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ONLINE DATABASE SEARCH - HIV-LS-303-MEMO

1. 43914 HIV-LS-303; SCIFINDER-HIV-8/17/2004

Synthesis of certain 6-(arylthio)uracils and related derivatives as potential antiviral agents

El-Emam, Ali A, Massoud, Mohamed AM, El-Bendary, Eman R, and El-Sayed, Magda A

Bulletin of the Korean Chemical Society 2004. 25(7): 991-996

 

2. 43915 HIV-LS-303; PUBMED-HIV-8/24/2004

Resistance to HIV Protease Inhibitors: Mechanisms and Clinical Consequences

De Mendoza, C and Soriano, V

Curr Drug Metab 2004. 5(4): 321-328

HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15320704&dopt=abstract


3. 43916 HIV-LS-303; PUBMED-HIV-8/24/2004

Structural Determinants and Molecular Mechanisms for the Resistance of HIV-1 RT to Nucleoside Analogues

Deval, J, Courcambeck, J, Selmi, B, Boretto, J, and Canard, B

Curr Drug Metab 2004. 5(4): 305-16

HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15320702&dopt=abstract


4. 43917 HIV-LS-303; PUBMED-HIV-8/24/2004

HIV-1 Reverse Transcriptase Inhibitors: Current Issues and Future Perspectives

Locatelli, GA, Cancio, R, Spadari, S, and Maga, G

Curr Drug Metab 2004. 5(4): 283-90

HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15320700&dopt=abstract


5. 43918 HIV-LS-303; SCIFINDER-HIV-8/17/2004

Antiviral Drugs: Third strike against HIV enzymes

Kirkpatrick, Peter

Nature Reviews Drug Discovery 2004. 3(8): 645

 

6. 43919 HIV-LS-303; PUBMED-HIV-8/24/2004

Statins Inhibit HIV-1 Infection by Down-regulating Rho Activity

Del Real, G, Jimenez-Baranda, S, Mira, E, Lacalle, RA, Lucas, P, Gomez-Mouton, C, Alegret, M, Pena, JM, Rodriguez-Zapata, M, Alvarez-Mon, M, Martinez-A, C, and Manes, S

J Exp Med 2004. 200(4): 541-547

HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15314078&dopt=abstract


7. 43920 HIV-LS-303; SCIFINDER-HIV-8/17/2004

Preparation of tetrahydro-4H-pyrido[1,2-a]pyrimidines and related compounds as HIV integrase inhibitors ((Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa, Italy)

Crescenzi, Benedetta, Kinzel, Olaf, Muraglia, Ester, Orvieto, Federica, Pescatore, Giovanna, Rowley, Michael, and Summa, Vincenzo

PATENT: WO 2004058756 A1; ISSUE DATE: 20040715

APPLICATION: 2003; PP: 113 pp.

 

8. 43921 HIV-LS-303; PUBMED-HIV-8/24/2004

Synthesis and application of methyleneoxy pseudodipeptide building blocks in biologically active peptides

Hlavacek, J, Marik, J, Konvalinka, J, Bennettova, B, and Tykva, R

Amino Acids 2004. 27(1): 19-27

HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15309568&dopt=abstract


9. 43922 HIV-LS-303; PUBMED-HIV-8/24/2004

Inhibition of HIV-1 fusion with small interfering RNAs targeting the chemokine coreceptor CXCR4

Zhou, N, Fang, J, Mukhtar, M, Acheampong, E, and Pomerantz, RJ

Gene Ther 2004

HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15306840&dopt=abstract


10. 43923 HIV-LS-303; SCIFINDER-HIV-8/17/2004

Preparation of pyrrolidine and azetidine compounds as CCR5 antagonists ((Smithkline Beecham Corporation, USA)

Yang, Hanbiao, Kazmierski, Wieslaw Mieczyslaw, and Aquino, Christopher Joseph

PATENT: WO 2004055016 A1; ISSUE DATE: 20040701

APPLICATION: 2003; PP: 130 pp.

 

11. 43924 HIV-LS-303; SCIFINDER-HIV-8/17/2004

Preparation of indane compounds and analogs as CCR5 antagonists ((Smithkline Beecham Corporation, USA)

Youngman, Michael, Kazmierski, Wieslaw Mieczyslaw, Yang, Hanbiao, and Aquino, Christopher Joseph

PATENT: WO 2004055012 A1; ISSUE DATE: 20040701

APPLICATION: 2003; PP: 129 pp.

