ONLINE DATABASE SEARCH - OI-LS-374-MEMO

 

1.     60837   OI-LS-374; PUBMED-OI-5/14/2007

          Host Genetics of Mycobacterial Diseases in Mice and Men: Forward Genetic Studies of BCG-osis and Tuberculosis

          Fortin, A, Abel, L, Casanova, JL, and Gros, P

          Annu Rev Genomics Hum Genet 2007.

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17492906&dopt=abstract

2.     60838   OI-LS-374; PUBMED-OI-5/14/2007

          Inhibition of Isolated Mycobacterium tuberculosis Fatty Acid Synthase I by Pyrazinamide Analogs

          Ngo, SC, Zimhony, O, Chung, WJ, Sayahi, H, Jacobs, WR Jr, and Welch, JT

          Antimicrob Agents Chemother 2007.

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17485499&dopt=abstract

3.     60839   OI-LS-374; PUBMED-OI-5/14/2007

          Determination of ethambutol MICs for Mycobacterium tuberculosis and Mycobacterium avium isolates by resazurin microtitre assay

          Jadaun, GP, Agarwal, C, Sharma, H, Ahmed, Z, Upadhyay, P, Faujdar, J, Gupta, AK, Das, R, Gupta, P, Chauhan, DS, Sharma, VD, and Katoch, VM

          J Antimicrob Chemother 2007.

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17483147&dopt=abstract

4.     60840   OI-LS-374; PUBMED-OI-5/14/2007

          Inhibitors of hepatitis C virus NS3.4A protease. Effect of P4 capping groups on inhibitory potency and pharmacokinetics

          Perni, RB, Chandorkar, G, Cottrell, KM, Gates, CA, Lin, C, Lin, K, Luong, YP, Maxwell, JP, Murcko, MA, Pitlik, J, Rao, G, Schairer, WC, Drie, JV, and Wei, Y

          Bioorg Med Chem Lett 2007.

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17482818&dopt=abstract

5.     60841   OI-LS-374; PUBMED-OI-5/14/2007

          Synthesis and antifungal activities of new fluconazole analogues with azaheterocycle moiety

          Lebouvier, N, Pagniez, F, Duflos, M, Le, Pape P, Na, YM, Le, Baut G, and Le, Borgne M

          Bioorg Med Chem Lett 2007.

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17482460&dopt=abstract


6.     60842   OI-LS-374; PUBMED-OI-5/14/2007

          Structure, function and drug targeting in Mycobacterium tuberculosis cytochrome P450 systems

          McLean, KJ, Dunford, AJ, Neeli, R, Driscoll, MD, and Munro, AW

          Arch Biochem Biophys 2007.

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17482138&dopt=abstract

7.     60843   OI-LS-374; PUBMED-OI-5/14/2007

          Inosine monophosphate dehydrogenase (IMPDH) as a target in drug discovery

          Shu, Q and Nair, V

          Med Res Rev 2007.

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17480004&dopt=abstract

8.     60844   OI-LS-374; PUBMED-OI-5/14/2007

          Carbonic anhydrases as targets for medicinal chemistry

          Supuran, CT and Scozzafava, A

          Bioorg Med Chem 2007.

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17475500&dopt=abstract

9.     60845   OI-LS-374; PUBMED-OI-5/14/2007

          Treatment of hepatitis C virus infection

          Weigand, K, Stremmel, W, and Encke, J

          World J Gastroenterol 2007.  13(13): 1897-905

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17461488&dopt=abstract

10.   60846   OI-LS-374; PUBMED-OI-5/14/2007

          Biochemical Mechanism of Hepatitis C Virus Inhibition by the Broad-Spectrum Antiviral Arbidol

          Pecheur, EI, Lavillette, D, Alcaras, F, Molle, J, Boriskin, YS, Roberts, M, Cosset, FL, and Polyak, SJ

          Biochemistry 2007.

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17455911&dopt=abstract

11.   60847   OI-LS-374; PUBMED-OI-5/14/2007

          XDR-TB--danger ahead

          Singh, MM

          Indian J Tuberc 2007.  54(1): 1-2

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17455416&dopt=abstract

12.   60848   OI-LS-374; EMBASE-OI-5/14/2007

          Entry of hepatitis C virus and human immunodeficiency virus is selectively inhibited by carbohydrate-binding agents but not by polyanions

          Bertaux, Claire, Daelemans, Dirk, Meertens, Laurent, Cormier, Emmanuel G, Reinus, John F, Peumans, Willy J, Van Damme, Els JM, Igarashi, Yasuhiro, Oki, Toshikazu, Schols, Dominique, Dragic, Tatjana, and Balzarini, Jan

          Virology 2007.  In Press, Corrected Proof: 2064

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.sciencedirect.com/science/article/B6WXR-4NPHMH0-4/2/d0018d1e2ac221673bebf716f0d2d288

13.   60849   OI-LS-374; PUBMED-OI-5/14/2007

          Lumazine synthase from Candida albicans as an anti-fungal target enzyme: Structural and biochemical basis for drug design

          Morgunova, E, Saller, S, Haase, I, Cushman, M, Bacher, A, Fischer, M, and Ladenstein, R

          J Biol Chem 2007.

