ONLINE DATABASE SEARCH -
OI-LS-375-MEMO
1.
60923 OI-LS-375;
PUBMED-OI-5/29/2007
Synthesis and biological evaluation of some thiazolyl and thiadiazolyl
derivatives of 1H-pyrazole as anti-inflammatory antimicrobial
agents
Bekhit, AA, Ashour, HM, Abdel, Ghany YS, Bekhit, AE, and Baraka,
A
Eur J Med Chem
2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
2.
60924 OI-LS-375;
SCIFINDER-OI-5/21/2007
Antimicrobial and cytotoxic activity of agelasine and agelasimine
analogs
Vik, Anders, Hedner, Erik, Charnock, Colin, Tangen, Linda W, Samuelsen,
Orjan, Larsson, Rolf, Bohlin, Lars, and Gundersen,
Lise-Lotte
Bioorg. Med. Chem. 2007.
15(12): 4016-4037
View Data on the NIAID Therapeutics Website
HYPERLINK:
3.
60925 OI-LS-375;
PUBMED-OI-5/29/2007
Development and characterization of a recombinant cDNA-based hepatitis C
virus system
Ndjomou, J, Liu, Y, O'malley, J, Ericsson, M, and He,
JJ
Biochem Biophys Res Commun 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
4.
60926 OI-LS-375;
SCIFINDER-OI-5/21/2007
Synergistic antimycobacterial activities of sesquiterpene lactones from
Laurus spp
Luna-Herrera, J, Costa, MC, Gonzalez, HG, Rodrigues, AI, and Castilho,
PC
J. Antimicrob. Chemother. 2007. 59(3): 548-552
View Data on the NIAID Therapeutics Website
HYPERLINK:
5.
60927 OI-LS-375;
PUBMED-OI-5/29/2007
Synthesis and HCV inhibitory properties of 9-deaza- and
7,9-dideaza-7-oxa-2'-C-methyladenosine
Butora, G, Olsen, DB, Carroll, SS, McMasters, DR, Schmitt, C, Leone, JF,
Stahlhut, M, Burlein, C, and Maccoss, M
Bioorg Med Chem 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
6.
60928 OI-LS-375;
PUBMED-OI-5/29/2007
5-Alkynyl Analogs of
Arabinouridine and 2'-Deoxyuridine: Cytostatic Activity against Herpes Simplex
Virus and Varicella-Zoster Thymidine Kinase Gene-Transfected
Cells
Cristofoli, WA, Wiebe, LI, Clercq, ED, Andrei, G, Snoeck, R, Balzarini,
J, and Knaus, EE
J Med Chem 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
7.
60929 OI-LS-375;
PUBMED-OI-5/29/2007
Mechanistic studies of electrophilic protease inhibitors of full length
hepatic C virus (HCV) NS3
Poliakov, A, Sandstrom, A, Akerblom, E, and Danielson,
UH
J
Enzyme Inhib Med Chem 2007.
22(2): 191-9
View Data on the NIAID Therapeutics Website
HYPERLINK:
8.
60930 OI-LS-375;
PUBMED-OI-5/29/2007
Antitubercular activity of novel substituted
4,5-dihydro-1H-1-pyrazolylmethanethiones
Ali, MA and Yar, MS
J Enzyme Inhib Med Chem 2007. 22(2): 183-9
View Data on the NIAID Therapeutics Website
HYPERLINK:
9.
60931 OI-LS-375;
PUBMED-OI-5/29/2007
Immunopathogenesis of hepatitis C virus infection and hepatic fibrosis:
New insights into antifibrotic therapy in chronic hepatitis C
Teixeira, R, Marcos, LA, and Friedman, SL
Hepatol Res
2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
10.
60932 OI-LS-375;
PUBMED-OI-5/29/2007
Lipoprotein lipase mediates hepatitis C virus (HCV) cell entry and
inhibits HCV infection
Andreo, U, Maillard, P, Kalinina, O, Walic, M, Meurs, E, Martinot, M,
Marcellin, P, and Budkowska, A
Cell Microbiol
2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
11.
