ONLINE DATABASE SEARCH - OI-LS-376-MEMO

 

1.     61036   OI-LS-376; WOS-OI-6/1/2007

          Antiviral and Antimicrobial Profiles of Selected Isoquinoline Alkaloids From Fumaria and Corydalis Species

          Orhan, I. et al.

          Zeitschrift Fur Naturforschung C-a Journal of Biosciences 2007.  62(1-2): 19-26

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245739200004

2.     61037   OI-LS-376; EMBASE-OI-6/11/2007

          Oxadiazole mannich bases: Synthesis and antimycobacterial activity

          Ali, Mohamed Ashraf and Shaharyar, Mohammad

          Bioorganic & Medicinal Chemistry Letters 2007.  17(12): 3314-3316

          View Data on the NIAID Therapeutics Website
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          http://www.sciencedirect.com/science/article/B6TF9-4NF4F18-4/2/4dcb3d555c1a666ffdb8889aa9ab3b45

3.     61038   OI-LS-376; EMBASE-OI-6/11/2007

          Synthesis of Symmetrical C- and Pseudo-symmetrical O-Linked Disaccharide Analogs for Arabinosyltransferase Inhibitory Activity in Mycobacterium tuberculosis

          Pathak, Ashish K, Pathak, Vibha, Riordan, James R, Suling, William J, Gurcha, Sudagar S, Besra, Gurdyal S, and Reynolds, Robert C

          Bioorganic & Medicinal Chemistry Letters 2007.  In Press, Accepted Manuscript: 748

          View Data on the NIAID Therapeutics Website
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          http://www.sciencedirect.com/science/article/B6TF9-4NX2NGR-2/2/5a46bc1bd398300fa41646dafffa5818

4.     61039   OI-LS-376; EMBASE-OI-6/11/2007

          Ligand based virtual screening and biological evaluation of inhibitors of chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv

          Agrawal, Himanshu, Kumar, Ashutosh, Bal, Naresh Chandra, Siddiqi, Mohammad Imran, and Arora, Ashish

          Bioorganic & Medicinal Chemistry Letters 2007.  17(11): 3053-3058

          View Data on the NIAID Therapeutics Website
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          http://www.sciencedirect.com/science/article/B6TF9-4N9P4JN-1/2/9394e0f02abecadfebb9ec89b64ab95c

5.     61040   OI-LS-376; EMBASE-OI-6/11/2007

          Synthesis of 4-phenoxybenzamide adenine dinucleotide as NAD analogue with inhibitory activity against enoyl-ACP reductase (InhA) of Mycobacterium tuberculosis

          Bonnac, Laurent, Gao, Guang-Yao, Chen, Liqiang, Felczak, Krzysztof, Bennett, Eric M, Xu, Hua, Kim, TaeSoo, Liu, Nina, Oh, HyeWon, Tonge, Peter J, and Pankiewicz, Krzysztof W

          Bioorganic & Medicinal Chemistry Letters 2007.  In Press, Corrected Proof:  727

          View Data on the NIAID Therapeutics Website
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          http://www.sciencedirect.com/science/article/B6TF9-4NVT9ST-4/2/9ac22e7762a9507523270f3dfe3b1c92

6.     61041   OI-LS-376; WOS-OI-6/1/2007

          Antimycobacterial Activity From Cyanobacterial Extracts and Phytochemical Screening of Methanol Extract of Hapalosiphon

          Rao, M. et al.

          Pharmaceutical Biology 2007.  45(2): 88-93

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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245677200002

7.     61042   OI-LS-376; EMBASE-OI-6/11/2007

          Crystallographic studies on the binding of isonicotinyl-NAD adduct to wild-type and isoniazid resistant 2-trans-enoyl-ACP (CoA) reductase from Mycobacterium tuberculosis

          Dias, Marcio Vinicius Bertacine, Vasconcelos, Igor Bordin, Prado, Adriane Michele Xavier, Fadel, Valmir, Basso, Luiz Augusto, de Azevedo Jr, Walter Filgueira, and Santos, Diogenes Santiago

