ONLINE DATABASE SEARCH -
DMDI-LS-139-MEMO
1.
60255 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
Pyrrolidine derivatives as immunomodulators and antiviral
agents
Nash, Robert James, Carroll, Miles William, Watson, Alison Ann, Fleet,
George William John, and Horne, Graeme
PATENT: WO
2007010266 ISSUE DATE: 20070125
APPLICATION: 2006 PP:
72pp.
ASSIGNEE: (MNL Pharma
Limited, UK
View Data on the NIAID Therapeutics Website
HYPERLINK:
2.
60256 DMID-LS-139;
PUBMED-DMID-2/26/2007
Dysoxylins A-D, Tetranortriterpenoids with Potent Anti-RSV Activity from
Dysoxylum gaudichaudianum
Chen, JL, Kernan, MR, Jolad, SD, Stoddart, CA, Bogan, M, and Cooper,
R
J Nat Prod 2007.
70(2): 312-5
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3.
60257 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
Synthetic single strand deoxynucleosides for antiviral
uses
Wang, Li-Ying, Bao, Mu-Sheng, and Yu, Yong-Li
PATENT: WO
2007012285 ISSUE DATE: 20070201
APPLICATION: 2006 PP:
62pp.
ASSIGNEE: (Changchun Huapu
Biotechnology Co., Ltd. Peop. Rep. China
View Data on the NIAID Therapeutics Website
HYPERLINK:
4.
60258 DMID-LS-139;
PUBMED-DMID-2/26/2007
Molecular diagnostics of hepatitis C virus infection: a systematic
review
Scott, JD and Gretch, DR
JAMA 2007. 297(7):
724-32
View Data on the NIAID Therapeutics Website
HYPERLINK:
5.
60259 DMID-LS-139;
PUBMED-DMID-2/26/2007
Proteases essential for human influenza virus entry into cells and their
inhibitors as potential therapeutic agents
Kido, H, Okumura, Y, Yamada, H, Le, TQ, and Yano, M
Curr Pharm Des
2007. 13(3):
403-12
View Data on the NIAID Therapeutics Website
HYPERLINK:
6.
60260 DMID-LS-139;
PUBMED-DMID-2/26/2007
Human Rhinovirus 3C Protease as a Potential Target for the Development of
Antiviral Agents
Wanga, QM and Chen, SH
Curr Protein Pept Sci 20067. 8(1): 19-27
View Data on the NIAID Therapeutics Website
HYPERLINK:
7.
60261 DMID-LS-139;
PUBMED-DMID-2/26/2007
Inhibitory effect of cinnamaldehyde, derived from Cinnamomi cortex, on
the growth of influenza A/PR/8 virus in vitro and in vivo
Hayashi, K, Imanishi, N, Kashiwayama, Y, Kawano, A, Terasawa, K, Shimada,
Y, and Ochiai, H
Antiviral Res 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
8.
60262 DMID-LS-139;
WOS-DMID-2/26/2007
Efficient Synthesis of (S)-2-(Cyclopentyloxycarbonyl)-Amino-8-Nonenoic
Acid: Key Building Block for Biln 2061, an Hcvns3 Protease
Inhibitor
Wang, X. et al.
Organic Process Research & Development 2007. 11(1): 60-63
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243560000009
9.
60263 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
Preparation of macrocyclic inhibitors of hepatitis C
virus
Raboisson, Pierre Jean-Marie Bernard, De Kock, Herman Augustinus, Hu,
Lili, Simmen, Kenneth Alan, Lindquist, Karin Charlotta, Lindstroem, Mats Stefan,
Belfrage, Anna Karin Gertrud Linnea, Waehling, Horst Juergen, Nilsson, Karl
Magnus, Samuelsson, Bengt Bertil, Rosenquist, Aasa Annica Kristina, Sahlberg,
Sven Crister, Wallberg, Hans Kristian, Kahnberg, Pia Cecilia, and Classon,
Bjoern Olof
PATENT: WO
2007014927 ISSUE DATE: 20070208
APPLICATION: 2006 PP:
158pp.
ASSIGNEE: (Tibotec
Pharmaceuticals Ltd., Ire. and Medivir AB)
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HYPERLINK:
10.
60264 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
Preparation of N-prolyl-1-aminocyclopropanecarboxylic acid peptides as
antiviral agents
Casarez, Anthony, Chaudhary, Kleem, Kim, Choung U, McMurtrie, Darren, and
Sheng, Xiaoning C
PATENT: WO
2007011658 ISSUE DATE: 20070125
APPLICATION: 2006 PP:
190pp.
ASSIGNEE: (Gilead Sciences,
Inc. USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
11.
60265 DMID-LS-139;
PUBMED-DMID-2/26/2007
Structure-activity relationship studies on anti-HCV activity of
ring-expanded ('fat') nucleobase analogues containing the
imidazo[4,5-e][1,3]diazepine-4,8-dione ring system
Zhang,
P, Zhang, N, Korba, BE, and Hosmane, RS
Bioorg Med Chem Lett 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
12.