60933 OI-LS-375;
PUBMED-OI-5/29/2007
Managing multiple and extensively drug-resistant tuberculosis and
HIV
Padayatchi, N and Friedland, G
Expert Opin Pharmacother 2007. 8(8): 1035-7
View Data on the NIAID Therapeutics Website
HYPERLINK:
12.
60934 OI-LS-375;
SCIFINDER-OI-5/21/2007
Unified QSAR approach to antimicrobials. Part 2: Predicting activity
against more than 90 different species in order to halt antibacterial
resistance
Prado-Prado, Francisco J, Gonzalez-Diaz, Humberto, Santana, Lourdes, and
Uriarte, Eugenio
Bioorg. Med. Chem. 2007.
15(2): 897-902
View Data on the NIAID Therapeutics Website
HYPERLINK:
13.
60935 OI-LS-375;
PUBMED-OI-5/29/2007
Discovery of novel dialkyl substituted thiophene inhibitors of HCV by in
silico screening of the NS5B RdRp
Louise-May, S, Yang, W, Nie, X, Liu, D, Deshpande, MS, Phadke, AS, Huang,
M, and Agarwal, A
Bioorg Med Chem Lett 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
14.
60936 OI-LS-375;
PUBMED-OI-5/29/2007
Post-antifungal effects of the antifungal compound
2-(3,4-dimethyl-2,5-dihydro-1H-pyrrol-2-yl)-1-methylethyl pentanoate on
Aspergillus fumigatus
Dabur, R, Mandal, TK, and Sharma, GL
J Med Microbiol 2007.
56(Pt 6): 815-8
View Data on the NIAID Therapeutics Website
HYPERLINK:
15.
60937 OI-LS-375;
PUBMED-OI-5/29/2007
High coverage with HAART is required to substantially reduce the number
of deaths from tuberculosis: system dynamics simulation
Atun, RA, Lebcir, RM, Drobniewski, F, McKee, M, and Coker,
RJ
Int J STD AIDS
2007. 18(4):
267-73
View Data on the NIAID Therapeutics Website
HYPERLINK:
16.
60938 OI-LS-375;
SCIFINDER-OI-5/21/2007
High throughput screening method for antimicrobial
formulations
Novak, John S and Yuan, James TC
PATENT: US
2007042453 ISSUE DATE: 20070222
APPLICATION: 2006-31296 PP:
8pp.
ASSIGNEE:
(USA)
View Data on the NIAID Therapeutics Website
HYPERLINK:
17.
60939 OI-LS-375;
PUBMED-OI-5/29/2007
Antimicrobial evaluation of some arylsulfanylpyrazinecarboxylic Acid
derivatives
Jampilek, J, Dolezal, M, and Buchta, V
Med Chem 2007. 3(3):
277-80
View Data on the NIAID Therapeutics Website
HYPERLINK:
18.
60940 OI-LS-375;
SCIFINDER-OI-5/21/2007
Development and validation of a cell culture based assay for in vitro
assessment of anticryptosporidial compounds
Najdrowski M, Heckeroth A R, Wackwitz C, Gawlowska S, Mackenstedt U,
Kliemt D, and Daugschies A
Parasitol Res 2007.
101(1): 161-7.
View Data on the NIAID Therapeutics Website
HYPERLINK:
19.
60941 OI-LS-375;
PUBMED-OI-5/29/2007
Antimicrobial activity of Diospyros anisandra
Borges-Argaez, R, Canche-Chay, CI, Pena-Rodriguez, LM, Said-Fernandez, S,
and Molina-Salinas, GM
Fitoterapia 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
20.
