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ONLINE DATABASE SEARCH - HIV-LS-293-MEMO

1. 43118 HIV-LS-293; PUBMED-HIV-4/7/2003

Preparation and antiviral properties of new acyclic, achiral nucleoside analogues: 1- or 9-[3-hydroxy-2-(hydroxymethyl)prop-1-enyl]nucleobases and 1- or 9-[2,3-dihydroxy-2-(hydroxymethyl)propyl]nucleobases

Boesen, T, Madsen, C, Sejer, Pedersen D, Nielsen, BM, Petersen, AB, Petersen, MA , Munck, M, Henriksen, U, Nielsen, C, and Dahl, O

Org Biomol Chem 2004. 2(8): 1245-1254

HYPERLINK:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15064804&dopt=abstract


2. 43119 HIV-LS-293; PUBMED-HIV-4/7/2003

Activity of the isolated HIV RNase H domain and specific inhibition by N-hydroxyimides

Hang, JQ, Rajendran, S, Yang, Y, Li, Y, Wong, Kai In P, Overton, H, Parkes, KE, Cammack, N, Martin, JA, and Klumpp, K

Biochem Biophys Res Commun 2004. 317(2): 321-9

HYPERLINK:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15063760&dopt=abstract


3. 43120 HIV-LS-293; PUBMED-HIV-4/7/2003

Human immunodeficiency virus type 1 inhibitory activity of Mentha longifolia

Amzazi, S, Ghoulami, S, Bakri, Y, Il, Idrissi A, Fkih-Tetouani, S, and Benjouad, A

Therapie 2003. 58(6): 531-4

HYPERLINK:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15058498&dopt=abstract


4. 43121 HIV-LS-293; PUBMED-HIV-4/7/2003

Inhibition of HIV-1 Reverse Transcriptase and Protease by Phlorotannins from the Brown Alga Ecklonia cava

Ahn, MJ, Yoon, KD, Min, SY, Lee, JS, Kim, JH, Kim, TG, Kim, SH, Kim, NG, Huh, H, and Kim, J

Biol Pharm Bull 2004. 27(4): 544-7

HYPERLINK:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15056863&dopt=abstract


5. 43122 HIV-LS-293; PUBMED-HIV-4/7/2003

Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins

Si, Z, Madani, N, Cox, JM, Chruma, JJ, Klein, JC, Schon, A, Phan, N, Wang, L, Biorn, AC, Cocklin, S, Chaiken, I, Freire, E, Smith, AB 3rd, and Sodroski, JG

Proc Natl Acad Sci U S A 2004. 101(14): 5036-5041

HYPERLINK:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15051887&dopt=abstract


6. 43123 HIV-LS-293; PUBMED-HIV-4/7/2003

Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondrial DNA polymerase

Feng, JY, Murakami, E, Zorca, SM, Johnson, AA, Johnson, KA, Schinazi, RF, Furman, PA, and Anderson, KS

Antimicrob Agents Chemother 2004. 48(4): 1300-6

HYPERLINK:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15047533&dopt=abstract


7. 43124 HIV-LS-293; PUBMED-HIV-4/7/2003

HIV-1 protease molecular dynamics of a wild-type and of the V82F/I84V mutant: possible contributions to drug resistance and a potential new target site for drugs

Perryman, AL, Lin, JH, and McCammon, JA

Protein Sci 2004. 13(4): 1108-23

HYPERLINK:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15044738&dopt=abstract


8. 43125 HIV-LS-293; SCIFINDER-HIV-3/30/2004

Six-week randomized controlled trial to compare the tolerabilities, pharmacokinetics, and antiviral activities of GW433908 and amprenavir in human immunodeficiency virus type 1-infected patients

Wood, Robin, Arasteh, Keikawus, Stellbrink, Hans-juergen, Teofilo, Eugenio, Raffi, Francois, Pollard, Richard B, Eron, Joseph, Yeo, Jane, Millard, Judith, Wire, Mary Beth, and Naderer, Odin J

