ONLINE DATABASE SEARCH -
DMID-LS-141-MEMO
1.
60478 DMID-LS-141;
WOS-DMID-3/26/2007
The Histone Deacetylase Inhibitor Fk228 Given Prior to Adenovirus
Infection Can Boost Infection in Melanoma Xenograft Model
Systems
Goldsmith, M. et
al.
Molecular Cancer Therapeutics 2007. 6(2): 496-505
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000244262700010
2.
60479 DMID-LS-141;
PUBMED-DMID-3/26/2007
Reduction of the infectivity of hepatitis C virus pseudoparticles by
incorporation of misfolded glycoproteins induced by glucosidase
inhibitors
Chapel, C, Garcia, C, Bartosch, B, Roingeard, P, Zitzmann, N, Cosset, FL,
Dubuisson, J, Dwek, RA, Trepo, C, Zoulim, F, and Durantel,
D
J Gen Virol 2007.
88(Pt 4): 1133-43
View Data on the NIAID Therapeutics Website
HYPERLINK:
3.
60480 DMID-LS-141;
WOS-DMID-3/26/2007
Chlorpromazine and Apigenin Reduce Adenovirus Replication and Decrease
Replication Associated Toxicity
Kanerva, A. et al.
Journal of Gene Medicine 2007. 9(1): 3-9
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000244399800001
4.
60481 DMID-LS-141;
PUBMED-DMID-3/26/2007
Relationship between HBV genotypes and anti-viral therapeutic efficacy of
interferon-alpha
Ma, JC, Wang, LW, Li, XJ, Liao, YF, Hu, XY, and Gong,
ZJ
Hepatobiliary Pancreat Dis Int 2007. 6(2): 166-71
View Data on the NIAID Therapeutics Website
HYPERLINK:
5.
60482 DMID-LS-141;
PUBMED-DMID-3/26/2007
In vitro activity of
2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]-pyrimidine against
multidrug-resistant hepatitis B virus (HBV) mutants
Brunelle, MN, Lucifora, J, Neyts, J, Villet, S, Holy, A, Trepo, C, and
Zoulim, F
Antimicrob
Agents Chemother 2007.
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HYPERLINK:
6.
60483 DMID-LS-141;
PUBMED-DMID-3/26/2007
Evolution of Resistant Mutant M414T in HCV Replicon Cells Treated with
Polymerase Inhibitor A-782759
Lu, L, Mo, H, Pilot-Matias, TJ, and Molla, A
Antimicrob Agents Chemother
2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
7.
60484 DMID-LS-141;
WOS-DMID-3/26/2007
Discovery of Novel Antiviral Leads for the Treatment of Hantavirus
Infections
Chung, D. et al.
American Journal of Tropical Medicine and Hygiene 2006 . 75(5): 277
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000242343901401
8.
60485 DMID-LS-141;
PUBMED-DMID-3/26/2007
Pyranone, Thiopyranone, and Pyridone Inhibitors of Phosphatidylinositol
3-Kinase Related Kinases. Structure-Activity Relationships for DNA-Dependent
Protein Kinase Inhibition, and Identification of the First Potent and Selective
Inhibitor of the Ataxia Telangiectasia Mutated Kinase
Hollick, JJ, Rigoreau, LJ, Cano-Soumillac, C, Cockcroft, X, Curtin, NJ,
Frigerio, M, Golding, BT, Guiard, S, Hardcastle, IR, Hickson, I, Hummersone, MG,
Menear, KA, Martin, NM, Matthews, I, Newell, DR, Ord, R, Richardson, CJ, Smith,
GC, and Griffin, RJ
J Med Chem 2007.
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HYPERLINK:
9.
60486 DMID-LS-141;
PUBMED-DMID-3/26/2007
Production and characterization of monoclonal antibodies against
different epitopes of Ebola virus antigens
Shahhosseini, S, Das, D, Qiu, X, Feldmann, H, Jones, SM, and Suresh,
MR
J Virol Methods 2007.
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HYPERLINK:
10.