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17446177&dopt=abstract

14.   60850   OI-LS-374; PUBMED-OI-5/14/2007

          Aptamer from whole-bacterium SELEX as new therapeutic reagent against virulent Mycobacterium tuberculosis

          Chen, F, Zhou, J, Luo, F, Mohammed, AB, and Zhang, XL

          Biochem Biophys Res Commun 2007.  357(3): 743-8

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17442275&dopt=abstract

15.   60851   OI-LS-374; PUBMED-OI-5/14/2007

          Tuberculosis: still a concern for all countries in Europe

          Falzon, D and Belghiti, F

          Euro Surveill 2007.  12(3): E070322.1

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17439790&dopt=abstract

16.   60852   OI-LS-374; EMBASE-OI-5/14/2007

          Inhibition of T-Cell Inflammatory Cytokines, Hepatocyte NF-[kappa]B Signaling, and HCV Infection by Standardized Silymarin

          Polyak, Stephen J, Morishima, Chihiro, Shuhart, Margaret C, Wang, Chia C, Liu, Yanze, and Lee, David Y-W

          Gastroenterology 2007.  132(5): 1925-1936

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.sciencedirect.com/science/article/B6WFX-4N3P02C-3/2/a1de6f3eeb52d0eb78d285656ee51cd6


17.   60853   OI-LS-374; EMBASE-OI-5/14/2007

          The Hepatitis C Virus Life Cycle as a Target for New Antiviral Therapies

          Pawlotsky, Jean-Michel, Chevaliez, Stephane, and McHutchison, John G

          Gastroenterology 2007.  132(5): 1979-1998

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.sciencedirect.com/science/article/B6WFX-4NN7Y57-S/2/3e87f421f22aaaade7493f318723a735

18.   60854   OI-LS-374; EMBASE-OI-5/14/2007

          A method for in vitro assembly of hepatitis C virus core protein and for screening of inhibitors

          Fromentin, Remi, Majeau, Nathalie, Gagne, Marie-Eve Laliberte, Boivin, Annie, Duvignaud, Jean-Baptiste, and Leclerc, Denis

          Analytical Biochemistry 2007.  In Press, Corrected Proof: 375

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.sciencedirect.com/science/article/B6W9V-4ND60M3-5/2/dff5cbfe4f10056fe348583faa40f9d2

19.   60855   OI-LS-374; EMBASE-OI-5/14/2007

          Phosphorylation of hepatitis C virus NS5A nonstructural protein: A new paradigm for phosphorylation-dependent viral RNA replication?

          Huang, Ying, Staschke, Kirk, De Francesco, Raffaele, and Tan, Seng-Lai

          Virology 2007.  In Press, Corrected Proof: 375

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.sciencedirect.com/science/article/B6WXR-4ND70B3-1/2/9bbac33ce873b9da3c04ff8a5a649577

20.   60856   OI-LS-374; EMBASE-OI-5/14/2007

          Synthesis, stereochemistry and antimicrobial evaluation of t(3)-benzyl-r(2),c(6)-diarylpiperidin-4-one and its derivatives

          Jayabharathi, J, Manimekalai, A, Consalata Vani, T, and Padmavathy, M

          European Journal of Medicinal Chemistry 2007.  42(5): 593-605

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.sciencedirect.com/science/article/B6VKY-4MFSNYJ-3/2/6a0854d9176c7b1c431b14c7255a3a9e

21.   60857   OI-LS-374; EMBASE-OI-5/14/2007

          7-Oxo-4,7-dihydrothieno[3,2-b]pyridine-6-carboxamides: Synthesis and Biological Activity of a New Class of Highly Potent Inhibitors of Human Cytomegalovirus DNA Polymerase

          Larsen, Scott D, Zhang, Zhijun, DiPaolo, Brian A, Manninen, Peter R, Rohrer, Douglas C, Hageman, Michael J, Hopkins, Todd A, Knechtel, Mary L, Oien, Nancee L, Rush, Bob D, Schwende, Francis J, Stefanski, Kevin J, Wieber, Janet L, Wilkinson, Karen F, Zamora, Kathyrn M, Wathen, Michael W, and Brideau, Roger J

          Bioorganic & Medicinal Chemistry Letters 2007.  In Press, Accepted Manuscript: 927

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://www.sciencedirect.com/science/article/B6TF9-4NP980V-5/2/0533de43ab76b946aeccd13baca0eb37


22.   60858   OI-LS-374; WOS-OI-5/4/2007

          Synthesis, critical micelle concentrations, and antimycobacterial properties of homologous, dendritic amphiphiles. Probing intrinsic activity and the "cutoff" effect

          Sugandhi, EW, Macri, RV, Williams, AA, Kite, BL, Slebodnick, C, Falkinham, JO, Esker, AR, and Gandour, RD

          JOURNAL OF MEDICINAL CHEMISTRY 2007.  50(7): 1645-1650

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245259000023

23.   60859   OI-LS-374; WOS-OI-5/4/2007

          The manzamines as an example of the unique structural classes available for the discovery and optimization of infectious disease controls based on marine natural products

          Hamann, MT

          CURRENT PHARMACEUTICAL DESIGN 2007.  13(6): 653-660

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245201200008

24.   60860   OI-LS-374; WOS-OI-5/4/2007

          P56 LCK inhibitor identification by pharmacophore modelling and molecular docking

          Bharatham, N, Bharatham, K, and Lee, KW

          BULLETIN OF THE KOREAN CHEMICAL SOCIETY 2007.  28(2): 200-206

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245197800010

25.   60861   OI-LS-374; WOS-OI-5/11/2007

          Dimethyldithioimidocarbonates-mediated heterocyclizations: Synthesis of imidazolidines and benzheterocycles as potent antitubercular agents

          Hegde, VS, Kolavi, GD, Lamani, RS, and Khazi, IAM

          PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS 2007.  182(4): 911-920

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245316700020

26.   60862   OI-LS-374; WOS-OI-5/11/2007

          Combinatorial RNAi: A winning strategy for the race against evolving targets?

          Grimm, D and Kay, MA

          MOLECULAR THERAPY 2007.  15(5): 878-888

          View Data on the NIAID Therapeutics Website
HYPERLINK:

          http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000245999500006