Antimicrobial Agents and Chemotherapy 2004. 48(1): 116-123

 

9. 43126 HIV-LS-293; PUBMED-HIV-4/7/2003

Nucleosides. IX. Synthesis of purine N(3),5'-cyclonucleosides and N(3),5'-cyclo-2',3'-seconucleosides via Mitsunobu reaction as TIBO-like derivatives

Chen, GS, Chen, CS, Chien, TC, Yeh, JY, Kuo, CC, Talekar, RS, and Chern, JW

Nucleosides Nucleotides Nucleic Acids 2004. 23(1-2): 347-59

HYPERLINK:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15043159&dopt=abstract


10. 43127 HIV-LS-293; SCIFINDER-HIV-3/30/2004

Heterocyclic compound having hiv integrase inhibitory activity((Shionogi & Co., Ltd. Japan)

Murai, Hitoshi, Endo, Takeshi, Kurose, Noriyuki, Taishi, Teruhiko, and Yoshida, Hiroshi

PATENT: WO 2004024693 A1; ISSUE DATE: 20040325

APPLICATION: 2003; PP: 396 pp.

 

11. 43128 HIV-LS-293; SCIFINDER-HIV-3/30/2004

Dihydroxypyridopyrazine-1,6-dione compounds useful as HIV integrase inhibitors((Merck & Co., Inc. USA)

Wai, John S, Kim, Boyoung, Fisher, Thorsten E, Zhuang, Linghang, Williams, Peter D, Lyle, Terry A, Langford, HMarie, and Robinson, Kyle A

PATENT: WO 2004024078 A2; ISSUE DATE: 20040325

APPLICATION: 2003; PP: 137 pp.

 

12. 43129 HIV-LS-293; PUBMED-HIV-4/7/2003

A new approach for the synthesis of novel 5-substituted isodeoxyuridine analogs

Guenther, S and Nair, V

Nucleosides Nucleotides Nucleic Acids 2004. 23(1-2): 183-93

HYPERLINK:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15043146&dopt=abstract


13. 43130 HIV-LS-293; PUBMED-HIV-4/7/2003

Nucleosides. LXV. Synthesis of new pteridine-N8-nucleosides

Matysiak, S, Waldscheck, B, and Pfleiderer, W

Nucleosides Nucleotides Nucleic Acids 2004. 23(1-2): 51-66

HYPERLINK:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15043136&dopt=abstract


14. 43131 HIV-LS-293; PUBMED-HIV-4/7/2003

Synthesis and antiviral activity of novel fluorinated 2',3'-dideoxynucleosides

Kumar, P, Ohkura, K, Balzarini, J, De Clercq, E, Seki, K, and Wiebe, LI

Nucleosides Nucleotides Nucleic Acids 2004. 23(1-2): 7-29

HYPERLINK:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15043133&dopt=abstract


15. 43132 HIV-LS-293; SCIFINDER-HIV-3/30/2004

Understanding the integrase inhibitory activity of azido containing HIV-1 integrase inhibitors

Karki, Rajeshri G and Nicklaus, Marc C

CONFERENCE: Abstracts of Papers, 227th ACS National Meeting, Anaheim, CA, United States, March 28-April 1, 2004 2004: MEDI-017

 

16. 43133 HIV-LS-293; SCIFINDER-HIV-3/30/2004

Bis-Ketol Nucleoside Triesters as Prodrugs of the Antiviral Nucleoside Triphosphate Analogues of 3'-Deoxythymidine and 3'-Deoxy-2',3'-didehydrothymidine

Calvo, Kim C, Wang, Xiaohong, and Koser, Gerald F

Nucleosides, Nucleotides & Nucleic Acids 2004. 23(3): 637-646

 