60487 DMID-LS-141;
PUBMED-DMID-3/26/2007
Imidazo[1,2-a]pyridines with potent activity against
herpesviruses
Gudmundsson, KS and Johns, BA
Bioorg Med Chem Lett 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
11.
60488 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
2-METHYLTHIO-6-NITRO-1,2,4-TRIAZOLO[5,1-C]-1,2,4-TRIAZINE-7(4H)-ONE
SODIUM SALT DIHYDRATE POSSESSING ANTIVIRAL ACTIVITY
Chupakhin, ON, Rusinov, VL, Ulomskii, EN, Charushin, VN, Petrov, AYu, and
Kiselev, OI
PATENT: RU
2294936 ISSUE DATE:
20070310
APPLICATION: 2005-54714 PP:
12pp.
ASSIGNEE: (Gos. Obraz.
Uchrezhd. Vyssh. Prof. Obraz. Ural'skii Gos. Tekhn. Univ. -UPI, Russia and OOO
Nauchno-Tekhn. Predpriyatie \"Ligand\")
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HYPERLINK:
12.
60489 DMID-LS-141;
PUBMED-DMID-3/26/2007
Application of the Phosphoramidate ProTide Approach to 4'-Azidouridine
Confers Sub-micromolar Potency versus Hepatitis C Virus on an Inactive
Nucleoside
Perrone, P, Luoni, GM, Kelleher, MR, Daverio, F, Angell, A, Mulready, S,
Congiatu, C, Rajyaguru, S, Martin, JA, Leveque, V, Pogam, SL, Najera, I, Klumpp,
K, Smith, DB, and McGuigan, C
J Med Chem 2007.
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HYPERLINK:
13.
60490 DMID-LS-141;
PUBMED-DMID-3/26/2007
Synthesis of novel 2'-methyl carbovir analogues as potent antiviral
agents
Hong, JH
Arch Pharm Res 2007.
30(2): 131-137
View Data on the NIAID Therapeutics Website
HYPERLINK:
14.
60491 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Synthesis and evaluation of a group of selective inhibitors of Ebola cell
entry
Yermolina, Maria V, Wang, Jizhen, Wardrop, Duncan J, and Wang,
Lijun
Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United
States, March 25-29, 2007
2007.: MEDI-062
View Data on the NIAID Therapeutics Website
HYPERLINK:
15.
60492 DMID-LS-141;
PUBMED-DMID-3/26/2007
In vitro antiviral activity of Chamaecrista nictitans (Fabaceae) against
herpes simplex virus: biological characterization of mechanisms of
action
Herrero, Uribe L, Chaves, Olarte E, and Tamayo, Castillo
G
Rev Biol Trop 2004.
52(3): 807-16
View Data on the NIAID Therapeutics Website
HYPERLINK:
16.
60493 DMID-LS-141;
PUBMED-DMID-3/26/2007
Antiviral triterpenoids from the medicinal plant Schefflera
heptaphylla
Li, Y, Jiang, R, Ooi, LS, But, PP, and Ooi, VE
Phytother Res 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
17.
60494 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Preparation of seven-membered sugar ring nucleoside analogs as antiviral
prodrug agents
Storer, Richard, Gosselin, Gilles, Dukhan, David, Leroy, Frederic,
Meillon, Jean-Christophe, and Converd, Thierry
PATENT: WO
2007025043 ISSUE DATE: 20070301
APPLICATION: 2006 PP:
195pp.
ASSIGNEE: (Idenix
Pharmaceuticals, Inc. USA and Centre National de la Recherche
Scientifique)
View Data on the NIAID Therapeutics Website
HYPERLINK:
18.
60495 DMID-LS-141;
WOS-DMID-3/26/2007
Ribavirin, Human
Convalescent Plasma and Anti-Beta(3) Integrin Antibody Inhibit Infection by Sin
Nombre Virus in the Deer Mouse Model
Medina, R. et al.
Journal of General Virology 2007. 88: 493-505
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243987100018
19.
60496 DMID-LS-141;
PUBMED-DMID-3/26/2007
Superior efficacy of helicase-primase inhibitor BAY 57-1293 for herpes
infection and latency in the guinea pig model of human genital herpes
disease
Baumeister, J, Fischer, R, Eckenberg, P, Henninger, K,
Ruebsamen-Waigmann, H, and Kleymann, G
Antivir Chem Chemother 2007.