          Journal of Structural Biology 2007.  In Press, Uncorrected Proof: 205

          View Data on the NIAID Therapeutics Website
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          http://www.sciencedirect.com/science/article/B6WM5-4NMWRBG-1/2/4bd6bd062be8d6e1517d720d8c5cb4f4

8.     61043   OI-LS-376; EMBASE-OI-6/11/2007

          Newer tetracycline derivatives: Synthesis, anti-HIV, antimycobacterial activities and inhibition of HIV-1 integrase

          Sriram, Dharmarajan, Yogeeswari, Perumal, Senchani, Geetha, and Banerjee, Debjani

          Bioorganic & Medicinal Chemistry Letters 2007.  17(8): 2372-2375

          View Data on the NIAID Therapeutics Website
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          http://www.sciencedirect.com/science/article/B6TF9-4MCMWJ9-1/2/cee6aa86925226a9541d49894620c43a

9.     61044   OI-LS-376; WOS-OI-6/1/2007

          Superinfection Exclusion in Cells Infected With Hepatitis C Virus

          Tscherne, D. et al.

          Journal of Virology 2007.  81(8): 3693-3703

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245692900003

10.   61045   OI-LS-376; WOS-OI-6/1/2007

          New Natural Intergenotypic (2/5) Recombinant of Hepatitis C Virus

          Legrand-Abravanel, F. et al.

          Journal of Virology 2007.  81(8): 4357-4362

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245692900068

11.   61046   OI-LS-376; EMBASE-OI-6/11/2007

          Parameters determining the relative efficacy of hydroxy-naphthoquinone inhibitors of the cytochrome bc1 complex

          Kessl, Jacques J, Moskalev, Nikolai V, Gribble, Gordon W, Nasr, Mohamed, Meshnick, Steven R, and Trumpower, Bernard L

          Biochimica et Biophysica Acta (BBA) - Bioenergetics 2007.  1767(4): 319-326

          View Data on the NIAID Therapeutics Website
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          http://www.sciencedirect.com/science/article/B6T1S-4N4YMMW-1/2/06b9aa82b32b24e76a8037a02efb1a05

12.   61047   OI-LS-376; WOS-OI-6/1/2007

          Antimicrobial Activity of Marine Sponges From Uraba Gulf, Colombian Caribbean Region

          Galeano, E. and Martinez, A.

          Journal De Mycologie Medicale 2007.  17(1): 21-24

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245772400004


13.   61048   OI-LS-376; EMBASE-OI-6/11/2007

          Synthesis, characterization and antimicrobial activity of new aliphatic sulfonamide

          Ozbek, Neslihan, Katircioglu, Hikmet, Karacan, Nurcan, and Baykal, Tulay

          Bioorganic & Medicinal Chemistry 2007.  15(15): 5105-5109

          View Data on the NIAID Therapeutics Website
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          http://www.sciencedirect.com/science/article/B6TF8-4NS2GDD-5/2/ebeffa42266afe22d2de28d486c8af81

14.   61049   OI-LS-376; EMBASE-OI-6/11/2007

          Design, synthesis and molecular docking studies of novel triazole antifungal compounds

          He, Qiu Qin, Li, Ke, Cao, Yong Bing, Dong, Huan Wen, Zhao, Li Hua, Liu, Chao Mei, and Sheng, Chun Quan

          Chinese Chemical Letters 2007.  18(6): 663-666

          View Data on the NIAID Therapeutics Website
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          http://www.sciencedirect.com/science/article/B8G3X-4NVK227-3/2/7b977b09ded38b5bab211645261dcf1b

15.   61050   OI-LS-376; EMBASE-OI-6/11/2007

          Inhibitors of hepatitis C virus NS3.4A protease. Effect of P4 capping groups on inhibitory potency and pharmacokinetics

          Perni, Robert B, Chandorkar, Gurudatt, Cottrell, Kevin M, Gates, Cynthia A, Lin, Chao, Lin, Kai, Luong, Yu-Ping, Maxwell, John P, Murcko, Mark A, Pitlik, Janos, Rao, Govinda, Schairer, Wayne C, Drie, John Van, and Wei, Yunyi

          Bioorganic & Medicinal Chemistry Letters 2007.  17(12): 3406-3411

          View Data on the NIAID Therapeutics Website
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          http://www.sciencedirect.com/science/article/B6TF9-4NDDM03-1/2/7fbe660613e02d9dc3d24884ff9e8aa7

16.   61051   OI-LS-376; WOS-OI-6/1/2007

          Update 2006/2007 - Treatment of Hepatitis

          Anon

          Drugs of the Future 2007.  32(2): 187-190

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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245698900010

17.   61052   OI-LS-376; WOS-OI-6/1/2007

          Drugs Under Development for the Treatment of Hepatitis

          Mealy, N., Lupone, B., and Tell, M.

