ONLINE DATABASE SEARCH -
DMID-LS-140-MEMO
1.
60358 DMID-LS-140;
PUBMED-DMID-3/12/2007
Antiviral strategies against human coronaviruses
Pyrc, K, Berkhout, B, and van der Hoek, L
Infect Disord Drug Targets 2007. 7(1): 59-66
View Data on the NIAID Therapeutics Website
HYPERLINK:
2.
60359 DMID-LS-140;
PUBMED-DMID-3/12/2007
Novel targets for the development of anti-herpes
compounds
Greco, A, Diaz, JJ, Thouvenot, D, and Morfin, F
Infect Disord Drug Targets 2007. 7(1): 11-8
View Data on the NIAID Therapeutics Website
HYPERLINK:
3.
60360 DMID-LS-140;
WOS-DMID-3/12/2007
Specific Inhibition of Hbv Replication in Vitro and in Vivo With
Expressed Long Hairpin Rna
Weinberg, M. et al.
Molecular Therapy
2007. 15(3):
534-541
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000244405700017
4.
60361 DMID-LS-140;
WOS-DMID-3/12/2007
Antivirals of Ethnomedicinal Origin: Structure-Activity Relationship and
Scope
Chattopadhyay, D. and Naik, T.
Mini-Reviews in Medicinal Chemistry 2007. 7(3): 275-301
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000244158200006
5.
60362 DMID-LS-140;
PUBMED-DMID-3/12/2007
1,4-Benzodiazepines as Inhibitors of Respiratory Syncytial Virus. The
Identification of a Clinical Candidate
Henderson, EA, Alber, DG, Baxter, RC, Bithell, SK, Budworth, J, Carter,
MC, Chubb, A, Cockerill, GS, Dowdell, VC, Fraser, IJ, Harris, RA, Keegan, SJ,
Kelsey, RD, Lumley, JA, Stables, JN, Weerasekera, N, Wilson, LJ, and Powell,
KL
J Med Chem 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
6.
60363 DMID-LS-140;
PUBMED-DMID-3/12/2007
Functional characterization of cis and trans protease activity of the
flavivirus NS2B-NS3 protease
Bera, AK, Kuhn, RJ, and Smith, JL
J Biol Chem 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
7.
60364 DMID-LS-140;
WOS-DMID-3/12/2007
Anti-Viral Effects, Pharmacokinetics and Safety of Two Human Monoclonal
Anti-Hbs (Libivirumab/Exbivirumab) Versus Hepatitis B Immune Globulin (Hbig) in
Hepatits B Virus (Hbv) in Liver Transplant (Lt) Recipients
Shouval, D. et al.
Hepatology 2006.
44(4): 196A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362300023
8.
60365 DMID-LS-140;
PUBMED-DMID-3/12/2007
An efficient synthesis of 3-fluoro-5-thio-xylofuranosyl nucleosides of
thymine, uracil, and 5-fluorouracil as potential antitumor or/and antiviral
agents
Tsoukala,
E, Agelis, G, Dolinsek, J, Botic, T, Cencic, A, and Komiotis,
D
Bioorg Med Chem 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
9.
60366 DMID-LS-140;
EMBASE-DMID-3/12/2007
Expression and purification of a two-component flaviviral proteinase
resistant to autocleavage at the NS2B-NS3 junction region
Shiryaev, Sergey A, Aleshin, Alexander E, Ratnikov, Boris I, Smith,
Jeffrey W, Liddington, Robert C, and Strongin, Alex Y
Protein Expression and Purification 2007. 52(2): 334-339
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://www.sciencedirect.com/science/article/B6WPJ-4MG5WBS-2/2/62d8c08d90c5dc149c1cea734e4bae7c
10.
60367 DMID-LS-140;
PUBMED-DMID-3/12/2007
Synthesis and biological evaluation of nucleoside analogues having
6-chloropurine as anti-SARS-CoV agents
Ikejiri, M, Saijo, M, Morikawa, S, Fukushi, S, Mizutani, T, Kurane, I,
and Maruyama, T
Bioorg Med Chem Lett 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
11.
60368 DMID-LS-140;
WOS-DMID-3/12/2007
Inhibitory Activity of the
2,4-Diamino-6-[2-(Phosphonomethoxy)Ethoxy]-Pyrimidine (Pmeo) Against Wild Type
and Drug Resistant Mutants of Hbv
Brunelle, M. et al.
