ONLINE DATABASE SEARCH - OI-LS-370-MEMO

1. 60442 OI-LS-370; EMBASE-OI-3/19/2007

Evaluation of N-(phenylmethyl)-4-[5-(phenylmethyl)-4,5,6,7-tetrahydro-1 H - imidazo[4,5-c]pyridin-4-yl]benzamide inhibitors of Mycobacterium tuberculosis growth

Wall, Michael D, Oshin, Michael, Chung, Gavin AC, Parkhouse, Tony, Gore, Andrea, Herreros, Esperanza, Cox, Brian, Duncan, Ken, Evans, Brian, Everett, Martin, and Mendoza, Alfonso

Bioorganic & Medicinal Chemistry Letters 2007. In Press, Accepted Manuscript: 734

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http://www.sciencedirect.com/science/article/B6TF9-4N5TN59-D/2/0c4039958ca7ea80fb15acb559ab8a28

2. 60443 OI-LS-370; PUBMED-OI-3/19/2007

Hepatitis C virus infection and hepatotoxicity during antituberculosis chemotherapy

Kwon, YS, Koh, WJ, Suh, GY, Chung, MP, Kim, H, and Kwon, OJ

Chest 2007. 131(3): 803-8

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17356096&dopt=abstract

3. 60444 OI-LS-370; PUBMED-OI-3/19/2007

Antiviral profiles of novel iminocyclitol compounds against bovine viral diarrhea virus, West Nile virus, dengue virus and hepatitis B virus

Gu, B, Mason, P, Wang, L, Norton, P, Bourne, N, Moriarty, R, Mehta, A, Despande, M, Shah, R, and Block, T

Antivir Chem Chemother 2007. 18(1): 49-59

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17354651&dopt=abstract

4. 60445 OI-LS-370; EMBASE-OI-3/19/2007

Synthesis, structural activity relationship and anti-tubercular activity of novel pyrazoline derivatives

Ali, Mohamed Ashraf, Shaharyar, Mohammad, and Siddiqui, Anees Ahamed

European Journal of Medicinal Chemistry 2007. 42(2): 268-275

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http://www.sciencedirect.com/science/article/B6VKY-4M04HTT-1/2/e60f9cd203b48031c2843c3b620dc484

5. 60446 OI-LS-370; PUBMED-OI-3/19/2007

The Role of Homoserine Transacetylase as a New Target for Antifungal Agents

Nazi, I, Scott, A, Sham, A, Rossi, L, Williamson, PR, Kronstad, JW, and Wright, GD

Antimicrob Agents Chemother 2007.

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17353245&dopt=abstract

6. 60447 OI-LS-370; PUBMED-OI-3/19/2007

Enoyl reductases as targets for the development of anti-tubercular and anti-malarial agents

Oliveira, JS, Vasconcelos, IB, Moreira, IS, Santos, DS, and Basso, LA

Curr Drug Targets 2007. 8(3): 399-411

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17348833&dopt=abstract

7. 60448 OI-LS-370; PUBMED-OI-3/19/2007

Totarol Inhibits Bacterial Cytokinesis by Perturbing the Assembly Dynamics of FtsZ

Jaiswal, R, Beuria, TK, Mohan, R, Mahajan, SK, and Panda, D

Biochemistry 2007.

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17348691&dopt=abstract

8. 60449 OI-LS-370; PUBMED-OI-3/19/2007

Antimycobacterial activity of bacteriocins and their complexes with liposomes

Sosunov, V, Mischenko, V, Eruslanov, B, Svetoch, E, Shakina, Y, Stern, N, Majorov, K, Sorokoumova, G, Selishcheva, A, and Apt, A

J Antimicrob Chemother 2007.

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17347179&dopt=abstract

9. 60450 OI-LS-370; PUBMED-OI-3/19/2007

FtsZ: a novel target for tuberculosis drug discovery

Huang, Q, Tonge, PJ, Slayden, RA, Kirikae, T, and Ojima, I

Curr Top Med Chem 2007. 7(5): 527-43

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17346197&dopt=abstract

10. 60451 OI-LS-370; PUBMED-OI-3/19/2007

Screening for novel antituberculosis agents that are effective against multidrug resistant tuberculosis

Matsumoto, M, Hashizume, H, Tsubouchi, H, Sasaki, H, Itotani, M, Kuroda, H, Tomishige, T, Kawasaki, M, and Komatsu, M

Curr Top Med Chem 2007. 7(5): 499-507

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17346195&dopt=abstract

11. 60452 OI-LS-370; PUBMED-OI-3/19/2007

Purine metabolism in Mycobacterium tuberculosis as a target for drug development

Parker, WB and Long, MC

Curr Pharm Des 2007. 13(6): 599-608

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17346177&dopt=abstract

12. 60453 OI-LS-370; PUBMED-OI-3/19/2007

Galactose-derived phosphonate analogues as potential inhibitors of phosphatidylinositol biosynthesis in mycobacteria