60266 DMID-LS-139;
WOS-DMID-2/26/2007
Valopicitabine Dihydrochloride: a Specific Polymerase Inhibitor of
Hepatitis C Virus
Toniutto, P. et al.
Current Opinion in Investigational Drugs 2007. 8(2): 150-158
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243838800007
13.
60267 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
Inhibitors of serine proteases
Lyons, Steve and Perni, Robert B
PATENT: WO
2007016589 ISSUE DATE: 20070208
APPLICATION: 2006 PP:
86pp.
ASSIGNEE: (Vertex
Pharmaceuticals Incorporated, USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
14.
60268 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
Antiviral deoxyribozymes targeting hepatitis C core antigen
RNA
Alfieri, Carolina, Trepanier, Janie, Tanner, Jerome E, and Momparler,
Richard
PATENT: WO
2007014469 ISSUE DATE: 20070208
APPLICATION: 2006 PP:
100pp.
ASSIGNEE: (Chu
Sainte-Justine, Le Centre Hospitalier Universitaire Mere-Enfant
Can.
View Data on the NIAID Therapeutics Website
HYPERLINK:
15.
60269 DMID-LS-139;
PUBMED-DMID-2/26/2007
Protocatechuic aldehyde inhibits hepatitis B virus replication both in
vitro and in vivo
Zhou, Z, Zhang, Y, Ding, XR, Chen, SH, Yang, J, Wang, XJ, Jia, GL, Chen,
HS, Bo, XC, and Wang, SQ
Antiviral Res 2007.
View Data on the NIAID Therapeutics Website
HYPERLINK:
16.
60270 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
Preparation of macrocyclic compounds as HCV NS3 protease
inhibitors
Holloway, MKatharine, Liverton, Nigel J, Ludmerer, Steven W, Mccauley,
John A, Olsen, David B, Rudd, Michael T, Vacca, Joseph P, and Mcintyre, Charles
J
PATENT: US
2007027071 ISSUE DATE: 20070201
APPLICATION: 2006-26173 PP:
142pp.
ASSIGNEE:
(USA)
View Data on the NIAID Therapeutics Website
HYPERLINK:
17.
60271 DMID-LS-139;
PUBMED-DMID-2/26/2007
Efficacy of oseltamivir therapy in ferrets inoculated with different
clades of H5N1 influenza virus
Govorkova, EA, Ilyushina, NA, Boltz, DA, Douglas, A, Yilmaz, N, and
Webster, RG
Antimicrob Agents Chemother 2007.
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HYPERLINK:
18.
60272 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
Preparation of N-(piperazinylcarbonylazolyl)-N'-phenylureas as
anti-cytomegalovirus agents
Zimmermann, Holger, Brueckner, David, Henninger, Kerstin, Hendrix,
Martin, and Radtke, Martin
PATENT: DE
102005033103 ISSUE DATE:
20070125
APPLICATION: 2005 PP:
31pp.
ASSIGNEE: (Bayer Healthcare
AG, Germany
View Data on the NIAID Therapeutics Website
HYPERLINK:
19.
60273 DMID-LS-139;
WOS-DMID-2/26/2007
Natural Products and Chronic Hepatitis C Virus
Azzam, H. et al.
Liver International 2007.
27(1): 17-25
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243534600004
20.
60274 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
Preparation of L-nucleosides as antiviral agents
Yuan, Jiandong, Zhang, Kai, and Ye, Xinjian
PATENT: CN
1891710 ISSUE DATE:
20070110
APPLICATION:
1004 PP:
30pp.
ASSIGNEE: (Brightgene
Bio-Medical (Suzhou) Co., Ltd. Peop. Rep. China
View Data on the NIAID Therapeutics Website
HYPERLINK:
21.
60275 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
The novel C-5 aryl, alkenyl, and alkynyl substituted uracil derivatives
of L-ascorbic acid: Synthesis, cytostatic, and antiviral activity
evaluations
Gazivoda, Tatjana, Raic-Malic, Silvana, Marjanovic, Marko, Kralj,
Marijeta, Pavelic, Kresimir, Balzarini, Jan, De Clercq, Erik, and Mintas,
Mladen
Bioorganic & Medicinal
Chemistry 2007. 15(2):
749-758
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HYPERLINK:
22.
60276 DMID-LS-139;
WOS-DMID-2/26/2007
The Kinetics of Hepatitis C Virus
Herrmann, E. and Zeuzem, S.
European Journal of Gastroenterology & Hepatology 2006 . 18(4): 339-342
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243484200006
23.
60277 DMID-LS-139;
WOS-DMID-2/26/2007
Impact of Human Immune Deficiency Virus Infection on Hepatitis C Virus
Infection and Replication
Parodi, C. et al.
Current Hiv Research 2007.
5(1): 55-67
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243501800005
24.
60278 DMID-LS-139;
PUBMED-DMID-2/26/2007
A dengue Fever viremia model in mice shows reduction in viral replication
and suppression of the inflammatory response after treatment with antiviral
drugs
Schul, W, Liu, W, Xu, HY, Flamand, M, and Vasudevan,
SG
J Infect Dis 2007.
195(5): 665-74
View Data on the NIAID Therapeutics Website
HYPERLINK:
25.