          Drugs of the Future 2007.  32(2): 191-200

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245698900011

18.   61053   OI-LS-376; WOS-OI-6/1/2007

          Drugs From Academia

          Borman, S.

          Chemical & Engineering News 2007.  85(16): 42-47

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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245737800046


19.   61054   OI-LS-376; WOS-OI-6/1/2007

          Relationship Between Mycobacterium Avium Subspecies Paratuberculosis, Il-1 Alpha, and Traf1 in Primary Bovine Monocyte-Derived Macrophages

          Chiang, S. et al.

          Veterinary Immunology and Immunopathology 2007.  116(3-4 ): 131-144

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245797600002

20.   61055   OI-LS-376; WOS-OI-6/1/2007

          Predicting Hcv Treatment Duration With an Hcv Protease Inhibitor Co-Administered With Peg-Ifn/Rbv by Modeling Both Wild-Type Virus and Low Level Resistant Variant Dynamics

          Khunvichai, A. et al.

          Gastroenterology 2007.  132(4): A740-A741

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245927606139

21.   61056   OI-LS-376; WOS-OI-6/8/2007

          Inhibition of Hepatitis C Virus Replication and Expression by Small Interfering Rna Targeting Host Cellular Genes

          Xue, Q. et al.

          Journal of Hepatology 2007.  46: S151

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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100390

22.   61057   OI-LS-376; WOS-OI-6/8/2007

          Ribavirin Acts as Hepatitis C Virus Mutagen on Nonstructural 5b Quasispecies in Vitro and During Antiviral Therapy

          Hofmann, W. et al.

          Journal of Hepatology 2007.  46: S164

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100429

23.   61058   OI-LS-376; WOS-OI-6/8/2007

          Favorable Cross-Resistance Profile of Two 432 Novel Hepatitis C Virus Inhibitors, Sch-503034 and Hcv-766, and Enhanced Anti-Replicon Activity Mediated by the Combined Use of Both Compounds

          Howe, A. et al.

          Journal of Hepatology 2007.  46: S165

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100431

24.   61059   OI-LS-376; WOS-OI-6/8/2007

          Combinations of 2'-Methylcytidine Analogs With Interferon Alpha-2b Lead to Synergistic Inhibition of Hepatitis C Virus Replication in a Replicon System

          Bassit, L. et al.

          Journal of Hepatology 2007.  46: S217

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100570


25.   61060   OI-LS-376; WOS-OI-6/8/2007

          Ketoprofen Plus Peg-Ifn Alpha-2a and Ribavirin as a Triple Treatment for Genotype 1 (G1) Chronic Hepatitis C (Chc): Results of a Phase Ii Randomized Controlled Trial

          Gramenzi, A. et al.

          Journal of Hepatology 2007.  46: S231

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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100610

26.   61061   OI-LS-376; WOS-OI-6/8/2007

          R1479, a Novel Hepatitis C Polymerase Inhibitor: Lack of Pre-Existing Resistance Mutation Supports the Observed in Vivo High Barrier to Resistance

          Le Pogam, S. et al.

          Journal of Hepatology 2007.  46: S235

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100620

27.   61062   OI-LS-376; WOS-OI-6/8/2007

          Novel Mode of Viral Decline During Telaprevir (Vx-950) and Peg-Ifn Combination Treatment Predicted by a New Combined Intracellular and Cellular Hepatitis C Viral Dynamics Model

          Neumann, A. et al.

