ONLINE DATABASE SEARCH - OI-LS-379-MEMO

 

1.     61356   OI-LS-379; SCIFINDER-OI-7/16/2007

          Compositions and methods using carbon monoxide dehydrogenase inhibitors for the prevention, treatment and detection of tuberculosis and other diseases

          Leishman, Kathryn

          PATENT:  US 2007148689  ISSUE DATE:  20070628

          APPLICATION: 2007-48436  PP: 21pp., Cont.-in-part of U.S. Ser. No. 265,190.

          ASSIGNEE:  (USA)

          View Data on the NIAID Therapeutics Website
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2.     61357   OI-LS-379; WOS-OI-7/13/2007

          Novel Simple Efficient Synthetic Approach Toward 6-Substituted-2h-[1,2,4]Triazolo[3,4-B][1,3,4]Thiadiazole-3-Thiones and First Synthesis and Biological Evaluation of N- and S-Beta-D-Glucosides of the [1,2,4]Triazolo[3,4-B][1,3,4]Thiadiazole Ring System

          Khalil, N.

          Nucleosides Nucleotides & Nucleic Acids 2007.  26(4): 347-359

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246536100003

3.     61358   OI-LS-379; SCIFINDER-OI-7/16/2007

          Synthesis of novel substituted pyrazolyl-2-toluidinomethanethione and pyrazolyl-2-methoxyanilinomethanethione as potential antitubercular agents

          Ali, Mohamed Ashraf and Yar, Mohammad Shahar

          Acta Pol. Pharm. 2007.  64(2): 139-146

          View Data on the NIAID Therapeutics Website
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4.     61359   OI-LS-379; SCIFINDER-OI-7/16/2007

          Synthesis and antitubercular activity of substituted novel pyrazoline derivatives

          Ali Mohamed Ashraf, Yar Mohammad Shahar, Kumar Mahesh, and Pandian Ganesan Suresh

          Nat Prod Res 2007.  21(7): 575-9.

          View Data on the NIAID Therapeutics Website
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5.     61360   OI-LS-379; SCIFINDER-OI-7/16/2007

          Antimycobacterial activity of novel 1-(5-cyclobutyl-1,3-oxazol-2-yl)-3-(sub)phenyl/pyridylthiourea compounds endowed with high activity toward multidrug-resistant Mycobacterium tuberculosis

          Sriram Dharmarajan, Yogeeswari Perumal, Dinakaran Murugesan, and Thirumurugan Rathinasababathy

          J Antimicrob Chemother 2007.  59(6): 1194-6.

          View Data on the NIAID Therapeutics Website
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6.     61361   OI-LS-379; SCIFINDER-OI-7/16/2007

          Novel Boron-Containing, Nonclassical Antifolates: Synthesis and Preliminary Biological and Structural Evaluation

          Reynolds, Robert C, Campbell, Shiela R, Fairchild, Ralph G, Kisliuk, Roy L, Micca, Peggy L, Queener, Sherry F, Riordan, James M, Sedwick, WDavid, Waud, William R, Leung, Adelaine KW, Dixon, Richard W, Suling, William J, and Borhani, David W

          J. Med. Chem. 2007.  50(14): 3283-3289

          View Data on the NIAID Therapeutics Website
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7.     61362   OI-LS-379; SCIFINDER-OI-7/16/2007

          Synthesis and antifungal activity of triazole derivatives with side chain containing tert-butyl and 4-substituted-piperazin-1-yl

          He, Qiu-qin, Liu, Chao-mei, Li, Ke, Cao, Yong-bing, Zhao, Li-hua, and Dong, Huan-wen

          Dier Junyi Daxue Xuebao 2007.  28(2): 179-182

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8.     61363   OI-LS-379; SCIFINDER-OI-7/16/2007

          Bioassay-guided isolation of antifungal alkaloids from Melochia odorata

          Emile, Aurelie, Waikedre, Jean, Herrenknecht, Christine, Fourneau, Christophe, Gantier, Jean-Charles, Hnawia, Edouard, Cabalion, Pierre, Hocquemiller, Reynald, and Fournet, Alain

          Phytother. Res. 2007.  21(4): 398-400

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9.     61364   OI-LS-379; WOS-OI-7/13/2007

          Pharmacokinetics and Metabolism of the Prodrug Db289 (2,5-Bis[4-(N-Methoxyamidino)Phenyl]Furan Monomaleate) in Rat and Monkey and Its Conversion to the Antiprotozoal/Antifungal Drug Db75 (2,5-Bis(4-Guanylphenyl)Furan Dihydrochloride)

          Midgley, I. et al.

          Drug Metabolism and Disposition 2007.  35(6): 955-967

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246596700016

10.   61365   OI-LS-379; SCIFINDER-OI-7/16/2007

          Antiviral 2-carboxy-thiophene compounds

          Corfield, John Andrew, Grimes, Richard Martin, Harrison, David, Hartley, Charles David, Howes, Peter David, Le, Joelle, Meeson, Malcolm Lees, Mordaunt, Jacqueline Elizabeth, Shah, Pritom, Slater, Martin John, and White, Gemma Victoria

          PATENT:  WO 2007071434  ISSUE DATE:  20070628

          APPLICATION: 2006  PP: 155pp.