60279 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
Recent patents on treatment of severe acute respiratory syndrome
(SARS)
Zhai, Shumei, Liu, Wei, and Yan, Bing
Recent Patents on Anti-Infective Drug Discovery 2007. 2(1 ): 1-10
View Data on the NIAID Therapeutics Website
HYPERLINK:
26.
60280 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
A mouse-adapted SARS-coronavirus causes disease and mortality in BALB/c
mice
Roberts, Anjeanette, Deming, Damon, Paddock, Christopher D, Cheng, Aaron,
Yount, Boyd, Vogel, Leatrice, Herman, Brian D, Sheahan, Tim, Heise, Mark,
Genrich, Gillian L, Zaki, Sherif R, Baric, Ralph, and Subbarao,
Kanta
PLoS Pathogens
2007. 3(1):
23-37
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HYPERLINK:
27.
60281 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
Preparation of prolyl tripeptides as hepatitis C virus
inhibitors
Hewawasam, Piyasena, Ding, Min, Sun, Li-Qiang, and Scola, Paul
Michael
PATENT: US
2007010455 ISSUE DATE: 20070111
APPLICATION: 2006-22784 PP:
86pp.
ASSIGNEE:
(USA)
View Data on the NIAID Therapeutics Website
HYPERLINK:
28.
60282 DMID-LS-139;
WOS-DMID-2/26/2007
Antiviral Activity of Cyclopropavir and Ether Lipid Esters of Cidofovir
Against Hhv6 and Other Human Herpesviruses
Prichard, M.
Journal of Clinical Virology 2006. 37: S112
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243845000077
29.
60283 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
Antiviral phosphoramidates
Klumpp, Klaus, Martin, Joseph Armstrong, Mcguigan, Christopher, and
Smith, David Bernard
PATENT: WO
2007020193 ISSUE DATE: 20070222
APPLICATION: 2006
ASSIGNEE: (F. Hoffmann-La
Roche A.-G., Switz.
View Data on the NIAID Therapeutics Website
HYPERLINK:
30.
60284 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
Application of multi-substituted acyl thiouracil derivant in preparation
of antiviral drug
Zhou, Pei, Feng, Meiqing, Sun, Chuanwen, Huang, Hai, and Zhou,
Wei
PATENT: CN
1903203 ISSUE DATE:
20070131
APPLICATION: 1002-8153 PP:
11pp.
ASSIGNEE: (Fudan University,
Peop. Rep. China
View Data on the NIAID Therapeutics Website
HYPERLINK:
31.
60285 DMID-LS-139;
SCIFINDER-DMID-2/26/2007
Pyrrolo[2,3-b]pyridine derivatives as protein kinase inhibitors and their
preparation, pharmaceutical compositions and use in the treatment of
diseases
Ibrahim, Prahbha N, Artis, Dean R, Bremer, Ryan, Mamo, Shumeye, Nespi,
Marika, Zhang, Chao, Zhang, Jiazhong, Zhu, Yong-Liang, Tsai, James, Hirth,
Klaus-Peter, Bollag, Gideon, Spevak, Wayne, Cho, Hanna, Gillette, Samuel J, Wu,
Guoxiam, Zhu, Hongyao, and Shi, Shenghua
PATENT: WO
2007002325 ISSUE DATE: 20070104
APPLICATION: 2006 PP: 291
pp.
ASSIGNEE: (Plexxikon, Inc.
USA
View Data on the NIAID Therapeutics Website
HYPERLINK:
32.
60286 DMID-LS-139;
WOS-DMID-2/26/2007
Preventing and Treating Influenza
Baum, S. and Carey, J.
Infections in Medicine 2007.
24(1): 13-+
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243830700006
33.
60287 DMID-LS-139;
WOS-DMID-2/26/2007
Human Rhinovirus 3c Protease as a Potential Target for the Development of
Antiviral Agents
Wang, Q. and Chen, S.
Current Protein & Peptide Science 2007. 8(1): 19-27
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243632700003
34.
60288 DMID-LS-139;
WOS-DMID-2/26/2007
Anti-Enterovirus Activity and Structure-Activity Relationship of a Series
of 2,6-Dihalophenyl-Substituted
1h,3h-Thiazolo[3,4-a]Benzimidazoles
De Palma, A. et al.
Biochemical and Biophysical Research Communications 2007. 353(3): 628-632
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243570000017
35.
60289 DMID-LS-139;
WOS-DMID-2/26/2007
Human Influenza a (H5n1): a Brief Review and Recommendations for
Travelers
Hurtado, T.
Wilderness & Environmental Medicine 2006. 17(4): 276-281
View Data on the NIAID Therapeutics Website
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243309400009
36. 60290
DMID-LS-139;
WOS-DMID-2/26/2007
Long-Term Inhibition of Hepatitis B Virus in Transgenic Mice by
Double-Stranded Adeno-Associated Virus 8-Delivered Short Hairpin
Rna
Chen, C. et al.
Gene Therapy 2007.
14(1): 11-19
HYPERLINK:
http://publishorperish.nih.gov/Gateway.cgi?KeyUT=000243255300002