Hepatology 2006.
44(4): 223A-224A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362300095
12.
60369 DMID-LS-140;
PUBMED-DMID-3/12/2007
Antiviral effect of octyl gallate against influenza and other RNA
viruses
Yamasaki, H, Uozaki, M, Katsuyama, Y, Utsunomiya, H, Arakawa, T, Higuchi,
M, Higuti, T, and Koyama, AH
Int J Mol Med 2007.
19(4): 685-8
View Data on the NIAID Therapeutics Website
HYPERLINK:
13.
60370 DMID-LS-140;
WOS-DMID-3/12/2007
Discovery, Characterization and Anti-Hcv Activity of a Novel Ns5b
Inhibitor
Wagner, R. et al.
Hepatology 2006.
44(4): 236A-237A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362300129
14.
60371 DMID-LS-140;
EMBASE-DMID-3/12/2007
Characterization of the Intracellular Metabolism of
[beta]-d-2'-Deoxy-2'-Fluoro-2'-C-Methyl-Cytidine and the Inhibition of HCV
Polymerase NS5B by its 5'-Triphosphate Species
Ma, Han, Jiang, Wen-Rong, Robledo, Nicole, Leveque, Vincent, Ali, Samir,
Smith, David, Masjedizadeh, Mohammad, Lara-Jaime, Teresa, Cammack, Nick, Klumpp,
Klaus, and Symons, Julian
Antiviral Research 2007.
In Press, Uncorrected Proof: 2874
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://www.sciencedirect.com/science/article/B6T2H-4N3X611-V/2/b924071a60466bcc30a87bdc40f6de20
15.
60372 DMID-LS-140;
PUBMED-DMID-3/12/2007
Hepatitis C Virus Infection-Pathobiology and Implications for New
Therapeutic Options
Davis, GL, Krawczynski, K, and Szabo, G
Dig Dis Sci 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
16.
60373 DMID-LS-140;
EMBASE-DMID-3/12/2007
Sub Micromolar Inhibitors of HCV Generated from Inactive Nucleosides by
Application of ProTide Technology
McGuigan, Christopher, Perrone, Plinio, Luoni, Giovanna, Kelleher, Mary
Rose, Daverio, Felice, Angell, Annette, Mulready, Sinead, Congiatu, Costantino,
Rajyaguru, Sonal, Martin, Joseph, Leveque, Vincent, Le Pogam, Sophie, Najera,
Isabel, Klumpp, Klaus, and Smith, David
Antiviral Research 2007.
In Press, Uncorrected Proof: 2874
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://www.sciencedirect.com/science/article/B6T2H-4N3X611-W/2/d6f610f40226ba9e4c6902e9e026157c
17.
60374 DMID-LS-140;
EMBASE-DMID-3/12/2007
Substituted Imidazopyridines as Potent Inhibitors of Hepatitis C Virus
Replication that Target the Viral Polymerase
Vliegen,
Inge, Paeshuyse, Jan, Lehman, Laura S, Zhong, Weidong, Roofthooft, Sofie,
Dutartre, Helene, Selisko, Barbara, Canard, Bruno, Boddeker, Nina, Bondy,
Steven, Oare, David, De Clercq, Erik, Lee, William A, Purstinger, Gerhard, and
Neyts, Johan
Antiviral Research 2007.
In Press, Uncorrected Proof: 2874
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://www.sciencedirect.com/science/article/B6T2H-4N3X611-Y/2/2ad0c9e1d28b5d678adce11ed41a39f3
18.
60375 DMID-LS-140;
PUBMED-DMID-3/12/2007
6-Hydrazinopurine 2'-methyl ribonucleosides and their 5'-monophosphate
prodrugs as potent hepatitis C virus inhibitors
Gunic, E, Chow, S, Rong, F, Ramasamy, K, Raney, A, Yunzhi, Li D, Huang,
J, Hamatake, RK, Hong, Z, and Girardet, JL
Bioorg Med Chem Lett 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
19.