17. 43134 HIV-LS-293; PUBMED-HIV-4/7/2003

Susceptibility of HIV-2, SIV and SHIV to various anti-HIV-1 compounds: implications for treatment and postexposure prophylaxis

Witvrouw, M, Pannecouque, C, Switzer, WM, Folks, TM, De Clercq, E, and Heneine, W

Antivir Ther 2004. 9(1): 57-65

HYPERLINK:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15040537&dopt=abstract


18. 43135 HIV-LS-293; PUBMED-HIV-4/7/2003

Antiretroviral drug resistance in non-subtype B HIV-1, HIV-2 and SIV

Parkin, NT and Schapiro, JM

Antivir Ther 2004. 9(1): 3-12

HYPERLINK:  http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15040531&dopt=abstract


19. 43136 HIV-LS-293; SCIFINDER-HIV-3/30/2004

Synthesis and antimicrobial activity of some novel 6-bromo-2-methyl/phenyl-3-(sulphonamido) quinazolin-4(3H)-ones

Selvam, P, Vanitha, K, Chandramohan, M, and De Clerco, E

Indian Journal of Pharmaceutical Sciences 2004. 66(1): 82-86

 

20. 43137 HIV-LS-293; SCIFINDER-HIV-3/30/2004

Phosphatidylinositol 3,5-biphosphate inhibitors as antiviral agents((Piramed Limited, UK)

Parker, Peter and Waterfield, Michael

PATENT: WO 2004017950 A2; ISSUE DATE: 20040304

APPLICATION: 2003; PP: 56 pp.

 

21. 43138 HIV-LS-293; SCIFINDER-HIV-3/30/2004

Use of inhibitors of acid sphingomyelinase and of acid sphingomyelinase reaction products for the prophylaxis and treatment of infectious diseases((Gulbins, Erich Germany)

PATENT: DE 10239531 A1; ISSUE DATE: 20040304

APPLICATION: 2002; PP: 10 pp.

 

22. 43139 HIV-LS-293; SCIFINDER-HIV-3/30/2004

Non-peptidic protease inhibitors (NPPIs): Tipranavir

Mayers, Douglas, Curry, Kevin, Kohlbrenner, Veronika, and McCallister, Scott

Advances in Antiviral Drug Design 2004. 4: 79-98

 

23. 43140 HIV-LS-293; SCIFINDER-HIV-3/30/2004

Broad spectrum substituted oxindole sulfonamide HIV protease inhibitors((Tibotec Pharmaceuticals Ltd., Ire.)

Tahri, Abdellah and Wigerinck, Piet Tom Bert Paul

PATENT: WO 2004016619 A1; ISSUE DATE: 20040226

APPLICATION: 2003; PP: 53 pp.

 

24. 43141 HIV-LS-293; SCIFINDER-HIV-3/30/2004

Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition

Das, Atze T, Brummelkamp, Thijn R, Westerhout, Ellen M, Vink, Monique, Madiredjo, Mandy, Bernards, Rene, and Berkhout, Ben

Journal of Virology 2004. 78(5): 2601-2605

 

25. 43142 HIV-LS-293; SCIFINDER-HIV-3/30/2004

Broad-spectrum 2-aminobenzothiazole sulfonamide HIV protease inhibitors((Tibotec Pharmaceuticals Ltd., Ire.)

Surleraux, Dominique Louis Nestor Ghislain, Wigerinck, Piet Tom Bert Paul, and Getman, Daniel P

PATENT: WO 2004014371 A1; ISSUE DATE: 20040219

APPLICATION: 2003; PP: 44 pp.

 

26. 43143 HIV-LS-293; SCIFINDER-HIV-3/30/2004

In vitro activity of stampidine against primary clinical human immunodeficiency virus isolates

Uckun, Fatih M, Pendergrass, Sharon, Qazi, Sanjive, and Venkatachalam, Taracad K

Arzneimittel Forschung 2004. 54(1): 69-77

 

27. 43144 HIV-LS-293; SCIFINDER-HIV-3/30/2004

Preparation of PEGylated T1249 polypeptide conjugates as antiviral agents((F. Hoffmann-La Roche AG, Switz.)

