ONLINE DATABASE SEARCH -
HIV-LS-379-MEMO
1.
61304 HIV-LS-379;
SCIFINDER-HIV-7/16/2007
Topochemical models for anti-HIV activity of
1-alkoxy-5-alkyl-6-(arylthio)uracils
Bajaj, S and Madan, AK
Chem. Pap. 2007.
61(2): 127-132
View Data on the NIAID Therapeutics Website
HYPERLINK:
2.
61305 HIV-LS-379;
SCIFINDER-HIV-7/16/2007
N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)]thiourea (HI-443), a
rationally designed non-nucleoside reverse transcriptase inhibitor compound with
potent anti-HIV activity
Uckun, Fatih M, Qazi, Sanjive, and Venkatachalam,
Taracad
Arzneim. Forsch. 2007.
57(5): 278-285
View Data on the NIAID Therapeutics Website
HYPERLINK:
3.
61306 HIV-LS-379;
SCIFINDER-HIV-7/16/2007
Synergistic inhibition of protease-inhibitor-resistant HIV type 1 by
saquinavir in combination with atazanavir or lopinavir
Dam, Elisabeth, Lebel-Binay, Sophie, Rochas, Severine, Thibaut, Laurent,
Faudon, Jean-Louis, Thomas, Claire-Marie, Essioux, Laurent, Hill, Andrew,
Schutz, Malte, and Clavel, Francois
Antiviral Ther. 2007.
12(3): 371-380
View Data on the NIAID Therapeutics Website
HYPERLINK:
4.
61307 HIV-LS-379;
SCIFINDER-HIV-7/16/2007
Maribavir: 1263W94, benzimidavir, GW 1263, GW 1263W94,
VP41263
Anon
Drugs R&D 2007.
8(3): 188-192
View Data on the NIAID Therapeutics Website
HYPERLINK:
5.
61308 HIV-LS-379;
SCIFINDER-HIV-7/16/2007
Human immunodeficiency virus type 1 variants resistant to first- and
second-version fusion inhibitors and cytopathic in ex vivo human lymphoid
tissue
Chinnadurai, Raghavan, Rajan, Devi, Muench, Jan, and Kirchhoff,
Frank
J. Virol. 2007.
81(12): 6563-6572
View Data on the NIAID Therapeutics Website
HYPERLINK:
6.
61309 HIV-LS-379;
SCIFINDER-HIV-7/16/2007
Preparation of pyrimidine derivatives as HIV integrase
inhibitors
Naidu, Narasimhulu B, Ueda, Yasutsugu, and Connolly, Timothy
P
PATENT: WO 2007064619 ISSUE DATE: 20070607
APPLICATION: 2006 PP:
129pp.
ASSIGNEE: (Bristol-Myers
Squibb Company, USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
7.
61310 HIV-LS-379;
SCIFINDER-HIV-7/16/2007
Anti-viral griffithsin proteins and methods of inhibiting viral
infections
O'Keefe, Barry R, Mori, Toshiyuki, and McMahon, James
B
PATENT: WO
2007064844 ISSUE DATE: 20070607
APPLICATION: 2006 PP:
79pp.
ASSIGNEE: (Government of the
United States of America, Represented by the Secretary Department of Health and
Human Services USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
8.
61311 HIV-LS-379;
WOS-HIV-7/13/2007
Synthesis of Novel Pett Analogues: 3,4-Dimethoxy Phenyl Ethyl
1,3,5-Triazinyl Thiourea Derivatives and Their Antibacterial and Anti-Hiv
Studies
Patel, R. et al.
Journal of the Brazilian Chemical Society 2007. 18(2): 312-321
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246443800010
9.
61312 HIV-LS-379;
WOS-HIV-7/13/2007
C34, a Membrane Fusion Inhibitor, Blocks Hiv Infection of Langerhans
Cells and Viral Transmission to T Cells
Sugaya, M. et al.
Journal of Investigative Dermatology 2007. 127(6): 1436-1443
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246618300024
10.
61313 HIV-LS-379;
SCIFINDER-HIV-7/16/2007
Preparation of acyclic nucleotides as antiviral agents
Zhao, Mingyan and Zhong, Suling
PATENT: CN
1966514 ISSUE DATE:
20070523
APPLICATION: 1011-7768 PP:
15pp.