60376 DMID-LS-140;
PUBMED-DMID-3/12/2007
Cowaniin, a C-glucosidic ellagitannin dimer linked through catechin from
Cowania mexicana
Ito, H, Miyake, M, Nishitani, E, Miyashita, K, Yoshimura, M, Yoshida, T,
Takasaki, M, Konoshima, T, Kozuka, M, and Hatano, T
Chem Pharm Bull (Tokyo) 2007. 55(3): 492-4
View Data on the NIAID Therapeutics Website
HYPERLINK:
20.
60377 DMID-LS-140;
EMBASE-DMID-3/12/2007
7-Deaza Neplanocin Analogs Inhibit Hepatitis C Virus (HCV) in
Vitro
Kim, HJ, Wang, JN, Huang, ZH, Murray, MG, Schinazi, RF, and Chu,
CK
Antiviral Research 2007.
In Press, Uncorrected Proof: 2874
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://www.sciencedirect.com/science/article/B6T2H-4N3X611-1X/2/60d250a629a833572f8ba696a73da7d3
21.
60378 DMID-LS-140;
EMBASE-DMID-3/12/2007
Potent HCV NS5B Polymerase Inhibitors Derived From
5-Hydroxy-3(2H)-Pyridazinones: Part 2: Variation of the 2- and 6- Pyridazinone
Substituents
Zhou, Y, Li, L-S, Webber, S, Ayida, B, Bertolini, T, Sun, Z, Zhao, J,
Stankovic, N, Patel, R, Li, B, LeBrun, L, Kamran, R, Sergeeva, M, Bartkowski, D,
and Khandurina, J
Antiviral Research 2007.
In Press, Uncorrected Proof: 2874
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://www.sciencedirect.com/science/article/B6T2H-4N3X611-24/2/8a1353d17b4aafc6ad331974664f1a06
22.
60379 DMID-LS-140;
EMBASE-DMID-3/12/2007
Discovery of Two Novel Classes of Inhibitors of Hepatitis C Virus (HCV)
Replication utilizing a Dicistronic Reporter HCV Replicon High Throughput
Assay
Hao, Weidong, Weady, Peter, Maldonado, Fausto, Patick, Amy, and Duggal,
Rohit
Antiviral Research 2007.
In Press, Uncorrected Proof: 2874
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://www.sciencedirect.com/science/article/B6T2H-4N3X611-2R/2/2d89ee9fb2b7b0f84e0b43c38f04c9d8
23.
60380 DMID-LS-140;
WOS-DMID-3/12/2007
The Antiviral Efficacy of an Hcv Polymerase Inhibitor in the Chimpanzee
Model: Genotypic and Phenotypic Analyses
Chen, C. et al.
Hepatology 2006.
44(4): 342A-343A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362300407
24.
60381 DMID-LS-140;
WOS-DMID-3/12/2007
The Cyclophilin Inhibitor Debio-025 Is a Potent Inhibitor of Hepatitis C
Virus Replication in Vitro
Paeshuyse, J. et
al.
Hepatology 2006.
44(4): 346A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362300417
25.
60382 DMID-LS-140;
WOS-DMID-3/12/2007
In Vitro Antiviral Effects of Combinations of Abbott Hcv Polymerase
Inhibitors With Ifn or Ns3/4a Protease Inhibitors
Koev, G. et al.
Hepatology 2006.
44(4): 346A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362300418
26.
60383 DMID-LS-140;
PUBMED-DMID-3/12/2007
Finding new medicines for flaviviral targets
Keller, TH, Chen, YL, Knox, JE, Lim, SP, Ma, NL, Patel, SJ, Sampath, A,
Wang, QY, Yin, Z, and Vasudevan, SG
Novartis Found Symp 2006.
277: 102-14; discussion 114-9, 251-3
View Data on the NIAID Therapeutics Website
HYPERLINK:
27.
60384 DMID-LS-140;
PUBMED-DMID-3/12/2007
Towards the design of flavivirus helicase/NTPase inhibitors:
crystallographic and mutagenesis studies of the dengue virus NS3 helicase
catalytic domain
Xu,
T, Sampath, A, Chao, A, Wen, D, Nanao, M, Luo, D, Chene, P, Vasudevan, SG, and
Lescar, J
Novartis Found Symp 2006.
277: 87-97; discussion 97-101, 251-3
View Data on the NIAID Therapeutics Website
HYPERLINK:
28.