Bailon, Pascal Sebastian and Won, Chee-Youb

PATENT: WO 2004013165 A1; ISSUE DATE: 20040212

APPLICATION: 2003; PP: 61 pp.

 

28. 43145 HIV-LS-293; SCIFINDER-HIV-3/30/2004

Antiviral pyrazines and pharmaceutical compositions containing them((Toyama Chemical Co., Ltd. Japan)

Egawa, Hiroyuki, Sugita, Atsushi, and Furuta, Yosuke

PATENT: JP 2004043371 A2; ISSUE DATE: 20040212

APPLICATION: 2002-7517; PP: 41 pp.

 

29. 43146 HIV-LS-293; SCIFINDER-HIV-3/30/2004

Preparation of N-(4-piperidinyl) amide compounds as chemokine receptor CCR5 modulators((AstraZeneca AB, Swed.)

Cumming, John and Winter, Jon

PATENT: WO 2004018425 A1; ISSUE DATE: 20040304

APPLICATION: 2003; PP: 43 pp.

 

30. 43147 HIV-LS-293; WOS-HIV-3/28/2004

Quality assurance program for clinical measurement of antiretrovirals: AIDS Clinical Trials Group proficiency testing program for pediatric and adult pharmacology laboratories

Holland, DT, DiFrancesco, R, Stone, J, Hamzeh, F, Connor, JD, and Morse, GD

ANTIMICROB AGENTS CH 2004. 48(3): 824-831

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000189351700018


31. 43148 HIV-LS-293; WOS-HIV-3/28/2004

3 ' R,4 ' R-Di-(O)-(-)-camphanoyl-2 ',2 '-dimethyl-dihydropyrano [2,3-F]-chromone (DCP): A novel class of potent anti-HIV agents.

Yu, DL, Brossi, A, and Lee, KH

ABSTR PAP AM CHEM S 2003. 225: U179

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000187918000961


32. 43149 HIV-LS-293; WOS-HIV-3/28/2004

Synthesis of enantiomerically pure D-FDOC and its anti-HIV activity.

Mao, SL, Liotta, DC, Bouygues, M, Welch, CJ, Biba, M, and Schinazi, RF

ABSTR PAP AM CHEM S 2003. 225: U231

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000187918001244


33. 43150 HIV-LS-293; WOS-HIV-3/28/2004

Synthesis of modified nucleoside analogues as anti-HIV agents.

Reddy, VD

ABSTR PAP AM CHEM S 2003. 226: U210-U211

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000187062400912


34. 43151 HIV-LS-293; WOS-HIV-3/28/2004

How a modification (8-aza-3-deaza-2 '-deoxyguanosine) influences the quadruplex structure of Hotoda's 6-mer TGGGAG with 5 '- and 3 '-end modifications

Jaksa, S, Kralj, B, Pannecouque, C, Balzarini, J, De, Clercq E, and Kobe, J

NUCLEOS NUCLEOT NUCL 2004. 23(1-2): 77-88

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220148100008


35. 43152 HIV-LS-293; WOS-HIV-3/28/2004

Second generation of cycloSal-pronucleotides with esterase-cleavable sites: The "lock-in"-concept

Meier, C, Ruppel, MFH, Vukadinovic, D, and Balzarini, J

NUCLEOS NUCLEOT NUCL 2004. 23(1-2): 89-115

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220148100009


36. 43153 HIV-LS-293; WOS-HIV-3/28/2004

Synthesis and evaluation of a novel synthetic phosphocholine lipid-AZT conjugate that double-targets wild-type and drug resistant variants of HIV

Kucera, LS, Morris-Natschke, SL, Ishaq, KS, Hes, J, Iyer, N, Furman, PA, and Fleming, RA