ASSIGNEE: (Beijing Meibeita
Pharmaceutical Co., Ltd. Peop. Rep. China
View Data on the NIAID Therapeutics Website
HYPERLINK:
11.
61314 HIV-LS-379;
SCIFINDER-HIV-7/16/2007
Synthesis and in vitro antiviral studies of bis (pivaloyloxymethyl) ester
derivative of 9-{((phosphonomethyl) aziridin-1-yl)methyl}adenine (PMAMA) and
analogues
Sheikha, Ghassan MAbu, Bkhaitan, Majdi M, Al-Hourani, Rami A, Qaisi, Ali
M, Loddo, Roberta, and La Colla, Paolo
Saudi Pharm. J. 2007.
15(1): 16-22
View Data on the NIAID Therapeutics Website
HYPERLINK:
12.
61315 HIV-LS-379;
SCIFINDER-HIV-7/16/2007
Inhibition of HIV-1 multiplication by a modified U7 snRNA inducing Tat
and Rev exon skipping
Asparuhova, Maria B, Marti, Gabriela, Liu, Songkai, Serhan, Fatima,
Trono, Didier, and Schumperli, Daniel
J. Gene Med. 2007.
9(5): 323-334
View Data on the NIAID Therapeutics Website
HYPERLINK:
13.
61316 HIV-LS-379;
SCIFINDER-HIV-7/16/2007
Pharmaceutical combination of nucleoside and nucleotide reverse
transcriptase inhibitors
Lulla, Amar and Malhotra, Geena
PATENT: WO
2007068934 ISSUE DATE: 20070621
APPLICATION: 2006 PP:
25pp.
ASSIGNEE: (Cipla Limited,
India and Curtis, Philip Anthony
View Data on the NIAID Therapeutics Website
HYPERLINK:
14.
61317 HIV-LS-379;
WOS-HIV-7/13/2007
Preclinical Safety Assessments of Uc781 Anti-Human Immunodeficiency Virus
Topical Microbicide Formulations
Patton, D. et al.
Antimicrobial Agents and Chemotherapy 2007. 51(5): 1608-1615
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246541500003
15.
61318 HIV-LS-379;
WOS-HIV-7/13/2007
Preclinical Testing of Candidate Topical Microbicides for Anti-Human
Immunodeficiency Virus Type 1 Activity and Tissue Toxicity in a Human Cervical
Explant Culture
Cummins, J. et al.
Antimicrobial Agents and
Chemotherapy 2007. 51(5):
1770-1779
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246541500026
16.
61319 HIV-LS-379;
SCIFINDER-HIV-7/16/2007
HIV gp41 C-terminal Heptad Repeat Contains Multifunctional Domains:
relation to mechanisms of action of anti-HIV peptides
Liu, Shuwen, Jing, Weiguo, Cheung, Byron, Lu, Hong, Sun, Jane, Yan,
Xuxia, Niu, Jinkui, Farmar, James, Wu, Shuguang, and Jiang,
Shibo
J. Biol. Chem.
2007. 282(13):
9612-9620
View Data on the NIAID Therapeutics Website
HYPERLINK:
17.
61320 HIV-LS-379;
SCIFINDER-HIV-7/16/2007
Glucuronidation of anti-HIV drug candidate bevirimat: identification of
human UDP-glucuronosyltransferases and species differences
Wen, Zhiming, Martin, David E, Bullock, Peter, Lee, Kuo-Hsiung, and
Smith, Philip C
Drug Metab. Dispos. 2007.
35(3): 440-448
View Data on the NIAID Therapeutics Website
HYPERLINK:
18.
61321 HIV-LS-379;
WOS-HIV-7/20/2007
Enfuvirtide: the First Step for a New Strategy of Antiretroviral
Therapy.
Bottaro, E.
Medicina-Buenos Aires 2007.
67(2): 195-205
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246627900016
19.
