ONLINE DATABASE SEARCH - OI-LS-295-MEMO
1. 43343 OI-LS-295; PUBMED-OI-5/3/2004
Arylamine N-Acetyltransferase Is Required for Synthesis of Mycolic Acids and Complex Lipids in Mycobacterium bovis BCG and Represents a Novel Drug Target
Bhakta, S, Besra, GS, Upton, AM, Parish, T, Sholto-Douglas-Vernon, C, Gibson, KJ, Knutton, S, Gordon, S, DaSilva, RP, Anderton, MC, and Sim, E
J Exp Med 2004
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15117974&dopt=abstract
2. 43344 OI-LS-295; PUBMED-OI-5/3/2004
Antimicrobial activity of clofazimine is not dependent on mycobacterial C-type phospholipases
Bopape, MC, Steel, HC, Cockeran, R, Matlola, NM, Fourie, PB, and Anderson, R
J Antimicrob Chemother 2004
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15117926&dopt=abstract
3. 43345 OI-LS-295; PUBMED-OI-5/3/2004
Cellular RNA Helicase p68 Relocalization and Interaction with the Hepatitis C Virus (HCV) NS5B Protein and the Potential Role of p68 in HCV RNA Replication
Goh, PY, Tan, YJ, Lim, SP, Tan, YH, Lim, SG, Fuller-Pace, F, and Hong, W
J Virol 2004. 78(10): 5288-5298
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15113910&dopt=abstract
4. 43346 OI-LS-295; SCIFINDER-OI-4/27/2004
Effect of antiretroviral protease inhibitors alone, and in combination with paromomycin, on the excystation, invasion and in vitro development of Cryptosporidium parvum
Dugue, Geoffrey A
Journal of Antimicrobial Chemotherapy 2004. 53(2): 403
5. 43347 OI-LS-295; PUBMED-OI-5/3/2004
Design, synthesis, and computational affinity prediction of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii
Graffner-Nordberg, M, Kolmodin, K, Aqvist, J, Queener, SF, and Hallberg, A
Eur J Pharm Sci 2004. 22(1): 43-54
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15113582&dopt=abstract
6. 43348 OI-LS-295; PUBMED-OI-5/3/2004
Natural antimycobacterial metabolites: current status
Okunade, AL, Elvin-Lewis, MP, and Lewis, WH
Phytochemistry 2004. 65(8): 1017-32
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15110681&dopt=abstract
7. 43349 OI-LS-295; PUBMED-OI-5/3/2004
Activities of benzimidazole d- and L-ribonucleosides in animal models of cytomegalovirus infections
Kern, ER, Hartline, CB, Rybak, RJ, Drach, JC, Townsend, LB, Biron, KK, and Bidanset, DJ
Antimicrob Agents Chemother 2004. 48(5): 1749-55
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15105130&dopt=abstract
8. 43350 OI-LS-295; PUBMED-OI-5/3/2004
Mechanism of Action of the Ribopyranoside Benzimidazole GW275175X against Human Cytomegalovirus
Underwood, MR, Ferris, RG, Selleseth, DW, Davis, MG, Drach, JC, Townsend, LB, Biron, KK, and Boyd, FL
Antimicrob Agents Chemother 2004. 48(5): 1647-1651
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15105116&dopt=abstract
9. 43351 OI-LS-295; PUBMED-OI-5/3/2004
In Vitro Antifungal Activities of Inhibitors of Phospholipases from the Fungal Pathogen Cryptococcus neoformans
Ganendren, R, Widmer, F, Singhal, V, Wilson, C, Sorrell, T, and Wright, L
Antimicrob Agents Chemother 2004. 48(5): 1561-9
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15105106&dopt=abstract
10. 43352 OI-LS-295; PUBMED-OI-5/3/2004
Mycobacterium tuberculosis Growth Inhibition by Constituents of Sapiumhaematospermum
Woldemichael, GM, Gutierrez-Lugo, MT, Franzblau, SG, Wang, Y, Suarez, E, and Timmermann, BN
J Nat Prod 2004. 67(4): 598-603
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15104489&dopt=abstract
11. 43353 OI-LS-295; SCIFINDER-OI-4/27/2004
Comparative genomics of Pneumocystis carinii with other protists: implications for life style
Cushion, Melanie T
Journal of Eukaryotic Microbiology 2004. 51(1): 30-37
12. 43354 OI-LS-295; PUBMED-OI-5/3/2004
Mycobacterium tuberculosis RmlC epimerase (Rv3465): a promising drug-target structure in the rhamnose pathway
Kantardjieff, KA, Kim, CY, Naranjo, C, Waldo, GS, Lekin, T, Segelke, BW, Zemla, A, Park, MS, Terwilliger, TC, and Rupp, B
Acta Crystallogr D Biol Crystallogr 2004. 60(Pt 5): 895-902
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15103135&dopt=abstract
13. 43355 OI-LS-295; SCIFINDER-OI-4/27/2004
Flucytosine resistance is restricted to a single genetic clade of Candida albicans
Pujol, Claude, Pfaller, Michael A, and Soll, David R
Antimicrobial Agents and Chemotherapy 2004. 48(1): 262-266
14. 43356 OI-LS-295; SCIFINDER-OI-4/27/2004
Synthesis, structure and anti-fungal activity of dimeric Ag(I) complexes containing bis-imidazole ligands
Abuskhuna, Suaad, Briody, John, McCann, Malachy, Devereux, Michael, Kavanagh, Kevin, Fontecha, Julia Barreira, and McKee, Vickie
Polyhedron 2004. 23(7): 1249-1255
15. 43357 OI-LS-295; SCIFINDER-OI-4/27/2004
Isoxazole derivative inhibitors of fungal invasion, and preparation thereof((Microbia, Inc. USA)
Talley, John Jeffrey, Fretzen, Angelika, Zimmerman, Craig, Barden, Timothy, Yang, Jing Jing, Martinez, Eduardo, Busby, Robert, Cordero, Etchell A, Houman, Fariba, Pierce, Christine M, and Summers, Eric F
PATENT: WO 2004021997 A2; ISSUE DATE: 20040318
APPLICATION: 2003; PP: 114 pp.
