HIV Citation List: April 15 - April 28, 2009

Pubmed citations:

1. Identification by high throughput screening of small compounds inhibiting the nucleic acid destabilization activity of the HIV-1 nucleocapsid protein. Shvadchak V, Sanglier S, Rocle S, Villa P, Haiech J, Hibert M, Van Dorsselaer A, Mély Y, de Rocquigny H. Biochimie. 2009 Apr 25. [Epub ahead of print] PMID: 19401213

2. Anti-AIDS Agents. 78. (dagger) Design, Synthesis, Metabolic Stability Assessment, and Antiviral Evaluation of Novel Betulinic Acid Derivatives as Potent Anti-Human Immunodeficiency Virus (HIV) Agents. Qian K, Yu D, Chen CH, Huang L, Morris-Natschke SL, Nitz TJ, Salzwedel K, Reddick M, Allaway GP, Lee KH. J Med Chem. 2009 Apr 23. [Epub ahead of print] PMID: 19388685

3. The lupane-type triterpene 30-oxo-calenduladiol is a CCR5 antagonist with anti-HIV-1 and anti-chemotactic activities. Barroso-Gonzalez J, El Jaber-Vazdekis N, Garcia-Exposito L, Machado JD, Zarate R, Ravelo AG, Estevez-Braun A, Valenzuela-Fernandez A. J Biol Chem. 2009 Apr 22. [Epub ahead of print] PMID: 19386595

4. Synthesis and Antiviral Activity of 7-Benzyl-4-hydroxy-1,5-naphthyridin-2(1H)-one HIV Integrase Inhibitors. Boros EE, Edwards CE, Foster SA, Fuji M, Fujiwara T, Garvey EP, Golden PL, Hazen RJ, Jeffrey JL, Johns BA, Kawasuji T, Kiyama R, Koble CS, Kurose N, Miller WH, Mote AL, Murai H, Sato A, Thompson JB, Woodward MC, Yoshinaga T. J Med Chem. 2009 Apr 17. [Epub ahead of print] PMID: 19374386

5. Comparative study of the persistence of anti-HIV activity of deoxynucleoside HIV reverse transcriptase inhibitors after removal from culture. Paintsil E, Grill SP, Dutschman GE, Cheng YC. AIDS Res Ther. 2009 Apr 22;6(1):5. [Epub ahead of print] PMID: 19386130

6. Study on the Inhibitory Mechanism and Binding Mode of the Hydroxycoumarin Compound NSC158393 to HIV-1 Integrase by Molecular Modeling. Liu M, Cong XJ, Li P, Tan JJ, Chan WZ, Wang CX. Biopolymers. 2009 Apr 20. [Epub ahead of print] PMID: 19382173

7. In Silico Drug Screening Approach for the Design of Magic Bullets: A Successful Example with Anti-HIV Fullerene Derivatized Amino Acids. Durdagi S, Supuran CT, Strom TA, Doostdar N, Kumar MK, Barron AR, Mavromoustakos T, Papadopoulos MG. J Chem Inf Model. 2009 Apr 16. [Epub ahead of print] PMID: 19371030

8. Synthesis of dammarane-type triterpene derivatives and their ability to inhibit HIV and HCV proteases. Wei Y, Ma CM, Hattori M. Bioorg Med Chem. 2009 Apr 15;17(8):3003-10. Epub 2009 Mar 14. PMID: 19339186

9. Discovery of dual inhibitors targeting both HIV-1 capsid and human cyclophilin A to inhibit the assembly and uncoating of the viral capsid. Li J, Tan Z, Tang S, Hewlett I, Pang R, He M, He S, Tian B, Chen K, Yang M. Bioorg Med Chem. 2009 Apr 15;17(8):3177-88. Epub 2009 Mar 3. PMID: 19328002

10. Synthesis and antiviral activities of novel acylhydrazone derivatives targeting HIV-1 capsid protein. Tian B, He M, Tang S, Hewlett I, Tan Z, Li J, Jin Y, Yang M. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2162-7. Epub 2009 Mar 4. PMID: 19297155

Patent citations:

11. Compounds with HIV-1 integrase inhibitory activity and use thereof as anti-HIV/AIDS therapeutics. Neamati, Nouri; Dayam, Raveendra S. (University of Southern California, USA). U.S. Pat. Appl. Publ. (2009), 109pp. CODEN: USXXCO US 2009088420 A1 20090402 Patent written in English. Application: US 2008-102619 20080414. Priority: US 2007-911446 20070412. AN 2009:395326 CAPLUS