          Journal of Hepatology 2007.  46: S236

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100623

28.   61063   OI-LS-376; WOS-OI-6/8/2007

          The Influence of Nucleoside Free Haart on the Treatment of Chronic Hepatitis C With Pegylated Interferon/Ribavirin Combination Treatment

          Rockstroh, J.  et al.

          Journal of Hepatology 2007.  46: S240

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100633

29.   61064   OI-LS-376; WOS-OI-6/8/2007

          Combination of Two Hepatitis C Virus Inhibitors, Sch 503034 and Nm107, Provides Enhanced Antireplicon Activity and Suppresses Emergence of Resistant Replicons

          Ralston, R. et al.

          Journal of Hepatology 2007.  46: S298-S299

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100788

30.   61065   OI-LS-376; WOS-OI-6/8/2007

          Purines Bearing Phenanthroline or Bipyridine Ligands and Their Ru-Ii Complexes in Position 8 as Model Compounds for Electrochemical Dna Labeling - Synthesis, Crystal Structure, Electrochemistry, Quantum Chemical Calculations, Cytostatic and Antiviral Activity

          Vrabel, M. et al.

          European Journal of Inorganic Chemistry 2007.(12): 1752-1769

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246404900016


31.   61066   OI-LS-376; WOS-OI-6/8/2007

          Inhibitory Effects of Various Type Ifn on the Hcv Rna Replication of Hcv Replicon Cells

          Fei, R. et al.

          Journal of Hepatology 2007.  46: S168

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100441

32.   61067   OI-LS-376; WOS-OI-6/8/2007

          Novel 4-Azido-2-Deoxy-Nucleoside Analogs Are Potent Inhibitors of Ns5b-Dependent Hcv Replication

          Smith, D. et al.

          Journal of Hepatology 2007.  46: S190

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100498

33.   61068   OI-LS-376; WOS-OI-6/8/2007

          Ach-806: a Potent Inhibitor of Hcv Replication With a Novel Mechanism of Action

          Huang, M. et al.

          Journal of Hepatology 2007.  46: S221

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100582

34.   61069   OI-LS-376; WOS-OI-6/8/2007

          Inhibition of Hcv Replication by Psi-6130: Mechanism of Biochemical Activation and Inhibition

          Furman, P. et al.

          Journal of Hepatology 2007.  46: S224

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100589

35.   61070   OI-LS-376; WOS-OI-6/8/2007

          Effects of Telapravir (Vx950) in a Liver Biopsy Model of Hcv Infection: Genotype 1 Virions Are Inhibited in Vitro but Other Genotypes Are Less Responsive

          Hibbert, L. and Foster, G.

          Journal of Hepatology 2007.  46: S227

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100598

36.   61071   OI-LS-376; WOS-OI-6/8/2007

          Inhibition of Hcv Replication by Psi-6130: Characterization of Activity in the Hcv Replicon System

          Jiang, W. et al.

          Journal of Hepatology 2007.  46: S228

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100601

37.   61072   OI-LS-376; WOS-OI-6/8/2007

          R1479, a Novel Nucleoside Analog and Potent Inhibitor of Hcv Replication, Does Not Affect Ribavirin-Induced Hemolysis and Erythrocyte Fragility in Vitro

          Jiang, W. et al.

          Journal of Hepatology 2007.  46: S228

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100602


38.   61073   OI-LS-376; WOS-OI-6/8/2007

          Nim811, a Cyclophilin Inhibitor, and Nm107, an Hcv Polymerase Inhibitor, Synergistically Inhibits Hcv Replication and Suppresses the Emergence of Resistance in Vitro

          Lin, K. et al.

          Journal of Hepatology 2007.  46: S230

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100607

39.   61074   OI-LS-376; WOS-OI-6/8/2007

          Characterization of Pharmacokinetic/Pharmacodynamic Parameters for the Novel Hcv Polymerase Inhibitor a-848837

          Molla, A. et al.

          Journal of Hepatology 2007.  46: S234-S235

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100618

40.   61075   OI-LS-376; WOS-OI-6/8/2007

          Short-Term Antiviral Activity and Safety of Ach-806 (Gs-9132), an Ns4a Antagonist, in Hcv Genotype I Infected Individuals

          Pottage, J. et al.

