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Activity Rating AIDS#
A unique identification number assigned to each chemical substance or to each combination of two or more chemical substances that constitutes one record. This number is a 6 digit number which may contain leading zeroes. For example, the AIDS# for AZT is 000001.AUC (Area Under Curve)
Area under the curve results. (A new field, included for future use.)B
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C
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CAS#
A unique identification number assigned by the Chemical Abstracts Service (CAS) to each distinct chemical substance recorded in the CAS Chemical Registry System. This number may contain up to 9 digits. For example the CAS# for Valium is 439-14-5Cell Line (Cytotox or Inhib)
Cell lines are distinct families of cells grown in culture. Cells in the same line are typically clones. Different cell lines have different characteristics. Cell lines are usually associated with cytotoxicity or intracellular test assays.Cell Type
Specific cell types artificially maintained in the laboratory (in-vitro) for scientific purposes. Associated with cytotoxicity or intracellular test assays.Chemical Name
Chemical Name is a systematic name for a chemical compound. This name generally relates information about the identity of a compound in terms of its structure and properties. For example, the Chemical Name for Valium is 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-1-methyl-5-phenyl-DiazepamClass
The general category assigned to a chemical based on toxicity, use, pharmacology, structure, or status in certain chemical lists.Company
Name of company which tested the chemical, markets the drug, or may have a patent on the chemical.Compound Class
The general category assigned to a chemical based on toxicity, use, pharmacology, structure, or status in certain chemical lists.D
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Dose
Compound dose associated with the in vivo test. The dose is a concentration value with units usually given in uM (micromoles/liter) or ug/mL.E
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Enzyme
The enzyme or receptor which is inhibited by a particular compound or drug. For example, the inhibition of reverse transcriptase or cellular DNA polymerases by nucleoside inhibitors. This database contains numerous inhibition values and kinetic parameters for assays involving the inhibition of cellular and viral enzymes.F
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G
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H
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HIV Strain Type
Subgroup of HIV species (also called taxon).I
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Infectious Agent
The agent by which an infection is capable of being transmitted by direct or intimate contact (e.g., sex). These agents include viable microorganisms including bacterium, virus, rickettsia, parasite, fungus, or recombinant, hybrid or mutant that is known or reasonably believed to cause disease in humans or animals.J
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K
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L
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Log Kow or LogP
Log Kow or LogP is the octanol-water partition coefficient for a neutral molecule. The Kow values were calculated by using the EPI (Estimation Programs Interface) Suite developed by the EPA'S Office of Pollution Prevention Toxics and Syracuse Research Corporation (SRC)M
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MOL Formula
Formula that list the kind and number of atoms in a molecule.Molecular Weight
The sum of the atomic weights of all the atoms in a molecule. It is also the weight in atomic mass units of all the atoms in a given formulaMolecular Weight Abbreviations
MOL WGT<= :abbreviation for molecular weight less than or equal to a particular value.
MOL WGT>= :abbreviation for molecular weight greater than or equal to a particular value.
MOL WGT Range :abbreviation for molecular weights within a certain range of values.N
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O
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P
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Q
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R
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Relative Fold Resistance
Can be found using this formula: Relative resistance of a mutant type strain/Relative resistance of a wild type strainS
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Synonym
Common or alternate name.T
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U
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V
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W
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X
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Y
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Z
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