12. Preparation of piperidinyl 3,9-diazaspiro[5.5]undecanes as antiviral agents. Gabriel, Stephen Deems; Lin, Xiao-Fa; Makra, Ferenc; Rotstein, David Mark; Yang, Hanbiao. (F. Hoffmann-La Roche AG, Switz.). PCT Int. Appl. (2009), 62pp. CODEN: PIXXD2 WO 2009037168. Application: WO 2008-EP62013 20080911. Priority: US 2007-994426 20070919; US 2008-84724 20080730. CAN 150:352121 AN 2009:364113 CAPLUS

13. Flexible, polyvalent antiviral dendritic conjugates for the treatment of HIV/AIDS and enveloped viral infection. Subramaniam, Sriram; Bennett, Adam. (Government of the United States of America, As Represented by the Secretary, Department of Health and Human Services, USA). PCT Int. Appl. (2009), 49pp. CODEN: PIXXD2 WO 2009038605 A2 20090326 Application: WO 2008-US6922 20080531. Priority: US 2007-932464 20070531. CAN 150:382960 AN 2009:360028 CAPLUS

14. Studies on anti-HIV quinolones: New insights on the C-6 position. Massari, Serena; Daelemans, Dirk; Manfroni, Giuseppe; Sabatini, Stefano; Tabarrini, Oriana; Pannecouque, Christophe; Cecchetti, Violetta. Dipartimento di Chimica e Tecnologia del Farmaco, Universita degli studi di Perugia, Perugia, Italy. Bioorganic & Medicinal Chemistry (2009), 17(2), 667-674. Publisher: Elsevier B.V., CODEN: BMECEP ISSN: 0968-0896. Journal written in English. CAN 150:344134 AN 2009:113896 CAPLUS

ISI Web of Science citations:

15. Amide-containing diketoacids as HIV-1 integrase inhibitors: Synthesis, structure-activity relationship analysis, and biological activity. Li HC, Wang C, Sanchez T, Tan YM, Jiang CY, Neamati N, Zhao GS.BIOORGANIC & MEDICINAL CHEMISTRY, 2009; 17(7): 2913-2919.

16. Synthesis and antiviral activities of novel acylhydrazone derivatives targeting HIV-1 capsid protein. Tian BH, He MZ, Tang SX, Hewlett I, Tan ZW, Li JB, Jin YX, Yang M. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009; 19(8): 2162-2167.

17. Tricyclic HIV integrase inhibitors V. SAR studies on the benzyl moiety. Jin HL, Metobo S, Jabri S, Mish M, Lansdown R, Chen XW, Tsiang M, Wright M, Kim CU. IOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009; 19(8): 2263-2265.

18. Synthesis and biological evaluation of N-4-(hetero) arylsulfonylquinoxalinones as HIV-1 reverse transcriptase inhibitors. Xu BL, Sun Y, Guo Y, Cao YL, Yu T. BIOORGANIC & MEDICINAL CHEMISTRY, 2009; 17(7): 2767-2774.

19. Design and synthesis of novel dihydroquinoline-3-carboxylic acids as HIV-1 integrase inhibitors. Sechi M, Rizzi G, Bacchi A, Carcelli M, Rogolino D, Pala N, Sanchez TW, Taheri L, Dayam R, Neamati N. BIOORGANIC & MEDICINAL CHEMISTRY, 2009; 17(7): 2925-2935.

20. Synthesis of Some Novel Non-Nucleoside Reverse Transcriptase Inhibitor. Bapna M, Nema RK. ASIAN JOURNAL OF CHEMISTRY, 2009; 21(2): 1244-1248.

21. Indolylarylsulfones Bearing Natural and Unnatural Amino Acids.Discovery of Potent Inhibitors of HIV-1 Non-Nucleoside Wild Type and Resistant Mutant Strains Reverse Transcriptase and Coxsackie B4 Virus. Piscitelli F, Coluccia A, Brancale A, La Regina G, Sansone A, Giordano C, Balzarini J, Maga G, Zanoli S, Samuele A, Cirilli R, La Torre F, Lavecchia A, Novellino E, Silvestri R. JOURNAL OF MEDICINAL CHEMISTRY, 2009; 52(7): 1922-1934.