60942 OI-LS-375;
SCIFINDER-OI-5/21/2007
Antimicrobial activity of a series of thiosemicarbazones and their ZnII
and PdII complexes
Kizilcikli, I, Kurt, YD, Akkurt, B, Genel, AY, Birteksoz, S, Otuk, G, and
Ulkuseven, B
Folia Microbiol. (Prague, Czech Repub.) 2007. 52(1): 15-25
View Data on the NIAID Therapeutics Website
HYPERLINK:
21.
60943 OI-LS-375;
SCIFINDER-OI-5/21/2007
Discovery of micafungin (FK463): a novel antifungal drug derived from a
natural product lead
Fujie, Akihiko
Pure Appl. Chem. 2007.
79(4): 603-614
View Data on the NIAID Therapeutics Website
HYPERLINK:
22.
60944 OI-LS-375;
PUBMED-OI-5/29/2007
Comparison of the effects of three different anti-fungus drugs on Candida
albicans of murine vaginal mucosa
Chen, S, Li, S, Liu, Z, Wu, Y, Tu, Y, and Li, J
J Huazhong Univ Sci Technolog Med Sci 2007. 27(2): 209-12
View Data on the NIAID Therapeutics Website
HYPERLINK:
23.
60945 OI-LS-375;
SCIFINDER-OI-5/21/2007
Study of spectral properties and determination of the biological activity
of a series of 4-[(4-chlorobenzyl)oxy]azobenzenes
Moanta, Anca, Rau, Gabriela, and Radu, Stelian
Rev. Chim. (Bucharest, Rom.) 2007. 58(2): 229-231
View Data on the NIAID Therapeutics Website
HYPERLINK:
24.
60946 OI-LS-375;
PUBMED-OI-5/29/2007
Identification of two Mycobacterium smegmatis lipoproteins exported by a
SecA2-dependent pathway
Gibbons, HS, Wolschendorf, F, Abshire, M, Niederweis, M, and Braunstein,
M
J Bacteriol 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
25.
60947 OI-LS-375;
PUBMED-OI-5/29/2007
Structures of mycobacterium tuberculosis 1-Deoxy-D-Xylulose 5-Phosphate
reductoisomerase provide new insights into catalysis
Henriksson, LM, Unge, T, Carlsson, J, Aqvist, J, Mowbray, SL, and Jones,
TA
J Biol Chem 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
26.
60948 OI-LS-375;
SCIFINDER-OI-5/21/2007
Preparation of pyranodibenzofurans and related compounds with antifungal
and antibacterial activity
Brodin, Priscille Marie Monique, Prado, Soizic, Cole, Stewart T, Koch,
Michel, Tillequin, Fran ois, and Michel, Sylvie
PATENT: EP
1770089 ISSUE DATE:
20070404
APPLICATION: 2005-29904 PP:
39pp.
ASSIGNEE: (Institut Pasteur,
Fr., Centre National de la Recherche Scientifique (CNRS), and Universite Rene
Descartes)
View Data on the NIAID Therapeutics Website
HYPERLINK:
27.
60949 OI-LS-375;
PUBMED-OI-5/29/2007
Rational Design, Synthesis, and Evaluation of Nanomolar Type II
Dehydroquinase Inhibitors
Payne, RJ, Peyrot, F, Kerbarh, O, Abell, AD, and Abell,
C
ChemMedChem 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
28.
60950 OI-LS-375;
SCIFINDER-OI-5/21/2007
Isolation, characterization and antifungal activity of Streptomyces
sampsonii GS 1322
Jain, Praveen Kumar and Jain, PC
Indian J. Exp. Biol. 2007.
45(2): 203-206
View Data on the NIAID Therapeutics Website
HYPERLINK:
29.
60951 OI-LS-375;
SCIFINDER-OI-5/21/2007
Unique applications of novel antifungal drug combinations
Onyewu, Chiatogu and Heitman, Joseph
Anti-Infect. Agents Med. Chem. 2007. 6(1): 3-15
View Data on the NIAID Therapeutics Website
HYPERLINK:
30.
