P, Gomes, M, and Grange, JM
BULLETIN OF THE WORLD HEALTH ORGANIZATION 2005. 83(11): 857-865, 9
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233185100015
13. 48255 OI-LS-337; SCIFINDER-OI-12/5/2005
A murine model of dual infection with cytomegalovirus and Pneumocystis carinii: Effects of virus-induced immunomodulation on disease progression
Qureshi, Mahboob H, Garvy, Beth A, Pomeroy, Claire, Inayat, Mohammed S, and Oakley, Oliver R
Virus Research 2005. 114(1-2): 35-44
14. 48256 OI-LS-337; WOS-OI-12/4/2005
Synthesis and evaluation of demethoxyviridin derivatives as potential antimicrobials
Kiran, I, Ilhan, S, Akar, T, Tur, L, and Erol, E
ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES 2005. 60(9-10): 686-692, 7
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233276000005
15. 48257 OI-LS-337; SCIFINDER-OI-12/5/2005
Mycobacterial resistance to reactive oxygen and nitrogen intermediates: Recent views and progress in M. Tuberculosis
Rhee, Kyu Y
Mycobacterium 2005.: 321-345
16. 48258 OI-LS-337; SCIFINDER-OI-12/5/2005
Update on antimicrobial agents: new indications of older agents
Pasquale, Timothy R and Tan, James S
Expert Opinion on Pharmacotherapy 2005. 6(10): 1681-1691
17. 48259 OI-LS-337; WOS-OI-12/4/2005
Antitubercular sterols from Thalia multiflora Horkel ex Koernicke
Gutierrez-Lugo, MT, Wang, YH, Franzblau, SG, Suarez, E, and Timmermann, BN
PHYTOTHERAPY RESEARCH 2005. 19(10): 876-880, 5
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233341200008
18. 48260 OI-LS-337; SCIFINDER-OI-12/5/2005
Use of GeneDecipher software for predicting protein coding sequences useful as drug targets, for development of antimicrobial agents
Brahmachari, Samir Kumar, Dash, Debasis, Sharma, Ramakant, and Maheshwari, Jitendra Kumar
PATENT: US 2005136480 ISSUE DATE: 20050623
APPLICATION: 2004-34519 PP: 210 pp., Cont.-in-part of U.S. Ser. No. 727,989.
ASSIGNEE: (India)
19. 48261 OI-LS-337; WOS-OI-12/4/2005
New fungal metabolite geranylgeranyltransferase inhibitors with antifungal activity
Singh, SB, Kelly, R, Guan, ZQ, Polishook, JD, Dombrowski, AW, Collado, J, Gonzalez, A, Pelaez, F, Register, E, Kelly, TM, Bonfiglio, C, and Williamson, JM
NATURAL PRODUCT RESEARCH 2005. 19(8): 739-747, 9
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233410700003
20. 48262 OI-LS-337; WOS-OI-12/4/2005
Detection of anti-hepatitis C virus effects of interferon and ribavirin by a sensitive replicon system
Kato, T, Date, T, Miyamoto, M, Sugiyama, M, Tanaka, Y, Orito, E, Ohno, T, Sugihara, K, Hasegawa, I, Fujiwara, K, Ito, K, Ozasa, A, Mizokami, M, and Wakita, T
JOURNAL OF CLINICAL MICROBIOLOGY 2005. 43(11): 5679-5684, 6
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233312200042
21. 48263 OI-LS-337; SCIFINDER-OI-12/5/2005
Phenyl(quinazolinyl)amines as UL 97-kinase inhibitors for the treatment of human cytomegaloviral and other herpesviral infections
Herget, Thomas
PATENT: WO 2005040125 ISSUE DATE: 20050506
APPLICATION: 2004 PP: 56 pp.
