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2. Development of Human Immunodeficiency Virus Type 1 Resistance to 4'-Ethynyl-2-fluoro-2'-deoxyadenosine Starting with Wild-Type or Nucleoside Reverse Transcriptase Inhibitor-resistant Strains. Cilento, M.E., A.B. Reeve, E. Michailidis, T.V. Ilina, E. Nagy, H. Mitsuya, M.A. Parniak, P.R. Tedbury, and S.G. Sarafianos. Antimicrobial Agents and Chemotherapy, 2021. 65(12): e0116721. PMID[34516245]. PMCID[PMC8597736].
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3. Development of Triazoles and Triazolium Salts Based on AZT and Their Anti-viral Activity against HIV-1. de Alencar, D.M., J. Gonçalves, A. Vieira, S.A. Cerqueira, C. Sebastião, M. Leitão, G. Francescato, P. Antenori, H. Soares, and A. Petronilho. Molecules, 2021. 26(21): 6720. PMID[34771129]. PMCID[PMC8588071].
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4. Flavonoids and Acid-hydrolysis Derivatives of Neo-Clerodane Diterpenes from Teucrium flavum Subsp. Glaucum as Inhibitors of the HIV-1 Reverse Transcriptase-associated RNase H Function. Fois, B., A. Corona, E. Tramontano, S. Distinto, E. Maccioni, R. Meleddu, P. Caboni, C. Floris, and F. Cottiglia. Journal of Enzyme Inhibition and Medicinal Chemistry, 2021. 36(1): p. 749-757. PMID[33715562]. PMCID[PMC7952052].
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5. Identification of gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-molecule CD4-Mimics. Fritschi, C.J., S. Liang, M. Mohammadi, S. Anang, F. Moraca, J. Chen, N. Madani, J.G. Sodroski, C.F. Abrams, W.A. Hendrickson, and A.B. Smith, 3rd. ACS Medicinal Chemistry Letters, 2021. 12(11): p. 1824-1831. PMID[34795873]. PMCID[PMC8591726].
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6. Rational Screening for Inhibitors of the HIV Integrase-Ku70 (XRCC6) Interaction. Ilgova, E., S. Galkin, A. Anisenko, and M. Gottikh. Protein Science, 2021. 30: p. 58-59. ISI[000711562500104].
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7. Natural Occurring Polymorphisms in HIV-1 Integrase and RNase H Regulate Viral Release and Autoprocessing. Imamichi, T., J.G. Bernbaum, S. Laverdure, J. Yang, Q. Chen, H. Highbarger, M. Hao, H. Sui, R. Dewar, W. Chang, and H.C. Lane. Journal of Virology, 2021. 95(23): e0132321. PMID[34523971]. PMCID[PMC8577372].
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8. Design, Synthesis, Docking Study and Biological Evaluation of 4-Hydroxy-2H-benzo[e]1,2 thiazine-3-carboxamide 1,1-dioxide Derivatives as anti-HIV Agents. Imani, A., S. Soleymani, R. Vahabpour, Z. Hajimahdi, and A. Zarghi. Iranian Journal of Pharmaceutical Research, 2021. 20(3): p. 1-12. ISI[000714005300001].
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9. Pharmacologic Control of Homeostatic and Antigen-driven Proliferation to Target HIV-1 Persistence. Innis, E.A., C. Levinger, M.A. Szaniawski, E. Williams, J. Alcamí, A. Bosque, J.T. Schiffer, M. Coiras, A.M. Spivak, and V. Planelles. Biochemical Pharmacology, 2021. 194: 114816. PMID[34715067]. PMCID[PMC8629953].
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10. Design of gp120 HIV-1 Entry Inhibitors by Scaffold Hopping Via Isosteric Replacements. Iusupov, I.R., F. Curreli, E.A. Spiridonov, P.O. Markov, S. Ahmed, D.S. Belov, E.V. Manasova, A. Altieri, A.V. Kurkin, and A.K. Debnath. European Journal of Medicinal Chemistry, 2021. 224: 113681. PMID[34246921]. PMCID[PMC8511295].