60952 OI-LS-375;
PUBMED-OI-5/29/2007
Risk of acquired drug resistance during short-course directly observed
treatment of tuberculosis in an area with high levels of drug
resistance
Cox, HS, Niemann, S, Ismailov, G, Doshetov, D, Orozco, JD, Blok, L,
Rusch-Gerdes, S, and Kebede, Y
Clin Infect Dis 2007.
44(11): 1421-7
View Data on the NIAID Therapeutics Website
HYPERLINK:
31.
60953 OI-LS-375;
PUBMED-OI-5/29/2007
Fungicidal activities of dihydroferulic Acid alkyl ester
analogues
Beck, JJ, Kim, JH, Campbell, BC, and Chou, SC
J Nat Prod 2007.
70(5): 779-82
View Data on the NIAID Therapeutics Website
HYPERLINK:
32.
60954 OI-LS-375;
SCIFINDER-OI-5/21/2007
Antifungal activity of C3a and C3a-derived peptides against
Candida
Sonesson, Andreas, Ringstad, Lovisa, Andersson Nordahl, Emma, Malmsten,
Martin, Moergelin, Matthias, and Schmidtchen, Artur
Biochim. Biophys. Acta, Biomembr. 2007. 1768(2): 346-353
View Data on the NIAID Therapeutics Website
HYPERLINK:
33.
60955 OI-LS-375;
SCIFINDER-OI-5/21/2007
An antifungal protein from Escherichia coli
Yadav V, Mandhan R, Pasha Q, Pasha S, Katyal A, Chhillar A K, Gupta J,
Dabur R, and Sharma G L
J Med Microbiol 2007.
56(Pt 5): 637-44.
View Data on the NIAID Therapeutics Website
HYPERLINK:
34.
60956 OI-LS-375;
WOS-OI-5/18/2007
Modern analytical approaches to high-throughput drug
discovery
Gomez-Hens, A and Aguilar-Caballos, MP
TRAC-TRENDS IN ANALYTICAL CHEMISTRY 2007. 26(3): 171-182
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245499300014
35.
60957 OI-LS-375;
SCIFINDER-OI-5/21/2007
Antifungal Activity of the Novel Adduct, GX-95, of Silver with
Nanometer-scale Particles to Peptidic Hydrolysates from Collagen
Yaguchi Takashi, Takizawa Kyoko, Taguchi Hideaki, Tanaka Reiko, Kubota
Tadashi, Kubota Yoshiaki, Kubota Masaaki, and Fukushima
Kazutaka
Nippon Ishinkin Gakkai Zasshi 2007. 48(2): 97-100.
View Data on the NIAID Therapeutics Website
HYPERLINK:
36.
60958 OI-LS-375;
SCIFINDER-OI-5/21/2007
Synthesis and antimicrobial activity of symmetrical two-tailed dendritic
tricarboxylato amphiphiles
Sugandhi, Eko W, Falkinham, Joseph O, and Gandour, Richard
D
Bioorg. Med. Chem. 2007.
15(11): 3842-3853
View Data on the NIAID Therapeutics Website
HYPERLINK:
37.
60959 OI-LS-375;
SCIFINDER-OI-5/21/2007
Pleofungins, novel inositol phosphorylceramide synthase inhibitors, from
Phoma sp. SANK 13899. I. Taxonomy, fermentation, isolation, and biological
activities
Yano, Tatsuya, Aoyagi, Azusa, Kozuma, Shiho, Kawamura, Yoko, Tanaka,
Isshin, Suzuki, Yasuhiro, Takamatsu, Yasuyuki, Takatsu, Toshio, and Inukai,
Masatoshi
J. Antibiot. 2007.
60(2): 136-142
View Data on the NIAID Therapeutics Website
HYPERLINK:
38.