          Journal of Hepatology 2007.  46: S294-S295

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100778

41.   61076   OI-LS-376; WOS-OI-6/8/2007

          The Reduction of Both Cyclophilin B and Hcv-Rna by the Cyclophilin Inhibitor Debio-025 Confirms the Importance of Cyclophilin B for Hcv Replication in Man

          Gallay, R. et al.

          Journal of Hepatology 2007.  46: S296

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100782

42.   61077   OI-LS-376; WOS-OI-6/8/2007

          In Vitro Resistance Selection to the Hcv Nucleoside Polymerase Inhibitor R1479 and to the Protease Inhibitor Vx-950

          Mccown, M. et al.

          Journal of Hepatology 2007.  46: S297-S298

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100785

43.   61078   OI-LS-376; WOS-OI-6/8/2007

          Hcv Antiviral Activity and Resistance Analysis in Chronically Infected Chimpanzees Treated With Ns3/4a Protease and Ns513 Polymerase Inhibitors

          Olsen, D. et al.

          Journal of Hepatology 2007.  46: S298

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246555100786


44.   61079   OI-LS-376; WOS-OI-6/8/2007

          Il-2-Stimulated Natural Killer Cells Inhibit Hcv Replication: a Novel Concept to Prevent the Progression of Hcv Reinfection in Liver-Transplant Recipients Infected With Hcv.

          Ohira, M. et al.

          American Journal of Transplantation 2007.  7: 328

          View Data on the NIAID Therapeutics Website
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          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246370201129

45.   61080   OI-LS-376; PUBMED-OI-6/11/2007

          NAD(+)-dependent DNA ligase (Rv3014c) from Mycobacterium tuberculosis: Novel structure-function relationship and identification of a specific inhibitor

          Srivastava, SK, Dube, D, Kukshal, V, Jha, AK, Hajela, K, and Ramachandran, R

          Proteins 2007.

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17557328&dopt=abstract

46.   61081   OI-LS-376; PUBMED-OI-6/11/2007

          Phenotypic and structural analyses of HCV NS3 protease ARG155 variants: Sensitivity to telaprevir (VX-950) and interferon alpha

          Zhou, Y, Muh, U, Hanzelka, BL, Bartels, DJ, Wei, Y, Rao, BG, Brennan, DL, Tigges, AM, Swenson, L, Kwong, AD, and Lin, C

          J Biol Chem 2007.

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17556358&dopt=abstract

47.   61082   OI-LS-376; PUBMED-OI-6/11/2007

          Synthesis, characterisation and antimicrobial activity of copper(II) and manganese(II) complexes of coumarin-6,7-dioxyacetic acid (cdoaH(2)) and 4-methylcoumarin-6,7-dioxyacetic acid (4-MecdoaH(2)): X-ray crystal structures of [Cu(cdoa)(phen)(2)].8.8H(2)O and [Cu(4-Mecdoa)(phen)(2)].13H(2)O (phen=1,10-phenanthroline)

          Creaven, BS, Egan, DA, Karcz, D, Kavanagh, K, McCann, M, Mahon, M, Noble, A, Thati, B, and Walsh, M

          J Inorg Biochem 2007.

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17555821&dopt=abstract

48.   61083   OI-LS-376; PUBMED-OI-6/11/2007

          Investigating the Metabolic Capabilities of Mycobacterium tuberculosis H37Rv Using the in silico Strain iNJ661 and Proposing Alternative Drug Targets

          Jamshidi, N and Palsson, BO

          BMC Syst Biol 2007.  1(1): 26

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17555602&dopt=abstract


49.   61084   OI-LS-376; PUBMED-OI-6/11/2007

          Design and Synthesis of Classical and Nonclassical 6-Arylthio-2,4-diamino-5-ethylpyrrolo[2,3-d]pyrimidines as Antifolates

          Gangjee, A, Zeng, Y, Talreja, T, McGuire, JJ, Kisliuk, RL, and Queener, SF

          J Med Chem 2007.

          View Data on the NIAID Therapeutics Website
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          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17552508&dopt=abstract

50.   61085   OI-LS-376; PUBMED-OI-6/11/2007

          Hepatitis C virus: Virology, diagnosis and management of antiviral therapy