18(1): 35-48
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HYPERLINK:
20.
60497 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Human antibodies and immunoconjugates capable of neutralizing West Nile
virus and other flaviviruses, and uses in diagnosis, prophylaxis and
therapy
Throsby, Mark and De Kruif, Cornelis Adriaan
PATENT: US
2007042359 ISSUE DATE: 20070222
APPLICATION: 51 PP: 43pp.,
Cont.-in-part of Appl. No. PCT/EP05-052160.
ASSIGNEE: (Crucell Holland
B.V., Neth.
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HYPERLINK:
21.
60498 DMID-LS-141;
PUBMED-DMID-3/26/2007
High frequency of spontaneous helicase-primase inhibitor (BAY 57-1293)
drug-resistant variants in certain laboratory isolates of HSV-1
Biswas, S, Swift, M, and Field, HJ
Antivir Chem Chemother 2007.
18(1): 13-23
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HYPERLINK:
22.
60499 DMID-LS-141;
PUBMED-DMID-3/26/2007
Antiviral activity of human beta-defensin 3 against vaccinia
virus
Howell, MD, Streib, JE, and Leung, DY
J Allergy Clin Immunol 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
23.
60500 DMID-LS-141;
PUBMED-DMID-3/26/2007
Influenza neuraminidase antibodies provide partial protection for
chickens against high pathogenic avian influenza infection
Sylte, MJ, Hubby, B, and Suarez, DL
Vaccine 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
24.
60501 DMID-LS-141;
PUBMED-DMID-3/26/2007
Interferon alfa (pegylated and non-pegylated) and ribavirin for the
treatment of mild chronic hepatitis C: a systematic review and economic
evaluation
Shepherd, J, Jones, J, Hartwell, D, Davidson, P, Price, A, and Waugh,
N
Health Technol Assess 2007.
11(11): 1-224
View Data on the NIAID Therapeutics Website
HYPERLINK:
25.
60502 DMID-LS-141;
PUBMED-DMID-3/26/2007
Antiviral effects of antisense morpholino oligomers in murine coronavirus
infection models
Burrer, R, Neuman, BW, Ting, JP, Stein, DA, Moulton, HM, Iversen, PL,
Kuhn, P, and Buchmeier, MJ
J Virol 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
26.
60503 DMID-LS-141;
PUBMED-DMID-3/26/2007
Updates on antiviral therapy for chronic hepatitis C
Toniutto, P, Fabris, C, Bitetto, D, Fornasiere, E, Rapetti, R, and
Pirisi, M
Discov Med 2007.
7(37): 27-32
View Data on the NIAID Therapeutics Website
HYPERLINK:
27.
60504 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Synthesis and antiviral activity of Sulforamate
derivatives
Moriarty, Robert M, Naithani, Rajesh, Surve, Bhushan C, Tiwari, Vaibhav,
and Shukla, Deepak
Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United
States, March 25-29, 2007
2007.: MEDI-064
View Data on the NIAID Therapeutics Website
HYPERLINK:
28.
60505 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Synthesis and antiviral activity of Abyssinone II analogs
Moriarty, Robert M, Surve, Bhushan C, Naithani, Rajesh, Chandersekera,
Susantha N, Tiwari, Vaibhav, and Shukla, Deepak
Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United
States, March 25-29, 2007
2007.: MEDI-063
View Data on the NIAID Therapeutics Website
HYPERLINK:
29.
60506 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Optimizing the synthesis of N-methanocarbathymidine, a potent and
selective antiviral agent
Marquez, Victor E and Ludek, Olaf R
Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United
States, March 25-29, 2007
2007.: MEDI-061
View Data on the NIAID Therapeutics Website
HYPERLINK:
30.
60507 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Protonated antimicrobial and antiviral compounds and methods for their
use
Dale, Roderic MK
PATENT: US
2007053971 ISSUE DATE: 20070308
APPLICATION: 2006-28663 PP:
42pp., Cont.-in-part of U.S. Ser. No. 937,094.