61322 HIV-LS-379;
WOS-HIV-7/20/2007
Nucleoside Reverse Transcriptase Inhibitors and Human Immunodeficiency
Virus Proteins Cause Axonal Injury in Human Dorsal Root Ganglia
Cultures
Robinson, B., Li, Z., and Nath, A.
Journal of Neurovirology 2007. 13(2): 160-167
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246763800008
20.
61323 HIV-LS-379;
WOS-HIV-7/20/2007
A Dimeric Lactone From Ardisia Japonica With Inhibitory Activity for
Hiv-1 and Hiv-2 Ribonuclease H
Dat, N. et al.
Journal of Natural Products 2007. 70(5): 839-841
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246764300022
21.
61324 HIV-LS-379;
WOS-HIV-7/20/2007
Development of a Novel Fusion Inhibitor Against T-20-Resistant
Hiv-1
Qishi, S. et al.
Biopolymers 2007.
88(4): 524
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000247425900046
22.
61325 HIV-LS-379;
WOS-HIV-7/20/2007
Synthesis of Biotinyl-Tn-14403, Anti-Hiv Peptide Amide
Nedev, H. and Saragovi, H.
Biopolymers 2007.
88(4): 583
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000247425900281
23.
61326 HIV-LS-379;
WOS-HIV-7/20/2007
Anti-Hiv Dendrimeric Peptides
Yu, Q. et al.
Biopolymers 2007.
88(4): 603
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000247425900359
24.
61327 HIV-LS-379;
WOS-HIV-7/20/2007
Testing Antiretroviral Drug Efficacy in Conventional Mice Infected With
Chimeric Hiv-1
Hadas, E. et al.
Aids 2007. 21 (8):
905-909
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246754100002
25.
61328 HIV-LS-379;
WOS-HIV-7/20/2007
High-Throughput Real-Time Assay Based on Molecular Beacons for Hiv-1
Integrase 3 '-Processing Reaction
He, H. et al.
Acta Pharmacologica Sinica 2007. 28(6): 811-817
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000246756300009
26.
61329 HIV-LS-379;
PUBMED-HIV-7/23/2007
Design of helical, oligomeric HIV-1 fusion inhibitor peptides with potent
activity against enfuvirtide-resistant virus
Dwyer, JJ, Wilson, KL, Davison, DK, Freel, SA, Seedorff, JE, Wring, SA,
Tvermoes, NA, Matthews, TJ, Greenberg, ML, and Delmedico,
MK
Proc Natl Acad Sci U S A 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
27.
61330 HIV-LS-379;
PUBMED-HIV-7/23/2007
In Vitro Antiviral Activity and Cross-Resistance Profile of PL-100, a
Next Generation Protease Inhibitor of Human Immunodeficiency Virus Type
1
Dandache, S, Sevigny, G, Yelle, J, Stranix, BR, Parkin, N, Schapiro, JM,
Wainberg, MA, and Wu, JJ
Antimicrob Agents Chemother 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
28.
61331 HIV-LS-379;
PUBMED-HIV-7/23/2007
N(2)-Benzyloxycarbonylguan-9-yl Acetic Acid Derivatives as HIV-1 Reverse
Transcriptase Non-Nucleoside Inhibitors with Decreased Loss of Potency Against
Common Drug-Resistance Mutations
Adebambo, KF, Zanoli, S, Thomas, MG, Cancio, R, Howarth, NM, and Maga,
G
ChemMedChem 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
29.
61332 HIV-LS-379;
PUBMED-HIV-7/23/2007
Protein-protein interactions as new targets for drug design: virtual and
experimental approaches
Ivanov, AS, Gnedenko, OV, Molnar, AA, Mezentsev, YV, Lisitsa, AV, and
Archakov, AI
J Bioinform Comput Biol 2007. 5(2b): 579-92
View Data on the NIAID Therapeutics Website
HYPERLINK:
30.
61333 HIV-LS-379;
PUBMED-HIV-7/23/2007
Potent inhibition of HIV-1 replication by novel non-peptidyl small
molecule inhibitors of protease dimerization
Koh, Y, Matsumi, S, Das, D, Amano, M, Davis, DA, Li, J, Leschenko, S,
Baldridge, A, Shioda, T, Yarchoan, R, Ghosh, AK, and Mitsuya,
H
J Biol Chem 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
31.