16. 43358 OI-LS-295; PUBMED-OI-5/3/2004
In vitro synergic antifungal effect of MUC7 12-mer with histatin-5 12-mer or miconazole
Wei, GX and Bobek, LA
J Antimicrob Chemother 2004. 53(5): 750-8
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15073161&dopt=abstract
17. 43359 OI-LS-295; PUBMED-OI-5/3/2004
Global spotlight falls on tuberculosis
Das, P
Lancet Infect Dis 2004. 4(4): 188
HYPERLINK: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15072057&dopt=abstract
18. 43360 OI-LS-295; WOS-OI-4/25/2004
The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation
Choi, KH, Groarke, JM, Young, DC, Kuhn, RJ, Smith, JL, Pevear, DC, and Rossmann, MG
P NATL ACAD SCI USA 2004. 101(13): 4425-4430
HYPERLINK: http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220648700020
19. 43361 OI-LS-295; SCIFINDER-OI-4/27/2004
Antifungal antibiotic polycyclic compound from marine sponge((Yamanouchi Pharmaceutical Co., Ltd. Japan)
Shibazaki, Mitsuharu, Watanabe, Masato, Fusetani, Nobuhiro, Matsunaga, Shigeki, and Nishimura, Shinichi
PATENT: JP 2004059542 A2; ISSUE DATE: 20040226
APPLICATION: 2002-26811; PP: 8 pp.
20. 43362 OI-LS-295; WOS-OI-4/25/2004
Chemogenomics: An emerging strategy for rapid target and drug discovery
Bredel, M and Jacoby, E
NAT REV GENET 2004. 5(4): 262-275
HYPERLINK: http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220559200012
21. 43363 OI-LS-295; WOS-OI-4/25/2004
Usefulness of graphical invariants in quantitative structure-activity correlations of tuberculostatic drugs of the isonicotinic acid hydrazide type
Bagchi, MC, Maiti, BC, Mills, D, and Basak, SC
J MOL MODEL 2004. 10(2): 102-111
HYPERLINK: http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220564500003
22. 43364 OI-LS-295; SCIFINDER-OI-4/27/2004
2,4-diaminoquinazoline and pyridopyrimidine ester derivatives as dihydrofolate reductase inhibitors((Melacure Therapeutics Ab, Swed. and Pett, Christopher Phineas)
Hallberg, Anders, Graffner-nordberg, Malin, Boman, Arne, and Seifert, Elisabeth
PATENT: WO 2004020418 A1; ISSUE DATE: 20040311
APPLICATION: 2003; PP: 41 pp.
23. 43365 OI-LS-295; SCIFINDER-OI-4/27/2004
Mycobacterium tuberculosis cell envelope lipids and the host immune response
Karakousis, Petros C, Bishai, William R, and Dorman, Susan E
Cellular Microbiology 2004. 6(2): 105-116
24. 43366 OI-LS-295; SCIFINDER-OI-4/27/2004
Antibacterial inhibitors of Ftsz protein ((Southern Research Institute, USA)
White, Lucile E, Reynolds, Robert C, and Suling, William
PATENT: WO 2004005472 A2; ISSUE DATE: 20040115
APPLICATION: 2003; PP: 117 pp.