NUCLEOS NUCLEOT NUCL 2004. 23(1-2): 385-399

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220148100032


37. 43154 HIV-LS-293; WOS-HIV-3/28/2004

Retinoid-dependent restriction of human immunodeficiency virus type 1 replication in monocytes/macrophages

Hanley, TM, Kiefer, HLB, Schnitzler, AC, Marcello, JE, and Viglianti, GA

J VIROL 2004. 78(6): 2819-2830

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220043100017


38. 43155 HIV-LS-293; WOS-HIV-3/28/2004

New 2,4-diamino-5-(2 ',5 '-substituted benzyl)pyrimidines as potential drugs against opportunistic infections of AIDS and other immune disorders. Synthesis and species-dependent antifolate activity

Rosowsky, A, Forsch, RA, Sibley, CH, Inderlied, CB, and Queener, SF

J MED CHEM 2004. 47(6): 1475-1486

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220038700018


39. 43156 HIV-LS-293; WOS-HIV-4/4/2004

Synthesis of AZT/d4T boranophosphates as anti-HIV prodrug candidates

Lin, CX, Fu, H, Tu, GZ, and Zhao, YF

SYNTHESIS-STUTTGART 2004(4): 509-516

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220191300007


40. 43157 HIV-LS-293; WOS-HIV-4/4/2004

HIV protease inhibitor part 1: Use of Evans' oxazolidinone in intermolecular Diels-Alder reaction en route to 3,4-substituted cyclohexanones

Crackett, P, Demont, E, Eatherton, A, Frampton, CS, Gilbert, J, Kahn, I, Redshaw, S, and Watson, W

SYNLETT 2004(4): 679-683

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220191700021


41. 43158 HIV-LS-293; WOS-HIV-4/4/2004

HIV protease inhibitors part 2: [3+2] cycloaddition, isomerization; and ring expansion en route to 4,5-substituted cyclohexenones

Demont, E, Eatherton, A, Frampton, CS, Kahn, I, and Redshaw, S

SYNLETT 2004(4): 684-687

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220191700022


42. 43159 HIV-LS-293; WOS-HIV-4/4/2004

Novel peptide-based HIV-1 immunotherapy

Sommerfelt, MA, Nyhus, J, and Sorensen, B

EXPERT OPIN BIOL TH 2004. 4(3): 349-361

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220193400008


43. 43160 HIV-LS-293; WOS-HIV-4/4/2004

Novel phosphonate nucleosides as antiviral agents

Hwang, JT and Choi, JR

DRUG FUTURE 2004. 29(2): 163-177

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220229600007


44. 43161 HIV-LS-293; WOS-HIV-4/4/2004

Co-receptor antagonists as HIV-1 entry inhibitors

Shaheen, F and Collman, RG

CURR OPIN INFECT DIS 2004. 17(1): 7-16

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220248300002


45. 43162 HIV-LS-293; WOS-HIV-4/4/2004

Synthesis and in vitro evaluation of S-acyl-3-thiopropyl prodrugs of Foscarnet

Gagnard, V, Leydet, A, Morere, A, Montero, JL, Lefebvre, I, Gosselin, G, Pannecouque, C, and De, Clercq E

BIOORGAN MED CHEM 2004. 12(6): 1393-1402

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220237800014


46. 43163 HIV-LS-293; WOS-HIV-4/4/2004

HIV-2 protease sequences of subtypes A and B harbor multiple mutations associated with protease inhibitor resistance in HIV-1

Pieniazek, D, Rayfield, M, Hu, DJ, Nkengasong, JN, Soriano, V, Heneine, W, Zeh, C, Agwale, SM, Wambebe, C, Odama, L, Wiktor, SZ, and Kalish, ML

AIDS 2004. 18(3): 495-502

HYPERLINK:  http://publishorperish.nih.gov/isicgi/gateway/Gateway.cgi?KeyUT=000220233000016

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