 

12. 43925 HIV-LS-303; PUBMED-HIV-8/24/2004

PHI-443: A Novel Noncontraceptive Broad-Spectrum Anti- Human Immunodeficiency Virus Microbicide

D'Cruz, OJ, Samuel, P, and Uckun, FM

Biol Reprod 2004

HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15306558&dopt=abstract


13. 43926 HIV-LS-303; PUBMED-HIV-8/24/2004

Small-Molecule Dimerization Inhibitors of Wild-Type and Mutant HIV Protease: A Focused Library Approach

Shultz, MD, Ham, YW, Lee, SG, Davis, DA, Brown, C, and Chmielewski, J

J Am Chem Soc 2004. 126(32): 9886-7

HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15303839&dopt=abstract



14. 43927 HIV-LS-303; PUBMED-HIV-8/24/2004

Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages

Emori, Y, Ikeda, T, Ohashi, T, Masuda, T, Kurimoto, T, Takei, M, and Kannagi, M

J Gen Virol 2004. 85(Pt 9): 2603-13

HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15302954&dopt=abstract


15. 43928 HIV-LS-303; PUBMED-HIV-8/24/2004

l-Chicoric acid inhibits human immunodeficiency virus type 1 integration in vivo and is a noncompetitive but reversible inhibitor of HIV-1 integrase in vitro

Reinke, RA, Lee, DJ, McDougall, BR, King, PJ, Victoria, J, Mao, Y, Lei, X, Reinecke, MG, and Robinson, WE Jr

Virology 2004. 326(2): 203-19

HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15302207&dopt=abstract


16. 43929 HIV-LS-303; PUBMED-HIV-8/24/2004

2-(2,6-Dihalophenyl)-3-(pyrimidin-2-yl)-1,3-thiazolidin-4-ones as non-nucleoside HIV-1 reverse transcriptase inhibitors

Rao, A, Balzarini, J, Carbone, A, Chimirri, A, De, Clercq E, Monforte, AM, Monforte, P, Pannecouque, C, and Zappala, M

Antiviral Res 2004. 63(2): 79-84

HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15302136&dopt=abstract


17. 43930 HIV-LS-303; PUBMED-HIV-8/24/2004

Protecting from R5-tropic HIV: individual and combined effectiveness of a hammerhead ribozyme and a single-chain Fv antibody that targets CCR5

Cordelier, P, Kulkowsky, JW, Ko, C, Matskevitch, AA, McKee, HJ, Rossi, JJ, Bouhamdan, M, Pomerantz, RJ, Kari, G, and Strayer, DS

Gene Ther 2004

HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15295615&dopt=abstract


18. 43931 HIV-LS-303; SCIFINDER-HIV-8/17/2004

Preparation of 5,11-dihydro-8-(2-hydroxyethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one derivatives as non-nucleoside reverse transcriptase inhibitors ((Boehringer Ingelheim (Canada) Ltd., Can.)

Yoakim, Christiane, Malenfant, Eric, Thavonekham, Bounkham, Ogilvie, William, and Deziel, Robert

PATENT: US 2004106791 A1; ISSUE DATE: 20040603

APPLICATION: 2003-7496; PP: 27 pp.

 

19. 43932 HIV-LS-303; PUBMED-HIV-8/24/2004

Lamellarins, from A to Z: a family of anticancer marine pyrrole alkaloids

Bailly, C

Curr Med Chem Anti-Canc Agents 2004. 4(4): 363-78

HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15281908&dopt=abstract


20. 43933 HIV-LS-303; SCIFINDER-HIV-8/17/2004

Quinolones with anti-HIV activity, and preparation thereof ((IRM LLC, Bermuda)

He, Yun, Ellis, David Archer, Anaclerio, Beth Marie, Kuhen, Kelli L, Wu, Baogen, and Jiang, Tao

PATENT: WO 2004037853 A2; ISSUE DATE: 20040506

APPLICATION: 2003; PP: 71 pp.

 

21. 43934 HIV-LS-303; SCIFINDER-HIV-8/17/2004

Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir

Tuske, Steve, Sarafianos, Stefan G, Clark, Arthur D, Ding, Jianping, Naeger, Lisa K, White, Kirsten L, Miller, Michael D, Gibbs, Craig S, Boyer, Paul L, Clark, Patrick, Wang, Gang, Gaffney, Barbara L, Jones, Roger A, Jerina, Donald M, Hughes, Stephen H, and Arnold, Eddy

Nature Structural & Molecular Biology 2004. 11(5): 469-474

 

22. 43935 HIV-LS-303; SCIFINDER-HIV-8/17/2004

Use of soluble monovalent oligosaccharides as inhibitors of HIV-1 fusion and replication((USA))

Leach, James L, Garber, Stacey Ann, Prieto, Pedro A, Alarcon, Balbino, Rueda, Ricardo, and Vazquez, Enrique

PATENT: US 2004077590 A1; ISSUE DATE: 20040422

APPLICATION: 2002-15115; PP: 13 pp.