60385 DMID-LS-140;
EMBASE-DMID-3/12/2007
Enhanced Antiviral Activity of
Hexadecyloxypropyl-PME-N6-Cyclopropyl-diaminopurine Against Herpesviruses,
Hepatitis B Virus and Vaccinia Virus, In Vitro
Andrei, Graciela, Snoeck, Robert, Neyts, Johan, De Clercq, Erik,
Valiaeva, Nadejda, Beadle, James, and Hostetler, Karl
Antiviral Research 2007.
In Press, Uncorrected Proof
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://www.sciencedirect.com/science/article/B6T2H-4N3X611-47/2/e4bf5519b5d30634e74e38a81ff9d704
29.
60386 DMID-LS-140;
PUBMED-DMID-3/12/2007
Development of novel antivirals against flaviviruses
Patkar, CG and Kuhn, RJ
Novartis Found Symp 2006.
277: 41-52; discussion 52-6, 71-3, 251-3
View Data on the NIAID Therapeutics Website
HYPERLINK:
30.
60387 DMID-LS-140;
WOS-DMID-3/12/2007
In Vitro Antiviral Interactions of a Novel Hcv Inhibitor R1479 With
Interferon Alpha-2a, Ribavirin and Other Hcv Inhibitors
Jiang, W. et al.
Hepatology 2006.
44(4): 533A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302023
31.
60388 DMID-LS-140;
PUBMED-DMID-3/12/2007
Hepatitis C virus infection, cryoglobulinaemia, and
beyond
Sansonno, D, Carbone, A, De, Re V, and Dammacco, F
Rheumatology (Oxford) 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
32.
60389 DMID-LS-140;
WOS-DMID-3/12/2007
In Vitro Synergistic Antiviral Activity of Itmn-191, an Orally Active
Inhibitor of the Hepatitis C Virus (Hcv) Ns3/4a Protease, in Combination With
Peg-Interferon Alfa-2a
Tan, H., Seiwert, S., and Blatt, L.
Hepatology 2006.
44(4): 534A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302027
33.
60390 DMID-LS-140;
WOS-DMID-3/12/2007
Preclinical Evaluation of Scy-635, a Cyclophilin Inhibitor With Potent
Anti-Hcv Activity
Houck, D. and Hopkins, S.
Hepatology 2006.
44(4): 534A-535A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302028
34.
60391 DMID-LS-140;
WOS-DMID-3/12/2007
Induction of Resistance by a Novel Class of Compounds Active Against
Hepatitis C Virus With No Cross-Resistance to Ns3 Protease and Ns5b Polymerase
Inhibitors
Yang, W. et al.
Hepatology 2006.
44(4): 536A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302031
35.
60392 DMID-LS-140;
WOS-DMID-3/12/2007
A Common Molecular Pathway Leads to Inhibition of Interferon-Alpha
Signaling in Both Hepatitis B and Hepatitis C Virus Infection
Christen, V. and Heim, M.
Hepatology 2006.
44(4): 546A-547A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302059
36.
60393 DMID-LS-140;
PUBMED-DMID-3/12/2007
Synergistic copathogens--HIV-1 and HSV-2
Corey, L
N Engl J Med 2007.
356(8): 854-6
View Data on the NIAID Therapeutics Website
HYPERLINK:
37.
60394 DMID-LS-140;
WOS-DMID-3/12/2007
The Cyclophilin Inhibitor Debio-025 Has a Potent Dual Anti-Hiv and
Anti-Hcv Activity in Treatment-Naive Hiv/Hcv Co-Infected
Subjects
Flisiak, R. et al.
Hepatology 2006.
44(4): 609A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302224
38.
60395 DMID-LS-140;
WOS-DMID-3/12/2007
Interim Antiviral and Safety Data With Albumin Interferon Alfa-2b
Combined With Ribavirin in a Phase 2b Study Conducted in a Genotype 1,
Ifn-Naive, Chronic Hepatitis C Population
Mchutchison, J. et al.
Hepatology 2006.
44(4): 614A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302235
39.
60396 DMID-LS-140;
WOS-DMID-3/12/2007
Current Status of Subjects Receiving Peg-Interferon-Alfa-2a (Peg-Ifn) and
Ribavirin (Rbv) After a 14-Day Study of the Hepatitis C Protease Inhibitor
Telaprevir (Vx-950), With Peg-Ifn
Forestier, N. et
al.
Hepatology 2006.