ASSIGNEE: (Oligos Etc., Inc
USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
31.
60508 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Antiviral compositions containing p-hydroxybenzoic acid and analogues for
prevention and treatment of skin virus infections
Zhang, Qingmin and Qin, Weihua
PATENT: WO
2007014514 ISSUE DATE: 20070208
APPLICATION: 2006 PP:
18pp.
ASSIGNEE: (Shenghua
Guangzhou Pharmaceutical Science & Technology Co., Ltd. Peop. Rep.
China
View Data on the NIAID Therapeutics Website
HYPERLINK:
32.
60509 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Use of acyl thiouracil derivatives as antiviral drug
Zhou, Pei, Feng, Meiqing, Sun, Chuanwen, Huang, Hai, and Zhou,
Wei
PATENT: CN
1903203 ISSUE DATE:
20070131
APPLICATION: 1002-8153 PP:
11pp.
ASSIGNEE: (Fudan University,
Peop. Rep. China
View Data on the NIAID Therapeutics Website
HYPERLINK:
33.
60510 DMID-LS-141;
PUBMED-DMID-3/26/2007
The effects of DNA methylation and histone deacetylase inhibitors on
human papillomavirus early gene expression in cervical cancer, an in vitro and
clinical study
de la Cruz-Hernandez, E, Perez-Cardenas, E, Contreras-Paredes, A, Cantu,
D, Mohar, A, Lizano, M, and Duenas-Gonzalez, A
Virol J 2007 . 4:
18
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HYPERLINK:
34.
60511 DMID-LS-141;
WOS-DMID-3/26/2007
Pf-03491390, (Formerly Idn-6556) a Pancaspase Inhibitor, Is
Well-Tolerated and Effectively Reduces Raised Aminotransferases (Alt and Ast) in
Chronic Active Hepatitis C (Hcv) Patients (Pts)
Shiffman, M. et al.
Hepatology 2006.
44(4): 224A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362300096
35.
60512 DMID-LS-141;
WOS-DMID-3/26/2007
Inhibition of Hepatitis C Viral (Hcv) Replication by in-Vivo Dimerization
of Stat1
Li, X. et al.
Hepatology 2006.
44(4): 307A-308A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362300318
36.
60513 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Antisense antiviral compound and method for treating picornavirus
infection
Stein, David A, Bestwick, Richard K, Iversen, Patrick L, and Weller,
Dwight D
PATENT: WO
2007030691 ISSUE DATE: 20070315
APPLICATION: 2006 PP:
51pp.
ASSIGNEE: (Avi Biopharma,
Inc. USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
37.
60514 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Preparation of
pyridazine derivatives as picornavirus inhibitors
Li, Song, Mi, Chunlai, Zheng, Zhibing, Zhao, Guoming, Zhou, Xinbo, and
Gong, Zehui
PATENT: CN
1887875 ISSUE DATE:
20070103
APPLICATION: 1008-1813 PP:
38pp.
ASSIGNEE: (Institute of
Pharmacology & Toxicology, Academy of Military Medical Sciences Peop. Rep.
China
View Data on the NIAID Therapeutics Website
HYPERLINK:
38.
60515 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Tetrahydrocarbazoles as potential therapeutic agents for human
papillomavirus infection
Sebahar, Paul R, Brown, Kevin W, Gudmundsson, Kristjan S, Harvey, Robert,
Richardson, Leah, and Sethna, Phiroze
Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United
States, March 25-29, 2007
2007.: MEDI-087
View Data on the NIAID Therapeutics Website
HYPERLINK:
39.
60516 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Methods for engineering artificial zinc finger proteins for inhibiting
DNA replication of human papillomavirus
Sera, Takashi
PATENT: WO
2007024029 ISSUE DATE: 20070301
APPLICATION: 2006 PP:
53pp.
ASSIGNEE: (Kyoto University,
Japan
View Data on the NIAID Therapeutics Website
HYPERLINK:
40.
60517 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Antiviral compositions containing hydroxybenzoic acid ester and analogues
for prevention and treatment of virus infections
Zhang, Qingmin and Qin, Weihua
PATENT: WO
2007014515 ISSUE DATE: 20070208
APPLICATION: 2006 PP:
23pp.