ASSIGNEE: (Axxima Pharmaceuticals A.-G., Germany
22. 48264 OI-LS-337; WOS-OI-12/4/2005
Conditional depletion of KasA, a key enzyme of mycolic acid biosynthesis, leads to mycobacterial cell lysis
Bhatt, A, Kremer, L, Dai, AZ, Sacchettini, JC, and Jacobs, WR
JOURNAL OF BACTERIOLOGY 2005. 187(22): 7596-7606, 11
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233400200007
23. 48265 OI-LS-337; WOS-OI-12/4/2005
QSAR analysis of 2,4-diaminopyrido[2,3-d]pyrimidines and 2,4-diaminopyrrolo[2,3-d]pyrimidines as dihydrofolate reductase inhibitors
Jain, P, Soni, LK, Gupta, AK, and Kashkedikar, SG
INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS 2005. 42(5): 315-320, 6
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233316300007
24. 48266 OI-LS-337; SCIFINDER-OI-12/5/2005
Preparation of imidazol-4-yl-N'-phenylureas as antiviral agents
Zimmermann, Holger, Brueckner, David, Heimbach, Dirk, Hendrix, Martin, Henninger, Kerstin, Hewlett, Guy, Rosentreter, Ulrich, Keldenich, Joerg, Lang, Dieter, and Radtke, Martin
PATENT: WO 2005092865 ISSUE DATE: 20051006
APPLICATION: 2005 PP: 124 pp.
ASSIGNEE: (Bayer Healthcare A.-G., Germany
25. 48267 OI-LS-337; SCIFINDER-OI-12/5/2005
Screening of antiviral drugs, and pharmaceutical compositions containing 2-thioxothiazolidinone derivatives
Gregor, Paul, Harris, Nicholas, and Zhuk, Regina
PATENT: WO 2005089067 ISSUE DATE: 20050929
APPLICATION: 2005 PP: 52 pp.
ASSIGNEE: (Rimonyx Pharmaceuticals Ltd., Israel
26. 48268 OI-LS-337; SCIFINDER-OI-12/5/2005
Preparation of 2'-C-methyl nucleoside derivatives and their uses for the treatment of hepatitis C viral infection
Reddy, KRaja and Erion, Mark D
PATENT: US 2005182252 ISSUE DATE: 20050818
APPLICATION: 2004-51247 PP: 84 pp.
ASSIGNEE: (USA)
27. 48269 OI-LS-337; SCIFINDER-OI-12/5/2005
Novel potent allosteric inhibitors of HCV NS5B polymerase
Brochu, Christian, Coulombe, Rene, Gillard, James R, Jolicoeur, Eric, Kohlbauer, Peter, Kuhn, Peter, Poupart, Marc-Andre, Lefebvre, Sylvain, McKercher, Ginette, Kukolj, George, and Beaulieu, Pierre L
Abstracts of Papers, 230th ACS National Meeting, Washington, DC, United States, Aug. 28-Sept. 1, 2005 2005.: MEDI-015
28. 48270 OI-LS-337; SCIFINDER-OI-12/5/2005
Preparation of (1R,2S,5S)-N-[(1S)-3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-[(2S)-2-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide as inhibitor of hepatitis C virus NS3/NS4a serine protease
Njoroge, FGeorge and Venkatraman, Srikanth
PATENT: US 20050249702 ISSUE DATE: 20051110
APPLICATION: 2005-55897 PP: 14 pp.
ASSIGNEE: (Schering Corporation, USA
29. 48271 OI-LS-337; SCIFINDER-OI-12/5/2005
Preparation of N-acyldihydropyrroles as hepatitis C virus (HCV) inhibitors
Haigh, David and Slater, Martin John
PATENT: WO 2005103045 ISSUE DATE: 20051103
APPLICATION: 2005 PP: 45 pp.