44(4): 614A-615A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302236
40.
60397 DMID-LS-140;
EMBASE-DMID-3/12/2007
Combined Anti-Influenza Virus Effect of a Plant Polyphenol-Rich Extract
and Ribavirin
Serkedjieva, Julia and Teodosieva, Ani
Antiviral Research 2007.
In Press, Uncorrected Proof: 200
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://www.sciencedirect.com/science/article/B6T2H-4N3X611-1N/2/3e9fabc9fb7e3fd0e8942a451061591b
41.
60398 DMID-LS-140;
WOS-DMID-3/12/2007
Chloroquine Possesses a Potent Inhibitory Effect of Replication of Hcv
Replicon
Mizui, T. et al.
Hepatology 2006.
44(4): 620A-621A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302251
42.
60399 DMID-LS-140;
EMBASE-DMID-3/12/2007
Anti-Influenza A Synergistic Combination Effect of Rimantadine and
Oseltamivir in Mice
Simeonova, Lora, Galabov, Angel S, and Gegova,
Galina
Antiviral Research 2007.
In Press, Uncorrected Proof: 200
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://www.sciencedirect.com/science/article/B6T2H-4N3X611-1P/2/e4c9aa55b3c8d3576fe6f87925bb5b0a
43.
60400 DMID-LS-140;
WOS-DMID-3/12/2007
A Novel Class of Amphipathic Dna Polymers Inhibits Hepatitis C Virus
Infection by Blocking Viral Entry
Matsumura, T. et
al.
Hepatology 2006.
44(4): 693A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302444
44.
60401 DMID-LS-140;
EMBASE-DMID-3/12/2007
Susceptibility of German Porcine H3N2 Influenza A viruses Against
Existing Antiviral Drugs
Bauer, Katja, Schrader, Christina, Suess, Jochen, Wutzler, Peter, and
Schmidtke, Michaela
Antiviral Research 2007.
In Press, Uncorrected Proof: 200
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://www.sciencedirect.com/science/article/B6T2H-4N3X611-2J/2/b1e80aaf103e90f970997e34929af1d3
45.
60402 DMID-LS-140;
WOS-DMID-3/12/2007
Synthesis of Three Novel Nucleoside Analogs as Hepatitis B Virus Specific
Antiviral Reagents
Niu, J. et al.
Hepatology 2006.
44(4): 699A-700A
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000241362302461
46.
60403 DMID-LS-140;
EMBASE-DMID-3/12/2007
Pharmacodynamics of NPI-5291, an Adamantane Class Compound, for Influenza
A Viruses
McSharry, James, Zager, Kris, Weng, Qingmei, Chernoff, David, and
Drusano, George
Antiviral Research 2007.
In Press, Uncorrected Proof: 200
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://www.sciencedirect.com/science/article/B6T2H-4N3X611-2Y/2/7e20b75b882b9aa88fb8fdf48c34a0b5
47.
60404 DMID-LS-140;
EMBASE-DMID-3/12/2007
Design, Synthesis, and Biological Evaluation of Novel Anti-VZV
Agents
Derudas, Marco, McGuigan, Christopher, Snoeck, Robert, Andrei, Graciella,
De Clercq, Erik, and Balzarini, Jan
Antiviral Research 2007.
In Press, Uncorrected Proof: 200
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://www.sciencedirect.com/science/article/B6T2H-4N3X611-3W/2/30af3db89dfc6af5d29f14837ef33e5d
48.
60405 DMID-LS-140;
PUBMED-DMID-3/12/2007
In vivo and in vitro antiviral activity of hyperoside extracted from
Abelmoschus manihot (L) medik
Wu, LL, Yang, XB, Huang, ZM, Liu, HZ, and Wu, GX
Acta Pharmacol Sin 2007.
28(3): 404-9
View Data on the NIAID Therapeutics Website
HYPERLINK:
49.
60406 DMID-LS-140;
EMBASE-DMID-3/12/2007
The Ugi reaction in the generation of new nucleosides as potential
antiviral and antileishmanial agents
Fan, Xuesen, Zhang, Xinying, Bories, Christian, Loiseau, Philippe M, and
Torrence, Paul F
Bioorganic Chemistry 2007.
35(2): 121-136
View Data on the NIAID Therapeutics Website
HYPERLINK: