1. Synthesis and Antiviral Evaluation of Carbocyclic Nucleoside Analogs of Nucleoside Reverse Transcriptase Translocation Inhibitor MK-8591 (4'-Ethynyl-2-fluoro-2'-deoxyadenosine). Alexandre, F.R., R. Rahali, H. Rahali, S. Guilion, T. Convard, K. Fillgroye, M.T. Lai, J.C. Meillon, M. Xu, J. Small, C.B. Dousson, and I.T. Raheem. Journal of Medicinal Chemistry, 2018. 61(20): p. 9218-9228. PMID[30265808].
[PubMed]. HIV_11_2018.
2. Hydrophilic and Amphiphilic Water-soluble Dendrimer Prodrugs Suitable for Parenteral Administration of a Non-soluble Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitor Thiocarbamate Derivative. Alfei, S., S. Catena, M. Ponassi, C. Rosano, V. Zoppi, and A. Spallarossa. European Journal of Pharmaceutical Sciences, 2018. 124: p. 153-164. PMID[30170211].
[PubMed]. HIV_11_2018.
3. Sulfono-gamma-AA Modified Peptides That Inhibit HIV-1 Fusion. Bolarinwa, O., M. Zhang, E. Mulry, M. Lu, and J.F. Cai. Organic & Biomolecular Chemistry, 2018. 16(42): p. 7878-7882. PMID[30306175]. PMCID[PMC6209519].
[PubMed]. HIV_11_2018.
4. Microwave-assisted Expeditious Synthesis of 2-Alkyl-2-(N-arylsulfonylindol-3-yl)-3-N-acyl-5-aryl-1,3,4-oxadiazolines Catalyzed by HgCl2 under Solvent-free Conditions as Potential anti-HIV-1 Agents. Che, Z., Y. Tian, S. Liu, J. Jiang, M. Hu, and G. Chen. Molecules, 2018. 23(11): e2936. PMID[30423803].
[PubMed]. HIV_11_2018.
5. Synthesis, Antiviral Activity, and Structure-Activity Relationship of 1,3-Benzodioxolyl Pyrrole-based Entry Inhibitors Targeting the Phe43 Cavity in HIV-1 gp120. Curreli, F., D.S. Belov, S. Ahmed, R.R. Ramesh, A.V. Kurkin, A. Altieri, and A.K. Debnath. ChemMedChem, 2018. 13(21): p. 2332-2348. PMID[30257071].
[PubMed]. HIV_11_2018.
6. Discovery of a Branched Peptide That Recognizes the Rev Response Element (RRE) RNA and Blocks HIV-1 Replication. Dai, Y.M., J.E. Wynn, A.N. Peralta, C. Sherpa, B. Jayaraman, H. Li, A. Verma, A.D. Frankel, S.F. Le Grice, and W.L. Santos. Journal of Medicinal Chemistry, 2018. 61(21): p. 9611-9620. PMID[30289179].
[PubMed]. HIV_11_2018.
7. A New Class of HIV-1 Inhibitors and the Target Identification via Proteomic Profiling. Ge, Y.Z., B. Zhou, R.X. Xiao, X.J. Yuan, H. Zhou, Y.C. Xu, M.A. Wainberg, Y.S. Han, and J.M. Yue. Science China Chemistry, 2018. 61(11): p. 1430-1439. ISI[000450158400015].
[WOS]. HIV_11_2018.
8. Design and Synthesis of Potent HIV-1 Protease Inhibitors Containing Bicyclic Oxazolidinone Scaffold as the P2 Ligands: Structure-Activity Studies and Biological and X-Ray Structural Studies. Ghosh, A.K., J.N. Williams, R.Y. Ho, H.M. Simpson, S. Hattori, H. Hayashi, J. Agniswamy, Y.F. Wang, I.T. Weber, and H. Mitsuya. Journal of Medicinal Chemistry, 2018. 61(21): p. 9722-9737. PMID[30354121].
[PubMed]. HIV_11_2018.
9. Identification of a Novel Broadly HIV-1-neutralizing Antibody from a CRF01_AE-infected Chinese Donor. Ju, B., D. Li, L. Ren, J. Hou, Y. Hao, H. Liang, S. Wang, J. Zhu, M. Wei, and Y. Shao. Emerging Microbes & Infections, 2018. 7(1): p. 174. PMID[30382080]. PMCID[PMC6210191].
[PubMed]. HIV_11_2018.
10. Flexibility of Small Molecular CD4 Mimics as HIV Entry Inhibitors. Kobayakawa, T., N. Ohashi, Y. Hirota, K. Takahashi, Y. Yamada, T. Narumi, K. Yoshimura, S. Matsushita, S. Harada, and H. Tamamura. Bioorganic & Medicinal Chemistry, 2018. 26(21): p. 5664-5671. PMID[30366786].
[PubMed]. HIV_11_2018.
11. From Cycloheptathiophene-3-carboxamide to Oxazinone-based Derivatives as Allosteric HIV-1 Ribonuclease H Inhibitors. Massari, S., A. Corona, S. Distinto, J. Desantis, A. Caredda, S. Sabatini, G. Manfroni, T. Felicetti, V. Cecchetti, C. Pannecouque, E. Maccioni, E. Tramontano, and O. Tabarrini. Journal of Enzyme Inhibition and Medicinal Chemistry, 2019. 34(1): p. 55-74. PMID[30362381]. PMCID[PMC6211256].