ASSIGNEE: (Shenghua
(Guangzhou) Pharmaceutical Science & Technology Co., Ltd. Peop. Rep.
China
View Data on the NIAID Therapeutics Website
HYPERLINK:
41.
60518 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Docking and 3-D-QSAR analysis of HCV NS5B RNA-dependent RNA polymerase
inhibitors based on a common benzothiadiazine scaffold
Odde, Srinivas, Sivaprakasam, Prasanna, and Doerksen, Robert
J
Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United
States, March 25-29, 2007
2007.: MEDI-085
View Data on the NIAID Therapeutics Website
HYPERLINK:
42.
60519 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Tetracyclic indole derivatives as antiviral agents
Narjes, Frank and Stansfield, Ian
PATENT: WO
2007029029 ISSUE DATE: 20070315
APPLICATION: 2006 PP:
29pp.
ASSIGNEE: (Istituto di
Ricerche di Biologia Molecolare P. Angeletti S.p.A.,
Italy
View Data on the NIAID Therapeutics Website
HYPERLINK:
43.
60520 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Quinazoline derivatives as antiviral agents
Donghi, Monica, Ferrara, Marco, Koch, Uwe, Narjes, Frank, Ontoria
Ontoria, Jesus Maria, and Summa, Vincenzo
PATENT: WO
2007028789 ISSUE DATE: 20070315
APPLICATION: 2006 PP:
56pp.
ASSIGNEE: (Istituto di
Ricerche di Biologia Molecolare P. Angeletti S.p.A.,
Italy
View Data on the NIAID Therapeutics Website
HYPERLINK:
44.
60521 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Preparation of 3',5'-cyclic nucleoside analogs as antiviral agents for
treatment of HCV
Gunic, Esmir, Hong, Zhi, and Girardet, Jean-Luc
PATENT: WO
2007027248 ISSUE DATE: 20070308
APPLICATION: 2006 PP:
158pp.
ASSIGNEE: (Valeant Research
& Development, USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
45.
60522 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Phenylglycine as a
novel P2 scaffold in hepatitis C virus NS3 protease inhibitors
Oertqvist, Pernilla, Peterson, Shane D, Aakerblom, Eva, Gossas, Thomas,
Sabnis, Yogesh A, Fransson, Rebecca, Lindeberg, Gunnar, Danielson, UHelena,
Karlen, Anders, and Sandstroem, Anja
Bioorganic & Medicinal Chemistry 2007. 15(3): 1448-1474
View Data on the NIAID Therapeutics Website
HYPERLINK:
46.
60523 DMID-LS-141;
WOS-DMID-3/26/2007
Role of Combination Antiviral Therapy in Pandemic
Influenza
Tsiodras, S., Mooney, J., and Hatzakilis, A.
British Medical Journal 2007. 334(7588): 293-294
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000244654100031
47.
60524 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Preparation of spiroisoxazoline-based peptidomimetics as inhibitors of
serine proteases, particularly HCV NS3-NS4A protease
Cottrell, Kevin M, Maxwell, John, Tang, Qing, Grillot, Anne-Laure, Le
Tiran, Arnaud, and Perola, Emanuele
PATENT: WO
2007025307 ISSUE DATE: 20070301
APPLICATION: 2006 PP:
489pp.
ASSIGNEE: (Vertex
Pharmaceuticals Incorporated, USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
48.
60525 DMID-LS-141;
WOS-DMID-3/26/2007
Platinum(Ii) and Palladium(Ii) Complexes of Pyridine-2-Carbaldehyde
Thiosemicarbazone as Alternative Antiherpes Simplex Virus Agents
Kovala-Demertzi, D. et al.
Bioinorganic Chemistry and Applications
2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000244557200001
49.
60526 DMID-LS-141;
SCIFINDER-DMID-3/26/2007
Preparation of amino acid-containing nucleotide phosphoramidates as
antiviral agents
Klumpp, Klaus, Martin, Joseph Armstrong, Mcguigan, Christoph