ASSIGNEE: (Glaxo Group Limited, UK
30. 48272 OI-LS-337; SCIFINDER-OI-12/5/2005
In Vitro Studies of Cross-resistance Mutations against Two Hepatitis C Virus Serine Protease Inhibitors, VX-950 and BILN 2061
Lin, Chao, Gates, Cynthia A, Rao, BGovinda, Brennan, Debra L, Fulghum, John R, Luong, Yu-Ping, Frantz, JDaniel, Lin, Kai, Ma, Sue, Wei, Yun-Yi, Perni, Robert B, and Kwong, Ann D
Journal of Biological Chemistry 2005. 280(44): 36784-36791
31. 48273 OI-LS-337; WOS-OI-12/4/2005
Demonstration of the efficacy of small molecule HCV inhibitors in the KMT mouse model of hepatitis C virus (HCV) infection
Kneteman, N
HEPATOLOGY 2005. 42(4): 532A-533A, 2
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000232480301398
32. 48274 OI-LS-337; WOS-OI-12/4/2005
Identification of a novel small molecule hepatitis C virus replication inhibitor that targets host sphingolipid biosynthesis
Sakamoto, H, Okamoto, K, Aoki, M, Kato, H, Katsume, A, Ohta, A, Tsukuda, T, Shimma, N, Aoki, Y, Arisawa, M, Kohara, M, and Sudoh, M
HEPATOLOGY 2005. 42(4): 535A-1
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000232480301404
33. 48275 OI-LS-337; SCIFINDER-OI-12/5/2005
Heterocyclic anti-viral compounds comprising metabolizable moieties and their uses as inhibitors of hepatitis C virus replication and/or proliferation for treatment of hepatitis C infection
Singh, Rajinder, Goff, Dane, Kolluri, Rao SS, Darwish, Ihab S, Partridge, John, Cooper, Robin, Lu, Henry H, and Park, Gary
PATENT: WO 2005097760 ISSUE DATE: 20051020
APPLICATION: 2005 PP: 149 pp.
ASSIGNEE: (Rigel Pharmaceuticals, Inc. USA
34. 48276 OI-LS-337; WOS-OI-12/4/2005
SCH 503034, a mechanism-based inhibitor of hepatitis C virus (HCV) NS3 protease suppresses polyprotein maturation and enhances the antiviral activity of interferona-211 (INF)
Malcolm, BA, Arassappan, A, Bennett, F, Bogen, S, Chase, R, Chen, K, Chen, T, Ingravallo, P, Jao, E, Kong, S, Lahser, F, Liu, R, Liu, YT, Lovey, R, McCormick, J, Njoroge, GF, Saksana, A, Skelton, A, Tong, X, Venkatraman, S, Wright-Minogue, J, Xia, E, and Girijavallabhan, V
HEPATOLOGY 2005. 42(4): 535A-536A, 2
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000232480301405
35. 48277 OI-LS-337; WOS-OI-12/4/2005
NIM811 exhibits potent anti-HCV activity in vitro and represents a novel approach for viral hepatitis C therapy
Lin, K, Ma, S, Boerner, J, Huang, MM, Ryder, N, Weidmann, B, and Cooreman, MP
HEPATOLOGY 2005. 42(4): 536A-1
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000232480301407
36. 48278 OI-LS-337; SCIFINDER-OI-12/5/2005
Preparation of pyrazole-4-carboxylic acids as HCV RNA polymerase inhibitors for the treatment of viral infections
Bravi, Gianpaolo, Corfield, John Andrew, Grimes, Richard Martin, Guidetti, Rossella, Lovegrove, Victoria Lucy Helen, Mordaunt, Jacqueline Elizabeth, Shah, Pritom, and Slater, Martin John
PATENT: WO 2005092863 ISSUE DATE: 20051006
APPLICATION: 2005 PP: 140 pp.