[PubMed]. HIV_11_2018.
12. A Small-molecule Inhibitor of HIV-1 Rev Function Detected by a Diversity Screen Based on RRE-Rev Interference. Prado, S., M. Beltran, A. Moreno, L.M. Bedoya, J. Alcami, and J. Gallego. Biochemical Pharmacology, 2018. 156: p. 68-77. PMID[30071201].
[PubMed]. HIV_11_2018.
13. Synthesis of New Chiral 1,3,4-Thiadiazole-based Di- and Tri-arylsulfonamide Residues and Evaluation of in Vitro anti-HIV Activity and Cytotoxicity. Shafique, M., S. Hameed, M.M. Naseer, and N.A. Al-Masoudi. Molecular Diversity, 2018. 22(4): p. 957-968. PMID[29968121].
[PubMed]. HIV_11_2018.
14. A Novel Multivalent DNA Helix-based Inhibitor Showed Enhanced anti-HIV-1 Fusion Activity. Tang, Y.J., Z.Y. Han, H.Q. Ren, J.M. Guo, H.H. Chong, Y.L. Tian, K.L. Liu, and L. Xu. European Journal of Pharmaceutical Sciences, 2018. 125: p. 244-253. PMID[30292749].
[PubMed]. HIV_11_2018.
15. Synthesis and Antiviral Activity of Water-soluble Polycarboxylic Derivatives of [60]Fullerene Loaded with 3,4-Dichlorophenyl Units. Voronov, II, V.M. Martynenko, A.V. Chernyak, J. Balzarini, D. Schols, and P.A. Troshin. Chemistry & Biodiversity, 2018. 15(11): e1800293. PMID[30168652].
[PubMed]. HIV_11_2018.
16. Evaluation of Susceptibility of HIV-1 CRF01_AE Variants to Neutralization by a Panel of Broadly Neutralizing Antibodies. Wang, H.Y., T. Yuan, T.T. Li, Y.P. Li, F. Qian, C.W. Zhu, S.J. Liang, D. Hoffmann, U. Dittmer, B.L. Sun, and R.G. Yang. Archives of Virology, 2018. 163(12): p. 3303-3315. PMID[30196320].
[PubMed]. HIV_11_2018.
17. Subpicomolar Inhibition of HIV-1 Protease with a Boronic acid. Windsor, I.W., M.J. Palte, J.C. Lukesh, B. Gold, K.T. Forest, and R.T. Raines. Journal of the American Chemical Society, 2018. 140(43): p. 14015-14018. PMID[30346745]. PMCID[PMC6249028].
[PubMed]. HIV_11_2018.
18. Investigation of the Inhibition Effect of Arachidonic acid on the Core Structure of the HIV-1 gp41. Xu, X., L. Li, Z. Liu, X. Yao, X. Zhang, S. Liu, and L. Liu. Journal of Pharmaceutical and Biomedical Analysis, 2018. 161: p. 377-382. PMID[30199809].
[PubMed]. HIV_11_2018.
19. Virtual Screening, Biological Evaluation, and 3D-QSAR Studies of New HIV-1 Entry Inhibitors That Function via the CD4 Primary Receptor. Zhang, C., H. Zhang, L.S. Huang, S. Zhu, Y. Xu, X.Q. Zhang, R.T. Schooley, X. Yang, Z. Huang, and J. An. Molecules, 2018. 23(11): e3036. PMID[30463393].
[PubMed]. HIV_11_2018.
Patent Citations
20. Preparation of Dihydrooxadiazines Having Antiinfective, Antitumoral and Antifungal Activity. Hernandez Cabanillas, A., S. Maderuelo Corral, M. Ortega Domenech, D.F. Rosero Valencia, A. Rumbero Sanchez, and V. Tena Perez. Patent. 2018. 2018-EP60518 2018197523: 57pp ; Chemical Indexing Equivalent to 169:471534 (EP).
[Patent]. HIV_11_2018.
21. FC-Fusion Protein Derivatives with High Dual HIV Antiviral and Immunomodulatory Activity. Molina, J.C., B.C. Sala, and J.M.B. Arbues. Patent. 2018. 2018-IB602 2018207023: 87pp.
[Patent]. HIV_11_2018.
22. Application of NF546 in the Preparation of Multi Effect Microbicides. Tan, S., H. Cheng, Z. Li, and S. Liu. Patent. 2018. 2018-10510659 108553472: 13pp.
[Patent]. HIV_11_2018.
23. Application of NF023 in Preparing Multi-effect Microbicide and HIV Sexual Transmission Blocker.Tan, S., Z. Li, H. Cheng, and S. Liu. Patent. 2018. 2018-10510352 108685888: 13pp.
[Patent]. HIV_11_2018.
24. Synthesis of Novel spiro-Lactam Compounds for Pharmaceutical Use. Vasconcelos Dias de Pinho e Melo, T.M., B.C. Suzano Santos, I. Bartolo, R.M. Prudencio Pignatelli, and N.E. Moura dos Santos da Costa Taveira. Patent. 2018. 2018-IB53357 2018207165: 46pp.
[Patent]. HIV_11_2018.