Dinev, Z, Gannon, CT, Egan, C, Watt, JA, McConville, MJ, and Williams, SJ

Org Biomol Chem 2007. 5(6): 952-9

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17340011&dopt=abstract

13. 60454 OI-LS-370; PUBMED-OI-3/19/2007

Synthesis and in vitro antimicrobial activity of new 2-[p-substituted-benzyl]-5-[substituted-carbonylamino]benzoxazoles

Tekiner-Gulbas, B, Temiz-Arpaci, O, Yildiz, I, and Altanlar, N

Eur J Med Chem 2007.

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17337097&dopt=abstract

14. 60455 OI-LS-370; PUBMED-OI-3/19/2007

Synthesis of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase (CYP51)

Sun, QY, Xu, JM, Cao, YB, Zhang, WN, Wu, QY, Zhang, DZ, Zhang, J, Zhao, HQ, and Jiang, YY

Eur J Med Chem 2007.

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17335940&dopt=abstract

15. 60456 OI-LS-370; PUBMED-OI-3/19/2007

Protein Flexibility and Species Specificity in Structure-Based Drug Discovery: Dihydrofolate Reductase as a Test System

Bowman, AL, Lerner, MG, and Carlson, HA

J Am Chem Soc 2007.

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17335207&dopt=abstract

16. 60457 OI-LS-370; PUBMED-OI-3/19/2007

Novel medicine to prevent fungal infections

Anon

FDA Consum 2006. 40(6): 2

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http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17333551&dopt=abstract

17. 60458 OI-LS-370; EMBASE-OI-3/19/2007

QSAR analysis for heterocyclic antifungals

Duchowicz, Pablo R, Vitale, Martin G, Castro, Eduardo A, Fernandez, Michael, and Caballero, Julio

Bioorganic & Medicinal Chemistry 2007. In Press, Corrected Proof: 46

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http://www.sciencedirect.com/science/article/B6TF8-4MWPSGJ-4/2/3910bc14a5ba6698b087efc2d44c5169

18. 60459 OI-LS-370; EMBASE-OI-3/19/2007

Design, synthesis of novel antifungal triazole derivatives with high activities against Aspergillus fumigatus

He, Qiu Qin, Liu, Chao Mei, Li, Ke, and Cao, Yong Bing

Chinese Chemical Letters 2007. In Press, Corrected Proof: 1607

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http://www.sciencedirect.com/science/article/B8G3X-4N7Y8HM-N/2/47bfd87b0cd384c1468db435633ec554

19. 60460 OI-LS-370; EMBASE-OI-3/19/2007

Further Studies on Hepatitis C Virus NS5B RNA-Dependent RNA Polymerase Inhibitors toward Improved Replicon Cell Activities: Benzimidazole and Structurally Related Compounds Bearing 2-Morpholinophenyl Moiety

Hirashima, Shintaro, Oka, Takahiro, Ikegashira, Kazutaka, Noji, Satoru, Yamanaka, Hiroshi, Hara, Yoshinori, Goto, Hiroyuki, Mizojiri, Ryo, Niwa, Yasushi, Noguchi, Toru, Ando, Izuru, Ikeda, Satoru, and Hashimoto, Hiromasa

Bioorganic & Medicinal Chemistry Letters 2007. In Press, Accepted Manuscript

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http://www.sciencedirect.com/science/article/B6TF9-4N85B0V-2/2/614bd11b02165b3186373cb3d3db174a

20. 60461 OI-LS-370; EMBASE-OI-3/19/2007

Development of Hepatitis C Virus (HCV) Chimeric Replicons for Identifying Broad Spectrum NS3 Protease Inhibitors

Binder, Joseph, Tetangco, Selwyna, Wick, Megan, Maegley, Karen, Lingardo, Laura, Patick, Amy, and Smith, George

Antiviral Research 2007. In Press, Uncorrected Proof

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http://www.sciencedirect.com/science/article/B6T2H-4N3X611-11/2/d4581f8106157e70c64539a99dd519cd

21. 60462 OI-LS-370; EMBASE-OI-3/19/2007

Development of Intergenotypic Chimeric Replicons for Broad-spectrum Antiviral Activity Characterization of Hepatitis C Virus Polymerase Inhibitors

Herlihy, Koleen

Antiviral Research 2007. In Press, Uncorrected Proof

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http://www.sciencedirect.com/science/article/B6T2H-4N3X611-2T/2/dcfb274dc58c784759abb8d22c124238