 

23. 43936 HIV-LS-303; PUBMED-HIV-8/24/2004

Drug Targeting of HIV-1 RNA.DNA Hybrid Structures: Thermodynamics of Recognition and Impact on Reverse Transcriptase-Mediated Ribonuclease H Activity and Viral Replication

Li, TK, Barbieri, CM, Lin, HC, Rabson, AB, Yang, G, Fan, Y, Gaffney, BL, Jones, RA, and Pilch, DS

Biochemistry 2004. 43(30): 9732-9742

HYPERLINK:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15274628&dopt=abstract


24. 43937 HIV-LS-303; SCIFINDER-HIV-8/17/2004

Short-term safety and antiretroviral activity of T-1249, a second-generation fusion inhibitor of HIV

Eron, Joseph J, Gulick, Roy M, Bartlett, John A, Merigan, Thomas, Arduino, Roberto, Kilby, JMichael, Yangco, Bienvenido, Diers, Adriann, Drobnes, Claude, DeMasi, Ralph, Greenberg, Michael, Melby, Thomas, Raskino, Claire, Rusnak, Pam, Zhang, Ying, Spence, Rebecca, and Miralles, GDiego

Journal of Infectious Diseases 2004. 189(6): 1075-1083

 

25. 43938 HIV-LS-303; SCIFINDER-HIV-8/17/2004

Antiviral random sequence oligonucleotides lacking complementarity to target genomes and their therapeutic uses ((Replicor, Inc. Can.)

Vaillant, Andrew and Juteau, Jean-Marc

PATENT: WO 2004024919 A1; ISSUE DATE: 20040325

APPLICATION: 2003; PP: 161 pp.

 

26. 43939 HIV-LS-303; WOS-HIV-8/15/2004

The HIV protease inhibitor ritonavir blocks osteoclastogenesis and function by impairing RANKL-induced signaling

Wang, MWH, Wei, S, Faccio, R, Takeshita, S, Tebas, P, Powderly, WG, Teitelbaum, SL, and Ross, FP

J CLIN INVEST 2004. 114(2): 206-213

HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000222667600011


27. 43940 HIV-LS-303; WOS-HIV-8/15/2004

Exploring binding mode for styrylquinoline HIV-1 integrase inhibitors using comparative molecular field analysis and docking studies

Ma, XH, Zhang, XY, Tan, JJ, Chen, WZ, and Wang, CX

ACTA PHARMACOL SIN 2004. 25(7): 950-958

HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000222574700016


28. 43941 HIV-LS-303; WOS-HIV-8/23/2004

Improved preparation and structural investigation of 4-aryl-4-oxo-2-hydroxy-2-butenoic acids and methyl esters

Maurin, C, Bailly, F, and Cotelle, P

TETRAHEDRON 2004. 60(31): 6479-6486

HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000222863600007


29. 43942 HIV-LS-303; WOS-HIV-8/23/2004

In-water reactivity of nucleosides and nucleotides: one-step preparation and biological evaluation of novel ferrocenyl-derivatives

de Champdore, M, Di Fabio, G, Messere, A, Montesarchio, D, Piccialli, G, Loddo, R, La Colla, M, and La Colla, P

TETRAHEDRON 2004. 60(31): 6555-6563

HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000222863600015


30. 43943 HIV-LS-303; WOS-HIV-8/23/2004

Synthesis of peptidomimetics based on iminosugar and beta-D-glucopyranoside scaffolds and inhibiton of HIV-protease

Chery, F, Cronin, L, O'Brien, JL, and Murphy, PV

TETRAHEDRON 2004. 60(31): 6597-6608

HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000222863600021


31. 43944 HIV-LS-303; WOS-HIV-8/23/2004

Actinchinin, a novel antifungal protein from the gold kiwi fruit

Xia, LX and Ng, TB

PEPTIDES 2004. 25(7): 1093-1098

HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000222855100004


32. 43945 HIV-LS-303; WOS-HIV-8/23/2004

Expression of HIV-1 accessory protein Vif is controlled uniquely to be low and optimal by proteasome degradation

Fujita, M, Akari, H, Sakurai, A, Yoshida, A, Chiba, T, Tanaka, K, Strebel, K, and Adachi, A

MICROBES INFECT 2004. 6(9): 791-798

HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000222860200001


33. 43946 HIV-LS-303; WOS-HIV-8/23/2004

Lysine sulfonamides as novel HIV-protease inhibitors: N epsilon-disubstituted ureas

Stranix, BR, Sauve, G, Bouzide, A, Cote, A, Sevigny, G, Yelle, J, and Perron, V

BIOORG MED CHEM LETT 2004. 14(15): 3971-3974

HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000222792800025


34. 43947 HIV-LS-303; WOS-HIV-8/23/2004

Rigid backbone moiety of KNI-272, a highly selective HIV protease inhibitor: methanol, acetone and dimethylsulfoxide solvated forms of 3-[3-benzyl-2-hydroxy-9-(isoquinoli -5-yloxy)-6-methyl-sulfanylmethyl-5 8-dioxo-4,7-diazanonanoyl]-N-tert-b tyl-1,3-thiazolidine-4-carboxamide

Doi, M, Kimura, T, Ishida, T, and Kiso, Y

ACTA CRYSTALLOGR B 2004. 60: 433-437

HYPERLINK:

http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000222725100009


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