ASSIGNEE: (Glaxo Group Limited, UK
37. 48279 OI-LS-337; WOS-OI-12/4/2005
Immunophenotyping profile of CPG 10101, a new TLR9 agonist antiviral for hepatitis C
McHutchinson, JG, Bacon, BR, Gordon, SC, Lawitz, E, Shiffman, M, Afdhal, NH, Jacobson, IM, Muir, A, Efler, SM, Vicari, A, Myette, K, Ahluwalia, N, Murzenok, PP, Lipford, G, Schmalbach, TK, Krieg, AM, and Davis, HL
HEPATOLOGY 2005. 42(4): 539A-540A, 2
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000232480301414
38. 48280 OI-LS-337; SCIFINDER-OI-12/5/2005
Preparation of novel peptidyl ketoamides with cyclic p4s as inhibitors of NS3 serine protease of hepatitis C virus
Chen, Kevin X, Njoroge, FGeorge, Sannigrahi, Mousumi, Nair, Latha G, Yang, Weiying, Vibulbhan, Bancha, Venkatraman, Srikanth, Arasappan, Ashok, Bogen, Stephane L, Bennett, Frank, and Girijavallabhan, Viyyoor M
PATENT: WO 2005085242 ISSUE DATE: 20050915
APPLICATION: 2005 PP: 282 pp.
ASSIGNEE: (Schering Corporation, USA
39. 48281 OI-LS-337; WOS-OI-12/4/2005
Two flavonoids extracts from a harb, glycyrrhizae radix, inhibit in-vitro hepatitis C virus replication
Sekine, Y, Sakamoto, N, Nakagawa, M, Itsui, Y, Tasaka, M, Chen, CH, and Watanabe, M
HEPATOLOGY 2005. 42(4): 702A-1
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000232480302336
40. 48282 OI-LS-337; WOS-OI-12/4/2005
The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymerases
Ferron, F, Bussetta, C, Dutartre, H, and Canard, B
BMC BIOINFORMATICS 2005. 6: 16
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233338800001
41. 48283 OI-LS-337; WOS-OI-12/4/2005
Piperazine propanol derivative as a novel antifungal targeting 1,3-beta-D-glucan synthase
Kondoh, O, Inagaki, Y, Fukuda, H, Mizuguchi, E, Ohya, Y, Arisawa, M, Shimma, N, Aoki, Y, Sakaitani, M, and Watanabe, T
BIOLOGICAL & PHARMACEUTICAL BULLETIN 2005. 28(11): 2138-2141, 4
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233348500022
42. 48284 OI-LS-337; WOS-OI-12/4/2005
ChemDB: a public database of small molecules and related chemoinformatics resources
Chen, J, Swamidass, SJ, Bruand, J, and Baldi, P
BIOINFORMATICS 2005. 21(22): 4133-4139, 7
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233218100009
43. 48285 OI-LS-337; WOS-OI-12/4/2005
Gene expression profiling analysis of Mycobacterium tuberculosis genes in response to salicylate
Denkin, S, Byrne, S, Jie, C, and Zhang, Y
ARCHIVES OF MICROBIOLOGY 2005. 184(3): 152-157, 6
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233242900002
44. 48286 OI-LS-337; WOS-OI-12/4/2005
Proline-based macrocyclic inhibitors of the hepatitis C virus: Stereoselective synthesis and biological activity
Chen, KX, Njoroge, EG, Vibulbhan, B, Prongay, A, Pichardo, J, Madison, V, Buevich, A, and Chan, TM
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2005. 44(43): 7024-7028, 5
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233279800005
45. 48287 OI-LS-337; WOS-OI-12/11/2005
A highly efficient, asymmetric synthesis of benzothiadiazine-substituted tetramic acids: Ppotent inhibitors of hepatitis C virus RNA-dependent RNA polymerase
Fitch, DM, Evans, KA, Chai, DP, and Duffy, KJ
ORGANIC LETTERS 2005. 7(24): 5521-5524, 4
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233505700044
46. 48288 OI-LS-337; WOS-OI-12/11/2005
Tetrahydrobenzothiophene inhibitors of hepatitis C virus NS5B polymerase
LaPorte, MG, Lessen, TA, Leister, L, Cebzanov, D, Amparo, E, Faust, C, Ortlip, D, Bailey, TR, Nitz, TJ, Chunduru, SK, Young, DC, and Burns, CJ
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2006. 16(1): 100-103, 4
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000233516200020