1. Synthesis and Antiviral Evaluation of (1,4-Disubstituted-1,2,3-triazol)-(E)-2-methyl-but-2-enyl Nucleoside Phosphonate Prodrugs. Abuduaini, T., V. Roy, J. Marlet, C. Gaudy-Graffin, D. Brand, C. Baronti, F. Touret, B. Coutard, T.R. McBrayer, R.F. Schinazi, and L.A. Agrofoglio. Molecules, 2021. 26(5): 1493. PMID[33803417]. PMCID[PMC7967160].
[PubMed]. HBV_04_2021.
2. Treatment with the Immunomodulator AIC649 in Combination with Entecavir Produces Antiviral Efficacy in the Woodchuck Model of Chronic Hepatitis B. Korolowicz, K.E., M. Suresh, B. Li, X. Huang, C. Yon, X. Leng, B.V. Kallakury, R.D. Tucker, and S. Menne. Viruses, 2021. 13(4): 648. PMID[33918831]. PMCID[PMC8069054].
[PubMed]. HBV_04_2021.
3. The Functional and Antiviral Activity of Interferon Alpha-inducible IFI6 against Hepatitis B Virus Replication and Gene Expression. Sajid, M., H. Ullah, K. Yan, M. He, J. Feng, M.A. Shereen, R. Hao, Q. Li, D. Guo, Y. Chen, and L. Zhou. Frontiers in Immunology, 2021. 12: 634937. PMID[33868257]. PMCID[PMC8047077].
[PubMed]. HBV_04_2021.
4. Discovery of New Small Molecule Hits as Hepatitis B Virus Capsid Assembly Modulators: Structure and Pharmacophore-based Approaches. Senaweera, S., H. Du, H. Zhang, K.A. Kirby, P.R. Tedbury, J. Xie, S.G. Sarafianos, and Z. Wang. Viruses, 2021. 13(5): 770. PMID[33925540].
[PubMed]. HBV_04_2021.
5. Anti-HBV Activities of Polysaccharides from Thais clavigera (Küster) by in Vitro and in Vivo Study. Tang, F., G. Huang, L. Lin, H. Yin, L. Shao, R. Xu, and X. Cui. Marine Drugs, 2021. 19(4): 195. PMID[33808126]. PMCID[PMC8066037].
[PubMed]. HBV_04_2021.
6. Antiviral Activity of Interferon Alpha-inducible Protein 27 against Hepatitis B Virus Gene Expression and Replication. Ullah, H., M. Sajid, K. Yan, J. Feng, M. He, M.A. Shereen, Q. Li, T. Xu, R. Hao, D. Guo, Y. Chen, L. Zhou, and L. Zhou. Frontiers in Microbiology, 2021. 12: 656353. PMID[33868214]. PMCID[PMC8044325].
[PubMed]. HBV_04_2021.
7. SAMD4 Family Members Suppress Human Hepatitis B Virus by Directly Binding to the Smaug Recognition Region of Viral RNA. Wang, Y., X. Fan, Y. Song, Y. Liu, R. Liu, J. Wu, X. Li, Q. Yuan, G. Fu, N. Xia, and J. Han. Cellular & Molecular Immunology, 2021. 18(4): p. 1032-1044. PMID[32341522]. PMCID[PMC7223975].
[PubMed]. HBV_04_2021.
8. Discovery of Novel HBV Capsid Assembly Modulators by Structure-based Virtual Screening and Bioassays. Wang, Y., Z. Wang, J. Liu, Y. Wang, R. Wu, R. Sheng, and T. Hou. Bioorganic & Medicinal Chemistry, 2021. 36: 116096. PMID[33721800].
[PubMed]. HBV_04_2021.
Patent Citations
9. Preparation of Substituted Pyrimidines as cccDNA Inhibitors for the Treatment and Prophylaxis of Hepatitis B Virus Infection. Chen, D., W. Chen, S. Feng, C. Li, Z. Qiu, X. Tan, and G. Wu. Patent. 2021. 2020-EP77041 2021063856: 80pp.
[Patent]. HBV_04_2021.
10. Tenofovir Derivatives as Antiviral Agents and Their Preparation, Pharmaceutical Compositions and Use in the Treatment of HBV, HDV and/or HIV. Dousson, C.B. and D. Dukhan. Patent. 2021. 2020-EP79330 2021074443: 131pp.
[Patent]. HBV_04_2021.