          ASSIGNEE:  (Smithkline Beecham Corporation, USA

          View Data on the NIAID Therapeutics Website
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11.   61366   OI-LS-379; WOS-OI-7/20/2007

          Qsar Study of Antimicrobial Activity of Some 3-Nitrocoumarins and Related Compounds

          Debeljak, Z. et al.

          Journal of Chemical Information and Modeling 2007.  47(3): 918-926

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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246776400025

12.   61367   OI-LS-379; WOS-OI-7/20/2007

          Investigation of Beta-Amino Acids as Building Blocks in Hepatitis C Virus Ns3 Protease Inhibitors

          Nurbo, J. et al.

          Biopolymers 2007.  88(4): 580

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000247425900269

13.   61368   OI-LS-379; WOS-OI-7/20/2007

          Amper: a Database and an Automated Discovery Tool for Antimicrobial Peptides

          Fjell, C., Hancock, R., and Cherkasov, A.

          Bioinformatics  2007.  23(9): 1148-1155

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246773300014


14.   61369   OI-LS-379; PUBMED-OI-7/23/2007

          Barriers to reaching the targets for tuberculosis control: multidrug-resistant tuberculosis

          Blondal, K

          Bull World Health Organ 2007.  85(5): 387-390

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17639225&dopt=abstract

15.   61370   OI-LS-379; PUBMED-OI-7/23/2007

          Reaching the targets for tuberculosis control: the impact of HIV

          Laserson, K and Wells, C

          Bull World Health Organ 2007.  85(5): 377-381

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17639223&dopt=abstract

16.   61371   OI-LS-379; PUBMED-OI-7/23/2007

          Did we reach the 2005 targets for tuberculosis control?

          Dye, C, Hosseini, M, and Watt, C

          Bull World Health Organ 2007.  85(5): 364-369

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17639221&dopt=abstract

17.   61372   OI-LS-379; PUBMED-OI-7/23/2007

          A New Dihydroagarofuranoid Sesquiterpene from Microtropis fokienensis with Antituberculosis Activity

          Chou, TH, Chen, IS, Sung, PJ, Peng, CF, Shieh, PC, and Chen, JJ

          Chem Biodivers  2007.  4(7): 1594-1600

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17638341&dopt=abstract

18.   61373   OI-LS-379; PUBMED-OI-7/23/2007

          New Insight into the Mechanism of Action of and Resistance to Isoniazid: Interaction of Mycobacterium tuberculosis enoyl-ACP Reductase with INH-NADP

          Argyrou, A, Vetting, MW, and Blanchard, JS

          J Am Chem Soc 2007.

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17636923&dopt=abstract


19.   61374   OI-LS-379; PUBMED-OI-7/23/2007

          Fragment-Based Substrate Activity Screening Method for the Identification of Potent Inhibitors of the Mycobacterium tuberculosis Phosphatase PtpB

          Soellner, MB, Rawls, KA, Grundner, C, Alber, T, and Ellman, JA

          J Am Chem Soc 2007.

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17636914&dopt=abstract

20.   61375   OI-LS-379; PUBMED-OI-7/23/2007

          Rv1106c from Mycobacterium tuberculosis Is a 3beta-Hydroxysteroid Dehydrogenase

          Yang, X, Dubnau, E, Smith, I, and Sampson, NS

          Biochemistry 2007.

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17630785&dopt=abstract

21.   61376   OI-LS-379; PUBMED-OI-7/23/2007

          Phase 2 study of the combination of merimepodib with peginterferon-alpha2b, and ribavirin in nonresponders to previous therapy for chronic hepatitis C

          Marcellin, P, Horsmans, Y, Nevens, F, Grange, JD, Bronowicki, JP, Vetter, D, Purdy, S, Garg, V, Bengtsson, L, McNair, L, and Alam, J

          J Hepatol 2007.

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17629590&dopt=abstract

22.   61377   OI-LS-379; PUBMED-OI-7/23/2007

          Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro

          Strobl, JS, Cassell, M, Mitchell, SM, Reilly, CM, and Lindsay, DS

          J Parasitol 2007.  93(3): 694-700

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17626366&dopt=abstract

23.   61378   OI-LS-379; PUBMED-OI-7/23/2007

          Encapsulation of moxifloxacin within poly(butyl cyanoacrylate) nanoparticles enhances efficacy against intracellular Mycobacterium tuberculosis

          Kisich, KO, Gelperina, S, Higgins, MP, Shipulo, E, Oganesyan, E, and Heifets, L

          Int J Pharm 2007.

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17624699&dopt=abstract


24.   61379   OI-LS-379; PUBMED-OI-7/23/2007

          Lariatins, Novel Anti-mycobacterial Peptides with a Lasso Structure, Produced by Rhodococcus jostii K01-B0171

          Iwatsuki, M, Uchida, R, Takakusagi, Y, Matsumoto, A, Jiang, CL, Takahashi, Y, Arai, M, Kobayashi, S, Matsumoto, M, Inokoshi, J, Tomoda, H, and Omura, S

          J Antibiot (Tokyo) 2007.  60(6): 357-63

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17617692&dopt=abstract

25.   61380   OI-LS-379; PUBMED-OI-7/23/2007

          WHO launches plan to fight drug resistant tuberculosis

          Moszynski, P

          BMJ 2007.  334(7608): 1340-1

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17599995&dopt=abstract