61334 HIV-LS-379;
PUBMED-HIV-7/23/2007
Iron chelators ICL670 and 311 inhibit HIV-1 transcription
Debebe, Z, Ammosova, T, Jerebtsova, M, Kurantsin-Mills, J, Niu, X,
Charles, S, Richardson, DR, Ray, PE, Gordeuk, VR, and Nekhai,
S
Virology 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
32.
61335 HIV-LS-379;
PUBMED-HIV-7/23/2007
Ketoconazole is inferior to ritonavir as an alternative booster for
saquinavir in a once daily regimen in Thai HIV-1 infected
patients
Autar, RS, Wit, FW, Sankote, J, Sutthichom, D, Kimenai, E, Hassink, E,
Hill, A, Cooper, DA, Phanuphak, P, Lange, JM, Burger, DM, and Ruxrungtham,
K
AIDS 2007. 21 (12):
1535-1539
View Data on the NIAID Therapeutics Website
HYPERLINK:
33.
61336 HIV-LS-379;
PUBMED-HIV-7/23/2007
New developments in diketo-containing inhibitors of HIV-1
integrase
Zhao, G, Wang, C, Liu, C, and Lou, H
Mini Rev Med Chem 2007.
7(7): 707-25
View Data on the NIAID Therapeutics Website
HYPERLINK:
34.
61337 HIV-LS-379;
PUBMED-HIV-7/23/2007
Synthesis and biological evaluation of 2,3-diaryl
substituted-1,3-thiazolidin-4-ones as anti-HIV agents
Rawal, RK, Tripathi, RK, Katti, SB, Pannecouque, C, and De, Clercq
E
Med Chem 2007. 3(4):
355-63
View Data on the NIAID Therapeutics Website
HYPERLINK:
35.
61338 HIV-LS-379;
PUBMED-HIV-7/23/2007
An Update in the Development of HIV Entry Inhibitors
Rusconi, S, Scozzafava, A, Mastrolorenzo, A, and Supuran,
CT
Curr Top Med Chem 2007.
7(13): 1273-89
View Data on the NIAID Therapeutics Website
HYPERLINK:
36.
61339 HIV-LS-379;
PUBMED-HIV-7/23/2007
Bis and tris indole alkaloids from marine organisms: new leads for drug
discovery
Gupta, L, Talwar, A, and Chauhan, PM
Curr Med Chem 2007.
14(16): 1789-803
View Data on the NIAID Therapeutics Website
HYPERLINK:
37.
61340 HIV-LS-379;
PUBMED-HIV-7/23/2007
HIV Integrase Inhibitors: From Diketoacids to Heterocyclic Templates: A
History of HIV Integrase Medicinal Chemistry at Merck West Point and Merck Rome
(IRBM)
Egbertson, MS
Curr Top Med Chem 2007.
7(13): 1251-72
View Data on the NIAID Therapeutics Website
HYPERLINK:
38.
61341 HIV-LS-379;
PUBMED-HIV-7/23/2007
HIV-1 Integrase: From Biology to Chemotherapeutics
Zeinalipour-Loizidou, E, Nicolaou, C, Nicolaides, A, and Kostrikis,
LG
Curr HIV Res 2007.
5(4): 365-88
View Data on the NIAID Therapeutics Website
HYPERLINK:
39.
61342 HIV-LS-379;
PUBMED-HIV-7/23/2007
In vitro pre- and post-exposure prophylaxis using HIV inhibitors as
microbicides against cell-free or cell-associated HIV-1
infection
Terrazas-Aranda, K, Van Herrewege, Y, Lewi, PJ, Van Roey, J, and Vanham,
G
Antivir Chem Chemother 2007.
18(3): 141-151
View Data on the NIAID Therapeutics Website
HYPERLINK:
40.
61343 HIV-LS-379;
PUBMED-HIV-7/23/2007
A Versatile Route to C-6 Arylmethyl-Functionalized S-DABO and Related
Analogues
Radi, M, Contemori, L, Castagnolo, D, Spinosa, R, Este, JA, Massa, S, and
Botta, M
Org
Lett 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
41.
