Anti-HIV Enzyme Inhibition Data

This database contains approximately 25,000 lines of data linked to 13,000 compounds. The database was derived from the literature, patents and meeting abstracts and contains inhibitory and enzymatic data (i.e. IC50, Ki, Km, etc) on compounds tested against viral and relevant cellular enzymes and receptors.

The viral enzymes include reverse transcriptase (RT), protease (PR) and integrase (INTG). The cellular enzymes include DNA polymerases, proteases (i.e. pepsin, renin, etc), cyclophillin and a number of protein kinases. The viral and cellular receptors include GP120, GP41, Tat, Rev, NCp7, CXCR4, CCR5 and CD4.

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