60960 OI-LS-375;
SCIFINDER-OI-5/21/2007
Atorvastatin does not exhibit antiviral activity against HCV at
conventional doses: a pilot clinical trial
O'Leary, Jacqueline G, Chan, Jessica L, McMahon, Cory M, and Chung,
Raymond T
Hepatology (Hoboken, NJ, U. S.) 2007. 45(4): 895-898
View Data on the NIAID Therapeutics Website
HYPERLINK:
39.
60961 OI-LS-375;
SCIFINDER-OI-5/21/2007
New cyclic peptide compounds
Neya, Masahiro, Yoshimura, Seiji, Kamijyo, Kazunori, Makino, Takuya,
Yasuda, Minoru, Yamanaka, Toshio, Tsujii, Eisaku, and Yamagishi,
Yukiko
PATENT: WO
2007049803 ISSUE DATE: 20070503
APPLICATION: 2006 PP:
124pp.
ASSIGNEE: (Astellas Pharma
Inc., Japan
View Data on the NIAID Therapeutics Website
HYPERLINK:
40.
60962 OI-LS-375;
SCIFINDER-OI-5/21/2007
Quinazoline derivatives, useful in treating or preventing a flaviviridae
infection, processes for preparing them, and pharmaceutical compositions
containing them
Mathews, Neil, Thomas, Alexander James Floyd, Spencer, Keith Charles,
Dennison, Helena, Barnes, Michael Christopher, Chana, Surinder Singh, Jennens,
Lyn, and Pilkington, Christopher John
PATENT: WO
2007042782 ISSUE DATE: 20070419
APPLICATION: 2006 PP:
35pp.
ASSIGNEE: (Arrow
Therapeutics Limited, UK
View Data on the NIAID Therapeutics Website
HYPERLINK:
41.
60963 OI-LS-375;
SCIFINDER-OI-5/21/2007
2-Heteroarylmethyl-4-(methoxymethyl)-N-acyl pyrrolidine compounds as
antiviral agents, their preparation, pharmaceutical compositions, and use for
treatment of hepatitis C
Haigh, David, Hartley, Charles David, Howes, Peter David, Jarvest,
Richard Lewis, Lazarides, Linos, Nerozzi, Fabrizio, and Smith, Stephen
Allan
PATENT: WO
2007039142 ISSUE DATE: 20070412
APPLICATION: 2006 PP:
55pp.
ASSIGNEE: (Glaxo Group
Limited, UK
View Data on the NIAID Therapeutics Website
HYPERLINK:
42.
60964 OI-LS-375;
SCIFINDER-OI-5/21/2007
2-Heteroarylmethyl-4-pyrazin-2-yl-N-acyl pyrrolidine compounds as
antiviral agents, their preparation, pharmaceutical compositions, and use for
treatment of hepatitis C
Haigh, David, Hartley, Charles David, Howes, Peter David, Lazarides,
Linos, Nerozzi, Fabrizio, and Smith, Stephen Allan
PATENT: WO
2007039143 ISSUE DATE: 20070412
APPLICATION: 2006 PP:
50pp.
ASSIGNEE: (Glaxo Group
Limited, UK
View Data on the NIAID Therapeutics Website
HYPERLINK:
43.
60965 OI-LS-375;
SCIFINDER-OI-5/21/2007
Preparation of 4-carboxypyrazoles as antivirals for treatment of
hepatitis C virus (HCV) infection
Bravi, Gianpaolo, Cheasty, Anne Goretti, Corfield, John Andrew, Grimes,
Richard Martin, Harrison, David, Hartley, Charles David, Howes, Peter David,
Medhurst, Katrina Jane, Meeson, Malcolm Lees, Mordaunt, Jacqueline Elizabeth,
Shah, Pritom, Slater, Martin John, and White, Gemma
Victoria
PATENT: WO
2007039146 ISSUE DATE: 20070412
APPLICATION: 2006 PP:
275pp.
ASSIGNEE: (Smithkline
Beecham Corporation, USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
44.