61344 HIV-LS-379;
PUBMED-HIV-7/23/2007
Inhibition of HIV-1 replication by P-TEFb inhibitors DRB, seliciclib and
flavopiridol correlates with release of free P-TEFb from the large, inactive
form of the complex
Biglione, S, Byers, SA, Price, JP, Nguyen, VT, Bensaude, O, Price, DH,
and Maury, W
Retrovirology 2007.
4(1): 47
View Data on the NIAID Therapeutics Website
HYPERLINK:
42.
61345 HIV-LS-379;
PUBMED-HIV-7/23/2007
Anti-Vpr Activities of Heat Shock Protein 27
Liang, D, Benko, Z, Agbottah, E, Bukrinsky, M, and Zhao,
RY
Mol Med 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
43.
61346 HIV-LS-379;
PUBMED-HIV-7/23/2007
In vitro Suppression of K65R Reverse Transcriptase-mediated Tenofovir-
and Adefovir-5' Diphosphate Resistance Conferred by the Borano-phosphonate
Derivatives
Frangeul, A, Barral, K, Alvarez, K, and Canard, B
Antimicrob Agents Chemother 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
44.
61347 HIV-LS-379;
PUBMED-HIV-7/23/2007
Evaluation of the In Vitro Antiviral Activity of the Novel, Tyrosyl-based
Human Immunodeficiency Virus Type 1 Protease Inhibitor Brecanavir (BCV,
GW640385, 385) in Combination with Other Antiretrovirals and Against a Panel of
Protease Inhibitor-Resistant HIV
Hazen, R, Harvey, R, Ferris, R, Craig, C, Yates, P, Griffin, P, Miller,
J, Kaldor, I, Ray, J, Samano, V, Furfine, E, Spaltenstein, A, Hale, M, Tung, R,
St, Clair M, Hanlon, M, and Boone, L
Antimicrob Agents Chemother 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
45.
61348 HIV-LS-379;
PUBMED-HIV-7/23/2007
Bioinformatic approaches for modeling the substrate specificity of HIV-1
protease: an overview
Rognvaldsson, T, You, L, and Garwicz, D
Expert Rev Mol Diagn 2007.
7(4): 435-51
View Data on the NIAID Therapeutics Website
HYPERLINK:
46.
61349 HIV-LS-379;
PUBMED-HIV-7/23/2007
HIV entry inhibitors
Este, JA and Telenti, A
Lancet 2007.
370(9581): 81-8
View Data on the NIAID Therapeutics Website
HYPERLINK:
47.
61350 HIV-LS-379;
PUBMED-HIV-7/23/2007
Rationally Designed Dual Inhibitors of HIV Reverse Transcriptase and
Integrase
Wang, Z, Bennett, EM, Wilson, DJ, Salomon, C, and Vince,
R
J Med Chem 2007.
50(15): 3416-9
View Data on the NIAID Therapeutics Website
HYPERLINK:
48.
61351 HIV-LS-379;
PUBMED-HIV-7/23/2007
Benzyl amide-ketoacid inhibitors of HIV-integrase
Walker, MA, Johnson, T, Naidu, BN, Banville, J, Remillard, R, Plamondon,
S, Martel, A, Li, C, Torri, A, Samanta, H, Lin, Z, Dicker, I, Krystal, M, and
Meanwell, NA
Bioorg Med Chem Lett 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
49.
61352 HIV-LS-379;
PUBMED-HIV-7/23/2007
Diels-Alder Approach for the Construction of Halogenated, o-Nitro Biaryl
Templates and Application to the Total Synthesis of the Anti-HIV Agent
Siamenol
Naffziger, MR, Ashburn, BO, Perkins, JR, and Carter,
RG
J Org Chem 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
50.
61353 HIV-LS-379;
PUBMED-HIV-7/23/2007
Suppression of HIV replication using RNA interference against HIV-1
integrase
Lau, TS, Li, Y, Kameoka, M, Ng, TB, and Wan, DC
FEBS Lett 2007.
581(17): 3253-9
View Data on the NIAID Therapeutics Website
HYPERLINK:
51.
61354 HIV-LS-379;
PUBMED-HIV-7/23/2007