25. 43367 OI-LS-295; WOS-OI-4/25/2004
Synthesis of 3,5-disubstituted isoxazolines as potential antibacterial and antifungal agents
Imran, M and Khan, SA
INDIAN J HETEROCY CH 2004. 13(3): 213-216
HYPERLINK: http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220614800007
26. 43368 OI-LS-295; WOS-OI-4/25/2004
Synthesis and biological evaluation of some cyanopyridines and isoxazoles
Hirpara, K, Patel, S, Joshi, A, and Parekh, H
INDIAN J HETEROCY CH 2004. 13(3): 221-224
HYPERLINK: http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220614800009
27. 43369 OI-LS-295; SCIFINDER-OI-4/27/2004
Preparation of phenyl oxazolidinone derivatives as antimycobacterial agents((Lupin Limited, India)
Arora, Sudershan Kumar, Patil, Vijaykumar Jagdishwar, Nair, Prathap Sreedharan, Dixit, Prasad Purushottam, Ajay, Shankar, and Sinha, Rakesh Kumar
PATENT: WO 2004026848 A1; ISSUE DATE: 20040401
APPLICATION: 2002; PP: 84 pp.
28. 43370 OI-LS-295; SCIFINDER-OI-4/27/2004
Early bactericidal activity of moxifloxacin in treatment of pulmonary tuberculosis: a prospective, randomized study
Pletz, Mathias WR, De Roux, Andres, Roth, Andreas, Neumann, Karl-Heinz, Mauch, Harald, and Lode, Hartmut
Antimicrobial Agents and Chemotherapy 2004. 48(3): 780-782
29. 43371 OI-LS-295; SCIFINDER-OI-4/27/2004
Immunization with a DNA vaccine cocktail protects mice lacking CD4 cells against an aerogenic infection with Mycobacterium tuberculosis
Derrick, Steven C, Repique, Charlene, Snoy, Philip, Yang, Amy Li, and Morris, Sheldon
Infection and Immunity 2004. 72(3): 1685-1692
30. 43372 OI-LS-295; SCIFINDER-OI-4/27/2004
Preparation of heteroarylethanolamines as antiviral agents((Pharmacia & Upjohn Company, USA and Fleck, Bruce Francis)
Fleck, Thomas J, Schnute, Mark E, Cudahy, Michele M, Anderson, David J, Judge, Thomas M, Herrington, Paul M, Nair, Sajiv K, Scott, Allen, Perrault, William R, Tanis, Steven P, Nieman, James A, and Collier, Sarah A
PATENT: WO 2004022567 A1; ISSUE DATE: 20040318
APPLICATION: 2003; PP: 90 pp.
31. 43373 OI-LS-295; SCIFINDER-OI-4/27/2004
Preparation of 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents((Pharmacia & Upjohn Company, USA)
Schnute, Mark E, Ciske, Fred L, Genin, Michael J, Strohbach, Joseph W, and Thaisrivongs, Suvit
PATENT: WO 2004022566 A1; ISSUE DATE: 20040318
APPLICATION: 2003; PP: 74 pp.
32. 43374 OI-LS-295; SCIFINDER-OI-4/27/2004
Use of triptans as antiviral agents ((Italy))
Cassar Scalia, Antonio
PATENT: WO 2004019934 A1; ISSUE DATE: 20040311
APPLICATION: 2003; PP: 10 pp.
33. 43375 OI-LS-295; SCIFINDER-OI-4/27/2004
1-Deaza-5'-noraisteromycin
Yin, Xueqiang and Schneller, Stewart W
Nucleosides, Nucleotides & Nucleic Acids 2004. 23(1 & 2): 67-76
34. 43376 OI-LS-295; WOS-OI-5/2/2004
The human immune response to Mycobacterium tuberculosis in lung and lymph node
Marino, S and Kirschner, DE
J THEOR BIOL 2004. 227(4): 463-486
HYPERLINK: http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220674100002
35. 43377 OI-LS-295; WOS-OI-5/2/2004
Design and syntheses of 1,6-naphthalene derivatives as selective HCMV protease inhibitors
Gopalsamy, A, Lim, K, Ellingboe, JW, Mitsner, B, Nikitenko, A, Upeslacis, J, Mansour, TS, Olson, MW, Bebernitz, GA, Grinberg, D, Feld, B, Moy, FJ, and O'Connell, J
J MED CHEM 2004. 47(8): 1893-1899
HYPERLINK: http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220642100006
36. 43378 OI-LS-295; WOS-OI-5/2/2004
Distamycin analogues with enhanced lipophilicity: Synthesis and antimicrobial activity
Khalaf, AI, Waigh, RD, Drummond, AJ, Pringle, B, McGroarty, I, Skellern, GG, and Suckling, CJ
J MED CHEM 2004. 47(8): 2133-2156
HYPERLINK: http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220642100026
37. 43379 OI-LS-295; WOS-OI-5/2/2004
Antimicrobial dihydrofolate reductase inhibitors achievements and future options: Review
Then, RL
J CHEMOTHERAPY 2004. 16(1): 3-12
HYPERLINK: http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220644000001
38. 43380 OI-LS-295; SCIFINDER-OI-4/27/2004
Antiviral action of ribavirin in chronic hepatitis C
Pawlotsky, Jean-Michel, Dahari, Harel, Neumann, Avidan U, Hezode, Christophe, Germanidis, Georgios, Lonjon, Isabelle, Castera, Laurent, and Dhumeaux, Daniel
Gastroenterology 2004. 126(3): 703-714