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11. Discovery of Modified Amidate (ProTide) Prodrugs of Tenofovir with Enhanced Antiviral Properties. Kalčic, F., M. Zgarbová, J. Hodek, K. Chalupský, M. Dračínský, A. Dvořáková, T. Strmeň, J. Šebestík, O. Baszczyňski, J. Weber, H. Mertlíková-Kaiserová, and Z. Janeba. Journal of Medicinal Chemistry, 2021. 64(22): p. 16425-16449. PMID[34713696].
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12. Neochlorogenic acid: An anti-HIV Active Compound Identified by Screening of Cortex Mori [Morus alba L. (Moraceae)]. Li, J., L. Dou, S. Chen, H. Zhou, and F. Mou. Pharmaceutical Biology, 2021. 59(1): p. 1517-1527. PMID[34714196]. PMCID[PMC8567877].
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13. HIV-1 gp120 Antagonists Also Inhibit HIV-1 Reverse Transcriptase by Bridging the NNRTI and NRTI Sites. Losada, N., F.X. Ruiz, F. Curreli, K. Gruber, A. Pilch, K. Das, A.K. Debnath, and E. Arnold. Journal of Medicinal Chemistry, 2021. 64(22): p. 16530-16540. PMID[34735153].
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14. An Alternative Approach Towards C-12 Functionalized Scalaranic Sesterterpenoids Synthesis of 17-oxo-20-Norscalaran-12α,19-O-lactone. Morarescu, O., M. Grinco, V. Kulciţki, S. Shova, and N. Ungur. Marine Drugs, 2021. 19(11): 636. PMID[34822507]. PMCID[PMC8625711].
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15. Selective BCL-X(L) Antagonists Eliminate Infected Cells from a Primary-cell Model of HIV Latency but Not from ex Vivo Reservoirs. Ren, Y., S.H. Huang, A.B. Macedo, A.R. Ward, W.D.C. Alberto, T. Klevorn, L. Leyre, D.C. Copertino, T.M. Mota, D. Chan, R. Truong, T. Rohwetter, P. Zumbo, F. Dündar, D. Betel, C. Kovacs, E. Benko, A. Bosque, and R.B. Jones. Journal of Virology, 2021. 95(15): e0242520. PMID[33980597]. PMCID[PMC8274617].
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16. Probing GFP Chromophore Analogs as anti-HIV Agents Targeting LTR-III G-Quadruplex. Ryazantsev, D.Y., M.Y. Myshkin, V.A. Alferova, V.B. Tsvetkov, E.Y. Shustova, P.N. Kamzeeva, P.V. Kovalets, E.R. Zaitseva, N.S. Baleeva, T.S. Zatsepin, Z.O. Shenkarev, M.S. Baranov, L.I. Kozlovskaya, and A.V. Aralov. Biomolecules, 2021. 11(10): 1409. PMID[34680042]. PMCID[PMC8533149].
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17. In Vitro Susceptibility of HIV-1 CRF02_AG to Temsavir, the Active Compound of the Attachment Inhibitor Fostemsavir. Saladini, F., A. Giannini, F. Giammarino, A. Boccuto, F. Dragoni, I. Vicenti, and M. Zazzi. Journal of Antimicrobial Chemotherapy, 2021. 76(12): p. 3310-3312. PMID[34402509].
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19. Multiplexed Simian Immunodeficiency Virus-specific Paired RNA-guided Cas9 Nickases Inactivate Proviral DNA. Smith, L.M., J.T. Ladner, V.L. Hodara, L.M. Parodi, R.A. Harris, J.E. Callery, Z. Lai, Y. Zou, M. Raveedran, J. Rogers, and L.D. Giavedoni. Journal of Virology, 2021. 95(23): e0088221. PMID[34549979]. PMCID[PMC8577357].
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