60966 OI-LS-375;
SCIFINDER-OI-5/21/2007
Preparation of 5,6-dimethylthieno[2,3-d]pyrimidine derivatives as
antiviral agents
Han, Cheol Kyu, Yoon, Jeonghyeok, Kim, Nam-Doo, and Kim,
Jin-Ah
PATENT: WO
2007035010 ISSUE DATE: 20070329
APPLICATION: 2005 PP:
23pp.
ASSIGNEE: (Equispharm Co.,
Ltd S. Korea
View Data on the NIAID Therapeutics Website
HYPERLINK:
45.
60967 OI-LS-375;
SCIFINDER-OI-5/21/2007
Optimization of N-alkyl indole allosteric inhibitors of the HCV NS5B
polymerase enzyme
Pacini, Barbara, Altamura, Sergio, Avolio, Salvatore, Bisbocci, Monica,
DiFilippo, Marcello, DiMarco, Stefania, Gonzalez Paz, Odalys, Laufer, Ralph,
Narjes, Frank, Paonessa, Giacomo, Rowley, Michael, and Harper,
Steven
Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United
States, March 25-29, 2007
2007.: MEDI-084
View Data on the NIAID Therapeutics Website
HYPERLINK:
46.
60968 OI-LS-375;
SCIFINDER-OI-5/21/2007
Benzodiazepines as HCV inhibitors and their preparation, pharmaceutical
compositions and use in the treatment of HCV infection
Bonfanti, Jean-Francois, Doublet, Frederic Marc Maurice, Nyanguile,
Origene, Raboisson, Pierre Jean-Marie Bernard, Rebstock, Anne-Sophie Helene
Marie, and Boutton, Carlo Willy Maurice
PATENT: WO
2007026024 ISSUE DATE: 20070308
APPLICATION: 2006 PP:
196pp.
ASSIGNEE: (Tibotec
Pharmaceuticals Ltd., Ire.
View Data on the NIAID Therapeutics Website
HYPERLINK:
47.
60969 OI-LS-375;
WOS-OI-5/18/2007
Synthesis and antimicrobial activity of
1-(4-aryl-2-thiazolyl)-3-(2-thienyl)-5-aryl-2-pyrazoline
derivatives
Ozdemir, A,
Turan-Zitouni, G, Kaplancikli, ZA, Revial, G, and Guven, K
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2007. 42(3): 403-409
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245475900014
48.
60970 OI-LS-375;
WOS-OI-5/18/2007
Synthesis of pseudopeptides based L-tryptophan as a potential
antimicrobial agent
Lv, J, Yin, L, Liu, TT, and Wang, YM
BIOORGANIC &
MEDICINAL CHEMISTRY LETTERS 2007.
17(6): 1601-1607
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245492400023
49.
60971 OI-LS-375;
WOS-OI-5/18/2007
Activities of DL-alpha-difluoromethylarginine and polyamine analogues
against Cryptosporidium parvum infection in a T-cell receptor alpha-deficient
mouse model
Yarlett, N, Waters, WR, Harp, JA, Wannemuehler, MJ, Morada, M,
Bellcastro, J, Upton, SJ, Marton, LJ, and Frydman, BJ
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 2007. 51(4): 1234-1239
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245416500016
50.
60972 OI-LS-375;
WOS-OI-5/18/2007
Low-oxygen-recovery assay for high-throughput screening of compounds
against nonreplicating Mycobacterium tuberculosis
Cho, SH, Warit, S, Wan, BJ, Hwang, CH, Pauli, GF, and Franzblau,
SG
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 2007. 51(4): 1380-1385
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245416500037
51.
60973 OI-LS-375;
WOS-OI-5/18/2007
Drug therapy of experimental tuberculosis (TB): Improved outcome by
combining SQ109, a new diamine antibiotic, with existing TB
drugs
Nikonenko, BV, Protopopova, M, Sarnala, R, Einck, L, and Nacy,
CA
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY 2007. 51(4): 1563-1565