22. 60463 OI-LS-370; EMBASE-OI-3/19/2007

17-AAG, an Hsp90 Inhibitor, Suppress Hepatitis C Virus (HCV) Replication

Ujino, Saneyuki, Shimotohno, Kunitada, and Takaku, Hiroshi

Antiviral Research 2007. In Press, Uncorrected Proof

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http://www.sciencedirect.com/science/article/B6T2H-4N3X611-33/2/4d001222c555b050d592b8cc0b7d6dde

23. 60464 OI-LS-370; WOS-OI-3/12/2007

Synergistic fungicidal activities of amphotericin B and N-methyl-N ''-dodecylguanidine: A constituent of polyol macrolide antibiotic niphimycin

Ogita, A, Matsumoto, K, Fujita, K, Usuki, Y, Hatanaka, Y, and Tanaka, T

JOURNAL OF ANTIBIOTICS 2007. 60(1): 27-35, 9

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http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000244134600004

24. 60465 OI-LS-370; WOS-OI-3/12/2007

Intranasal IFN gamma and anti alpha-crystallin IgA inhibit Mycobacterium tuberculosis lung infection in mice

Reljic, R, Williams, A, Clark, S, Marsh, P, and Ivanyi, J

IMMUNOLOGY 2007. 120: 43-1

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http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000244080000166

25. 60466 OI-LS-370; WOS-OI-3/12/2007

Inhibitory effects of oligodeoxynucleotides on hepatitis C viral translation

Li, XY and Wimmer, E

HEPATOLOGY 2006. 44(4): 347A-348A, 2

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http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362300422

26. 60467 OI-LS-370; WOS-OI-3/12/2007

Robust suppression of viral replication by a nucleoside polymerase inhibitor in chimpanzees infected with hepatitis C virus

Carroll, SS, Davies, ME, Handt, L, Koeplinger, K, Zhang, R, Ludmerer, S, MacCoss, M, Hazuda, D, and Olsen, D

HEPATOLOGY 2006. 44(4): 535A-1

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http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302029

27. 60468 OI-LS-370; WOS-OI-3/12/2007

Viral dynamics study with HCVNS3-4A protease inhibitor MP-424/VX-950 in human-chimeric liver mouse model for hepatitis C virus infection

Kamiya, N, Iwao, E, Hiraga, N, Imamura, M, Takahashi, S, and Chayama, K

HEPATOLOGY 2006. 44(4): 535A-1

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http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302030

28. 60469 OI-LS-370; WOS-OI-3/12/2007

Glucosidase inhibitors induce HCV glycoproteins misfolding, impair viral assembly and release, and reduce the infectivity of residually secreted HCV particles

Chapel, C, Garcia, C, Bartosch, B, Roingeard, P, Zitzmann, N, Cosset, FL, Dubuisson, J, Dwek, R, Trepo, C, Zoulim, F, and Durantel, D

HEPATOLOGY 2006. 44(4): 198A-1

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http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362300027

29. 60470 OI-LS-370; WOS-OI-3/12/2007

Effect of an IMPDH inhibitor, merimepodib (MMPD), assessed alone and in combination with ribavirin, on HCV replication: Implications regarding ribavirin's mechanism of action

Hezode, C, Bouvier-Alias, M, Costentin, C, Medkour, F, Franc-Poole, E, Aalyson, M, Alam, J, Dhumeaux, D, and Pawlotsky, JM

HEPATOLOGY 2006. 44(4): 615A-1

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http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302237

30. 60471 OI-LS-370; WOS-OI-3/12/2007

Inhibition of HCV RNA synthesis by the expression of RNA structural mimicry

Smolic, R, Smith, RM, Volarevic, M, Andorfer, JH, Wu, CH, and Wu, GY

HEPATOLOGY 2006. 44(4): 696A-1

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http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302452

31. 60472 OI-LS-370; WOS-OI-3/12/2007

Interim results from a randomized, double-blind, placebo-controlled phase 1b study in subjects with chronic HCV after treatment with GI-5005, a yeast-based HCV immunotherapy targeting NS3 and core proteins

Everson, GT, Tong, MJ, Jacobson, IM, Jensen, DM, Haller, AA, Lauer, GM, Parker, J, Ferraro, J, Cruickshank, SE, Duke, RC, Apelian, D, Rodell, TC, and Schiff, ER

HEPATOLOGY 2006. 44(4): 697A-698A, 2

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http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302456

32. 60473 OI-LS-370; WOS-OI-3/18/2007

Domain analysis of fatty acid synthase protein (NP_217040) from Mycobacterium tuberculosis H37Rv - A bioinformatics study

Ramesh, KV, Wagle, K, and Deshmukh, S

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS 2007. 24(4): 393-412, 20

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http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000244281900008

33. 60474 OI-LS-370; WOS-OI-3/18/2007

Discovery of new drug candidates using structural chemoproteomics

Ro, S